Excited to share our work, now online in Blood Cancer Discovery! We dissected noncoding variants influencing clonal hematopoiesis using MPRA. aacrjournals.org/bloodcancerd... Congrats to Trieu Nguyen, Jessica Jeejan and the team. Thanks to @tewhey.bsky.social and his team for the collaboration!
Germline noncoding risk variants influence clonal hematopoiesis through altered hematopoietic enhancer activity
Abstract. Clonal hematopoiesis of indeterminate potential (CHIP) is a precursor condition characterized by the expansion of mutant hematopoietic stem and progenitor cell (HSPC) clones that increases t...
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