🚨 How do mechanical forces shape a developing organ? Our new #ScienceAdvances @science.org study, led by the amazing @cvagenapantoula.bsky.social, reveals a Piezo1-driven hydraulic mechanism, where mechanical cues control cell volume to guide cardiac formation ❤️🐟 🔗 www.science.org/doi/10.1126/...

Piezo1-mediated mechanohydraulic control of cell volume drives cardiac morphogenesis

Mechanical forces shape the developing heart by controlling cell volume through a Piezo1-driven hydraulic mechanism.

science.org

Check out our latest preprint on the cellular mechanical basis of Voronoi tessellations in epithelia! This biophysics study is inspired by disordered tessellations observed in zebrafish hearts 🤓🐟💙 #SulaimaanLim #ChiuFanLeeLab arxiv.org/html/2512.13...

We're very proud to be releasing the complete male fly CNS connectome! It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators. More soon... www.janelia.org/project-team...

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

janelia.org

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

Out @natcomms.nature.com: our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀 Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!). Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social rdcu.be/eIJm5

The pericardium forms as a distinct structure during heart formation - Nature Communications

The developing heart integrates several progenitor cell types. Here they show that the pericardium enveloping the heart develops among cells that form the mesothelium around inner organs and body cavities, distinct from the classic heart field.

nature.com

Christian Mosimann@chrmosimann.bsky.social · 2y ago

New preprint - unravelling the origins of the mesothelium around the❤️: the pericardium! 🎈 SPIM, scRNA-seq, AFM, #CHD, rats & #zebrafish, all rolled into one. Led by our grad student Hannah Moran, a collab with the Sucharov & Peña labs, CU Anschutz - congrats all! #devbio biorxiv.org/content/10.1...

Back from the London Zebrafish Research Network — a truly inspiring afternoon. Many thanks to @cvagenapantoula.bsky.social, @kkalyviotis.bsky.social and Eleni for putting together such an interactive programme, full of excellent talks - Tim 👏 - and great discussions. Zebbie research at its best!

Want to help prevent aggressive NF1 cancers using cutting-edge models? The GW4 BioMed2 MRC DTP is offering a fully funded 4-year PhD @lsiexeter.bsky.social @exeter.ac.uk to develop a humanised zebrafish model for NF1 resilience. Apply by 20 Oct 2025 www.exeter.ac.uk/study/fundin... #PhD #biomed

PhD:GW4 BioMed2 MRC DTP Studentship | University of Exeter

  The GW4 BioMed2 MRC DTP is offering up to 17 funded studentships across a range of biomedical disciplines, with a start date of October 2026.

exeter.ac.uk

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

New publication | Science Advances www.science.org/doi/10.1126/...

Plasticity of ventricle position after heart looping in heterotaxy with right isomerism

The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.

science.org

🚨Only 4 days to apply!!!🚨Join the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries🔬Connect with top mentors & earn $500 to attend the SDB Annual Meeting 🎉! 👉 www.sdbonline.org/science_comm... #SciComm #DevBio

Very happy to see our preprint on how the mechanosensitive ion channel Piezo1 controls intercellular junction maturation by balancing cortex and membrane tension now published in @jcellsci.bsky.social Congratulations to Ahsan & team! journals.biologists.com/jcs/article/...

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

Mechanochemical coupling of cell shape and organ function optimizes heart size and contractile efficiency in zebrafish

Andrews et al. demonstrate that multiscale feedback between mechanical and chemical cues builds a functional heart to support zebrafish embryonic life. Cell recruitment and organ-scale forces drive tr...

tinyurl.com

Happy to share our work on the role of biomechanical PULSATILITY on lung vessels. Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️‍🩹 www.biorxiv.org/content/10.1...

Pulsatile flow dynamics determine pulmonary arterial architecture

BACKGROUND Single ventricle congenital heart disease (SV-CHD) is a uniformly lethal condition. Survival depends upon the Glenn surgery, which shunts venous blood directly to the pulmonary arteries wit...

biorxiv.org

#Postdocs! Two days left to submit an abstract for the Ethel Browne Harvey Postdoctoral Seminar Series! Deadline: Friday, August 1 bit.ly/3x1ptgb

Society for Developmental Biology@socdevbio.bsky.social · last yr.

#DevBio #Postdocs! Abstracts are being accepted for speakers in the 2025-2026 Ethel Browne Harvey Postdoctoral Seminar Series. SDB postdoctoral members are eligible to apply. Deadline: August 1. #SDBPostdocSeminar bit.ly/3x1ptgb

To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Group Leader - Genome Biology Unit

Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

embl.wd103.myworkdayjobs.com

🚨 NEW REVIEW ALERT! 🔥 Endothelial cells aren’t just lining your vessels — they feel the flow, respond to pressure, and even change their fate. Curious how? 🩸⚙️ Our new review (@Gunawan Lab) breaks down how physical forces shape endothelial plasticity. Check it out 👇 🔗 doi.org/10.1016/j.se...

Can using synthetic approaches to build biology help teach us the design principles of how embryos build themselves? 👷‍♀️🔧 If this is a question that interests you, come and share your thoughts at this Royal Society Workshop on Generative Biology royalsociety.org/science-even...

📣Join us for the DEVELOPMENTAL BIOLOGY COURSE @institutcurie.bsky.social @sorbonne-universite.fr We have fantastic speakers and registration is free! training.institut-curie.org/courses/deve... @karinayaniv.bsky.social @doetschlab.bsky.social @eileen-furlong.bsky.social @jesseveenvliet.bsky.social

Interested in nuclear #mechanobiology? Join us for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC. Find more information and register at: events.faseb.org/event/Mechan... Submit abstracts by August 31, 2025. Please share and see you in October!

Ever wondered how to manipulate mechanical forces in the developing zebrafish heart?🤓 Check out our new protocol by @cvagenapantoula.bsky.social and Hajime, where we describe magnetic bead grafting as an effective approach to study #mechanotransduction!🐟🔬 app.jove.com/t/67604/mani...

See the full list of speakers who will be presenting at our #biologists100 conference. https://100yearsconference.biologists.com/programme/speakers We welcome abstract submissions for both oral and poster presentations by 17 January 2025.

Are you a #DevBio/#StemCell researcher and keen to do more #SciComm? We're looking for new correspondents to work together with the Node team to develop and produce content over the coming year. We're open to any ideas💡 📅Apply by 20 Jan Find out more: thenode.biologists.com/become-a-nod...

Apply for our Pathway to Independence programme, a scheme supporting postdocs going on the job market in 2025 with training, mentorship, profile-raising and networking opportunities. Apply by 31 Jan 2025: https://buff.ly/3VJGgDC

"Biophysics of Motile Cilia" Heraeus workshop: program online! Application deadline: 12.01.25. Topics: #axoneme #synchronization #navigation #ciliopathies ... Bad Honnef, Germany, 30.03.-02.04.2025 www.we-heraeus-stiftung.de/veranstaltungen/the-biophysics-of-motile-cilia-from-structure-to-function

📢#ECRs - join us at the Biologists @ 100 conference ECR event, focusing on career opportunities inside and outside of academia. We hope this event will allow you to network with fellow ECRs ahead of the main conference. #biologists100 📅Early-bird & abstract deadline: 17 Jan buff.ly/3Zd27UE

✨Happy Holidays from the Vermot lab!🎄🎅❄️☃️

Yes! We are hiring! Looking for highly motivated people to make good use of our #ERC_SyG money 💶! The project is super cool, and the people are the best!! There are plenty of opportunities for international collaborations, too! Please help us spread the word!

Yaara Tevet@yaaratevet.bsky.social · 2y ago

Karina Yaniv Lab at the Weizmann Institute is seeking PhD students and postdoctoral researchers. Come work with us!

Check out our latest review on the mechanics of cardiac morphogenesis!🤓💙 #mechanobiology #devbio www.sciencedirect.com/science/arti...

Rhythmic forces shaping the zebrafish cardiac system

The structural development of the heart depends heavily on mechanical forces, and rhythmic contractions generate essential physical stimuli during mor…

sciencedirect.com

The birth of fruit fly's central nervous system imaged with multicolor #adaptive #lightsheet microscopy. The microscope self-aligns to a signal that appears during imaging. www.nature.com/articles/nbt...

Only a few days left to submit your abstracts for our amazing spring meeting in collaboration with @biologists.bsky.social and BSCB! Submit before the 13th of December 100yearsconference.biologists.com Don't forget to apply for your conference grants by the 10th of January bsdb.org/membership/#...