Did you ever wonder how good any disease predictor based only on genetic data could be? Answer: it is a function of the heritability of the markers used, and might not be very high, without ~all~ the genetic variants identified. Figure 5. www.pivotscipub.com/hpgg/4/3/000...
The Quantitative Genetics of Human Disease: 2 Polygenic Risk Scores
The Quantitative Genetics of Human Disease: 2 Polygenic Risk Scores
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