New study from the Lab! Jinyang Liang assesses the possibility of inferring ancestral alleles (aka allele polarization) without outgroup sequence, using the ancestral recombination graph (ARG) alone. Here are some of our findings. (1/5)
Polarizing SNPs without outgroup https://www.biorxiv.org/content/10.1101/2025.01.31.635919v1