An utterly bleak picture of the future of academic science in America

Joshua Weitz@joshuasweitz.bsky.social · 7mo ago

The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.

Incubated craving of cocaine or sucrose in 🐀 depends on NMDAR and calcium/calmodulin-dependent protein kinase II signaling in the prelimbic cortex, with cocaine craving specifically associated with increased kinase activity

Inactivation of NMDAR and CaMKII signaling within the prelimbic cortex blocks incubated cocaine- and sucrose-craving

Neuropsychopharmacology - Inactivation of NMDAR and CaMKII signaling within the prelimbic cortex blocks incubated cocaine- and sucrose-craving

nature.com

My friends often joke about how complex my neuroimaging research sounds—and let's be honest, we scientists do have a habit of making things complicated! But recently, I had the opportunity to contribute to a study that is refreshingly straightforward.

How are advanced PET imaging biomarkers 🔬 enhancing our ability to study neuroimmune dynamics 🧠🛡️ in psychiatric illness 😔 to refine diagnostics 🩺 and discover new therapies ✨? Find out here 👇

Imaging Neuroimmune Dysfunction: From TSPO to Emerging PET Targets

Dysregulation of the neuroimmune system is increasingly recognized as a key contributor to psychiatric illness, yet its complexity and the limitations of current methodologies have hindered a clear…

biologicalpsychiatryjournal.com

1) Neurobiology of Substance Use Disorders using PET neuroimaging. 2) Developing and translating a novel radioligand for the NMDA GluN2B receptor 3) Thoroughly enjoyed “It’s What’s Inside” on Netflix

josh hardman@josh-hardman.bsky.social · 2y ago

Bluesky Psychedelics People: Let's (re-)intro ourselves to one another! Quote this post and tell us: 1) What you do in the field 2) A project you're currently working on 3) A show/film/book you're enjoying