Dynamic42

@dynamic42.bsky.social

Recreating human physiology in vitro for better therapies and disease research without animal experiments. Posting about news and insights from the organ-on-chip world. Learn more about us here --> https://dynamic42.com/

Part 6 of Minds Behind Organ-on-Chip season 2 features Hristina Koceva, who shares insights into her work on establishing a human iPSC-based alveolus-on-chip model to study immunometabolic modulation during Influenza A infection. Watch here: zurl.co/iJIZ4

Minds Behind Organ-on-Chip – Hristina Koceva (Mosig Lab, University Hospital Jena, Germany)

We had the opportunity to speak to Hristina, PhD at the Mosig Lab at University Hospital Jena in Germany. She is working on establishing a human iPSC-based a...

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Summer heat? High. Starter Kit price? Low. ❄️ Get started with DynamicOrgan® Starter Kits for under €500 and receive free 2-month Online Academy access. Valid until 31 Aug 2026. Terms & Conditions apply Learn more here: zurl.co/hcuZ1

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Part 5 of Minds Behind Organ-on-Chip season 2 features Christian Maass, lead of MPSlabs at ESQlabs. Chris shares insights into our joint project on predicting drug safety during pregnancy by combining MPS in vitro data with digital twinning. Watch here: zurl.co/w6fat

Minds Behind Organ-on-Chip - Christian Maass (MPSlabs, BU of ESQlabs GmbH, Germany)

We had the opportunity to speak to Christian Maass, Lead of MPSlabs, a business unit of ESQlabs GmbH in Germany. Chris talks about our joint project on predi...

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Part 4 of Minds Behind Organ-on-Chip season 2 features Dr. Nanci dos Santos Ferreira from KU Leuven in Belgium, who shares insights into Hepatitis E Virus (HEV) replication and dissemination in a human enteroid-derived gut-on-chip model. Watch here: zurl.co/laM1I

Minds Behind Organ-on-Chip - Dr. Nanci dos Santos Ferreira (Porto Lab, KU Leuven, Belgium)

We had the opportunity to speak to Nanci, PostDoc at the Porto Lab at KU Leuven in Belgium. She is working on the development of an human intestinal enteroi...

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No need to let organ-on-chip adoption make you sweat. ☀️ Our DynamicOrgan® Starter Kits are available for under €500 this summer, including free 2-month Online Academy access. Terms & Conditions apply Learn more here: zurl.co/UsxRX

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Part 3 of Minds Behind Organ-on-Chip season 2 features Markus Gresnikt, who shares insights into host pathogen interactions during the infection with the yeast Candida albicans in gut- and vaginal mucosa-on-chip models. Watch here: zurl.co/OQ5D0

Minds Behind Organ-on-Chip - Dr. Mark Gresnigt (Hans Knöll Institute (Leibniz-HKI), Germany)

We had the opportunity to speak to Mark the Junior Research Group Leader of the Adaptive Pathogenicity Strategies group at the Leibniz Institute for Natural ...

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Choosing the right biochip format is an important step when building an organ model. Different research questions require different microenvironments from compartmentalized co-cultures & 3D spheroid models to integrated sensor readouts for barrier integrity or oxygen monitoring.

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Minds Behind Organ-on-Chip is back for season 2! In part 1, Maria Warschinke shares her work on an immunocompetent intestine-on-chip model for Clostridioides difficile infection in a hypoxic microenvironment. Watch here: zurl.co/2sli0

Minds Behind Organ-on-Chip - Maria Warschinke (University Hospital Jena, Germany)

We had the opportunity to speak to Maria a PhD student in the research group, AG Inspire at the University Hospital Jena in Germany. She is working on an imm...

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We’re excited to welcome Darlin Lantigua as Dynamic42’s new Field Application Specialist in the United States. We’re strengthening local support for researchers implementing advanced organ-on-chip applications with our DynamicOrgan® platform. More here: zurl.co/p5UHu

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It’s hot outside — but your lab budget doesn’t have to sweat. ☀️ DynamicOrgan® Starter Kits are available this summer for under €500, including free 2-month Online Academy access. Terms & Conditions apply Learn more here: zurl.co/j3v0G

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Last call - tomorrow 4 PM CET! Don’t miss “Advanced BBB on Chip Models for Brain Cancer Research” - June 18, 2026 (4 PM CET). Talks + panel on tumor–BBB interactions and drug transport & efficacy testing. Register: zurl.co/FkL3f

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Some researchers hesitate because they think #OrganOnChip is too complicated. However, as with any new technology, with a step-by-step approach and well-thought-out experimental design, this can soon become a staple method in your lab. Or as Joanna says : "You will be just fine"!

1 week left! June 18, 4 PM CET: Advanced BBB on Chip Models for Brain Cancer Research. 🎯 Highlights: • BBB on Chip model setup & optimization • Tumor–BBB interactions (glioma & beyond) • Drug transport & efficacy testing across the BBB Register: zurl.co/cQKad

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Based in Berlin or nearby? Join us at the Networking Event on Human 3D Organ Models organized by Charité 3R and Einstein Center 3R. Discover our organ-on-chip platform and meet Marty to discuss applications for human-relevant research and 3R-aligned innovation.

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How do we achieve reproducible TEER measurements? 1️⃣ fixed, planar electrodes for consistent positioning 2️⃣ measurements inside the incubator to minimize temperature variations

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Oxygen inside chips used to be a black box. Now, integrated optical sensors allow continuous, non-invasive O₂ monitoring under flow. This reveals real time metabolism, drug effects & true physiological conditions. A core biological parameter for in vitro models.

How much oxygen are cells exposed to inside organ-on-chip models?  Together with PyroScience, we developed the first integrated organ-on-chip platform with non-invasive real-time O₂ sensing. See it live at #MPS2026 📍 Booth 515/517 ☕ Demo schedule: zurl.co/ojj6T

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We’ve arrived in Washington, DC and can’t wait to see you at #MPS2026! Today: #TEER & #oxygen measurement live with Tom & Amélie Tomorrow: Posters on integrated TEER + PDAC-on-chip Daily: Live oxygen sensor demos at Booth 515/517 with PyroScience Excited to exchange ideas!

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Beyond endpoint assays: how do you track real tissue dynamics in organ-on-chip systems? Join our educational workshop at #MPS2026 to explore real-time TEER and O₂ monitoring — with hands-on training in biochip handling, seeding, perfusion setup, and live readouts. #TEER #Oxygen

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In IBD, loss of butyrate during dysbiosis may weaken mucosal defense against C. albicans. With a Colitis-on-Chip the authors showed butyrate strengthens barrier integrity & boosts macrophage antifungal defense while limiting inflammatory damage. Summary: zurl.co/5F0IS

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Two weeks until #MPS2026. What you shouldn’t miss: 1️⃣ Educational Workshop: Perform TEER/O₂ live readouts in Dynamic42 biochips 2️⃣ Live demo with PyroScience: Come to booth #515 to see our O₂ sensor system in action. 3️⃣ Posters: TEER for gut-on-chip + PDAC-on-chip

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[New Paper] A microbiota-derived metabolite, a human colitis-on-chip, and a new angle on IBD barrier repair. Congratulations to Tim Kaden et al. on this recent publication in Frontiers in Immunology. Read the article here: zurl.co/zSo6m

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