Chemistry World

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Chemistry: Covered. The latest news, research, features and opinion from across the chemical sciences. Published by the Royal Society of Chemistry. https://www.chemistryworld.com/

Lots of thesis writing guides don’t mention acknowledgements or gloss over them as simply thanking a list of people and organisations. Ada McVean digs deeper and shares her tips for writing your thesis acknowledgments. Read 👇 @rsc.org @adamcvean.bsky.social www.chemistryworld.com/careers/how-...

How to write thesis acknowledgements

Tips for deciding who and how to thank those who have supported you through your PhD or dissertation

chemistryworld.com

‘It is mere rubbish thinking, at present, of the origin of life,’ Charles Darwin wrote to his friend Joseph Hooker in 1863. Phil Ball unpacks some of these theories and looks into the research around the key ‘ingredients of life’. @philipcball.bsky.social www.chemistryworld.com/opinion/our-...

Our cosmic origins remain plausible, not proven

The evidence is there that the molecular ingredients for life can form in space, but that doesn't mean that they did

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‘Excellent enzyme discovery, excellent pathway engineering, and a genuinely clever decision about where the hard chemistry ought to be done,’ comments Jay Keasling, a bioengineer at the University of California who was not involved in this study. #ChemSky www.chemistryworld.com/news/bakers-...

Baker’s yeast engineered to produce precursor for essential cancer drugs

Biosynthesis potentially offers a more efficient way to produce etoposide and teniposide than current synthetic pathways

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There’s going to be a day that we can’t use dichloromethane & it’s coming soon – it’s better to stop it now & work around it,’ says Paul Richardson who leads analytical and synthesis technologies at Pfizer’s San Diego site. Read on: @rebeccatrager.bsky.social www.chemistryworld.com/industry/pfi...

Pfizer’s green chemistry team turns 25

What began as a grassroots initiative has become embedded across Pfizer's research and manufacturing operations, helping reshape processes from Viagra to Paxlovid

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Natural product chemist Sarah O’Connor was drawn to the University of Chicago since it was in a big city & for its ‘common core’ curriculum which saw all students take courses in literature & history regardless of major. Read our latest In Situ 👇 #ChemSky www.chemistryworld.com/opinion/sara...

Sarah O’Connor: ‘There’s nothing that matches that thrill of discovery’

The natural product chemist talks growing up in New York, her dad's late pursuit of a PhD, and her journey to plant chemistry and to Germany

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Accelerated approval has been granted to molecular glue protein degrader drug, iberdomide which targets the cereblon protein, for use in a combination therapy to treat multiple myeloma patients whose cancer no longer responds to standard treatments. Read 👇 www.chemistryworld.com/news/protein...

Protein degrader approval offers hope to relapsed multiple myeloma patients

Highly potent molecular glue drug iberdomide doubles the number of patients reaching fewer than one myeloma cell per 100,000 in bone marrow

chemistryworld.com

The ubiquitin code is complex. Polyubiquitin chains come in linear & branched forms, and research teams are only just getting to grips with matching the huge variety found in cells to their specific function. Rachel Brazil explores in our her feature: @rsc.org www.chemistryworld.com/features/cra...

Cracking the ubiquitin code to unlock new drug targets

The approval of the first Protac cancer drug marks a turning point in medicine - but scientists are only beginning to decode the complex molecular language that makes it possible

chemistryworld.com

Benchmark performance often determines where drug-discovery models rank on leaderboards & which are considered state of the art. Now, researchers have found data issues across many of the most widely used benchmarks for AI-driven drug discovery. Read 👇 www.chemistryworld.com/news/benchma...

Benchmark flaws may be distorting AI drug-discovery leaderboards

Audit identifies subtle but consequential issues, such as conflicting labels and train-test leakage, in numerous benchmark datasets

chemistryworld.com

‘Transparent & secure international collaborations create perspectives that deepen our understanding of global challenges, promote scientific discovery and strengthen US innovations,’ says University of Illinois Urbana-Champaign spokesperson Patrick Wade. www.chemistryworld.com/news/30-us-u...

30 US universities ordered to audit foreign research partnerships

Pentagon says review must be finished by the end of August to maintain federal funding

chemistryworld.com

US researchers have developed a versatile computational system called Goose, which rapidly generates thousands of new disordered protein regions per minute that can be tested in cells to reveal distinct sequence-to-function relationships. Read: #ChemSky www.chemistryworld.com/news/tool-fo...

Tool for designer disordered proteins unentangles their function

Mysterious structure-function relationship of intrinsically disordered proteins probed by machine-learning platform

chemistryworld.com

By reconstructing a complex 45-enzyme biosynthetic pathway inside yeast, researchers have unlocked the direct microbial synthesis of key precursors that could offer a more efficient way to make the drugs than the current synthetic routes. Read: #ChemSky www.chemistryworld.com/news/bakers-...

Baker’s yeast engineered to produce precursor for essential cancer drugs

Biosynthesis potentially offers a more efficient way to produce etoposide and teniposide than current synthetic pathways

chemistryworld.com

The US Department of War has ordered major universities including Harvard and MIT to audit and report on their international research collaborations by the end of the month or they risk losing federal funding. Rebecca Trager reports: @rebeccatrager.bsky.social www.chemistryworld.com/news/30-us-u...

30 US universities ordered to audit foreign research partnerships

Pentagon says review must be finished by the end of August to maintain federal funding

chemistryworld.com