Last week, #FlatironCCN hosted a Junior Theoretical Neuroscientists Workshop to connect talented young theorists studying different topics with each other and the Flatiron Institute's theoretical #neuroscience community. Credit: Emily Tan/Simons Foundation

Happy #NationalInternDay! This summer, we're hosting over 60 interns to work on projects across computational science and scientific outreach. Read more about our Summer at Simons program: https://bit.ly/4w2r8Aq #math #science

From John Michell's 1783 calculations and Karl Schwarzschild and Albert Einstein's 1916 theories to the work of astrophysicists today, black holes remain a mysterious and fascinating. At the @flatironinstitute.org, scientists are advancing the frontiers of black hole research: https://bit.ly/4f9DgZW

Delving Into the Mathematical Absurdities of Black Holes

Delving Into the Mathematical Absurdities of Black Holes on Simons Foundation

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When researchers reported they used a quantum computer to complete a task that would take a classical computer tens of thousands of years to solve, physicists at the @flatironinstitute.org were skeptical. So, they set out to prove the claim wrong: https://bit.ly/4f2FCtB #science #physics #math

The Mathematical Tools Trailblazing the Quantum Future

The Mathematical Tools Trailblazing the Quantum Future on Simons Foundation

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This week, #FlatironCCA is hosting 2026 CMB Summer School where participants are learning core concepts and practical tools for CMB data analysis and simulations. #science #astrophysics

I'm giving a poster on MIMIC at #ISMB2026 today (C-211)! Drop by and chat with me about multimodal modeling for DNA, RNA, and protein biology. Inference code + checkpoints + sample data are all now available on GitHub/HuggingFace. github.com/PolymathicAI...

Samuel Sledzieski@samsl.io · 3mo ago

Introducing MIMIC: a new foundation model trained natively across DNA, RNA and proteins. MIMIC is multimodal and generative: it can use structure, regulation, evolution, and experimental context to infer missing biology or design new sequences. 🧵⬇️

Simons Foundation president David Spergel recently joined the New York Academy of Sciences podcast Shaping Science with Nick Dirks to discuss the unique role philanthropy can play in advancing bold scientific research. Watch the full interview: https://bit.ly/4vRBG62 #science #math #philanthropy

Biologists at the @flatironinstitute.org are working to gain deeper and more mechanistic understandings of living systems by utilizing mathematical models. Most recently, researchers used this strategy to solve a mystery surrounding fruit fly sperm: https://bit.ly/4oKB2Vx #science #biology #math

By leveraging a classical mathematical function, #FlatironCCM researchers created a new method that enables molecular dynamics simulations to run 2.5 to seven times as fast — all without sacrificing accuracy. Read more: https://bit.ly/4oLYtgR #math #science

By studying the movements of individual fruit fly sperm, experimental and theoretical researchers at the @flatironinstitute.org were able to work together to understand the sperm's collective behavior: https://bit.ly/4oKB2Vx #science #biology #math

Fruit fly sperm are some of the longest in the animal kingdom — but how do they avoid getting tangled? New research from #FlatironCCB has the answer: https://bit.ly/4oKB2Vx #biology #science

ICYMI: By adapting a 1980s algorithm to modern tensor networks, researchers at the @flatironinstitute.org used classical computers to solve problems previously claimed to be solvable only by quantum computers. Read more: https://bit.ly/42QeMiK #physics #science #math #FlatironCCQ

Quantum Dynamics Breakthrough Overturns Claim of ‘Quantum Supremacy’

Flatiron Institute research shows that classical computers can tackle a class of problems previously claimed to be solvable only by quantum computers.

simonsfoundation.org

Open-source proof assistant Lean is transforming how #math gets done: https://bit.ly/3QJUjJR

From Trust to Verification: Lean’s Impact on Mathematics

From Trust to Verification: Lean’s Impact on Mathematics on Simons Foundation

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New @flatironinstitute.org research on fruit fly sperm helps explain their surprisingly organized behavior: https://bit.ly/4oKB2Vx #science #math #biology

Researchers at our @flatironinstitute.org were able to speed up molecular dynamics simulations — like this one — by applying a classical mathematical function: https://bit.ly/4oLYtgR #science #math

ICYMI: #FlatironCCA astrophysicist Maximiliano Isi and colleagues nearly doubled the number of black hole collisions ever identified. Read more about the new observations from the LIGO-Virgo-KAGRA collaboration: https://bit.ly/42XYmF1 #science #astronomy

Black Hole Discoveries Abound in Newly Released LIGO-Virgo Catalog

Black Hole Discoveries Abound in Newly Released LIGO-Virgo Catalog on Simons Foundation

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Over 20% of the workload on the world's 500 fastest supercomputers is spent simulating how atoms and molecules move, but a new mathematical method from the @flatironinstitute is enabling these simulations to run 2.5 to seven times as fast: https://bit.ly/4oLYtgR #science #math #biology

#FlatironCCM researchers leveraged a classical mathematical function to speed up simulations of molecular behavior, which could meaningfully accelerate molecular dynamics workloads across science. Read more: bit.ly/4oLYtgR #math #science

Mathematicians Unleash Multifold Speed Boost for Supercomputer Simulations of Molecules

Mathematicians Unleash Multifold Speed Boost for Supercomputer Simulations of Molecules on Simons Foundation

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A new mathematical model from @flatironinstitute.org biologists explains how fruit fly sperm avoid getting tangled up: https://bit.ly/4oKB2Vx #science #biology #FlatironCCB

Researchers at the @flatironinstitute.org developed a new method to run molecular dynamics simulations up to 7x faster — without sacrificing accuracy: https://bit.ly/4oLYtgR #science #math

Mathematicians Unleash Multifold Speed Boost for Supercomputer Simulations of Molecules

Mathematicians Unleash Multifold Speed Boost for Supercomputer Simulations of Molecules on Simons Foundation

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Our 2025 annual report is here! This report celebrates math's central role in supporting #science and shaping our understanding of everything from string theory and black holes to ocean microbes and autism: https://bit.ly/4vrumhh #math #philanthropy

2025 Annual Report

2025 Annual Report on Simons Foundation

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Researchers at #FlatironCCB are investigating how the collective movement of giant sperm in fruit flies gives rise to folded layers of motion. Read more about their new hypothesis: https://bit.ly/4oKB2Vx #science #biology

Mysteries of Fruit Fly Sperm Untangled by Mathematical Models

Biologists at the Flatiron Institute’s Center for Computational Biology used mathematical models to improve our understanding of sperm structure and function.

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New in @nature.com Physics: @flatironinstitute.org researchers combined experiments and theoretical models to untangle a mystery surrounding fruit fly sperm: https://bit.ly/3QD0Nua #science #biology #FlatironCCB

Mysteries of Fruit Fly Sperm Untangled by Mathematical Models

Biologists at the Flatiron Institute’s Center for Computational Biology used mathematical models to improve our understanding of sperm structure and function.

simonsfoundation.org

*Preprint Alert*: How do we measure resolution when biomolecules won't sit still? 🔬 Estimating it for a static cryo-EM reconstruction is standard. But what about a conformational ensemble? arxiv.org/abs/2606.14449 with the amazing henryhmattingly.bsky.social and @lukeevanshandle.bsky.social #cryoEM

We're hosting over 60 summer interns across the foundation and at the @flatironinstitute.org. Here's to a fun and engaging summer! #science #math

@flatironinstitute.org physicist Marc Ritter and filmmaker Elsa Wong teamed up to create MOSS, a short film that explores feedback loops between our ideas and the natural world. Stream full film: https://bit.ly/4fxUsue #science #math #InfiniteSums #Symbiosis

In his book, "The Proof in the Code: How a Truth Machine Is Transforming Math and AI," @kevinhartnett.bsky.social tells the story of computer program Lean in an effort to answer a longstanding question: Can computers reveal universal truths? Out today from @quantabooks.org: https://bit.ly/43X5To1

New data from the LIGO-Virgo-KAGRA collaboration revealed two distinct types of black holes: small and slowly spinning ones vs. heavier ones that spin much faster: https://bit.ly/42XYmF1 #science #astrophysics

#FlatironCCN researcher SueYeon Chung has been selected as a 2026 McKnight Scholar for her work on neural population geometry. Congratulations, SueYeon! https://bit.ly/4g52eM7 #science #neuroscience #math

CCN Researcher SueYeon Chung Named McKnight Scholar

CCN Researcher SueYeon Chung Named McKnight Scholar on Simons Foundation

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Concrete Cosmos, a Symbiosis short film created by @flatironinstitute.org researcher Adrian Bayer and filmmaker Adonis Williams, reveals surprising parallels between the structure of the deep universe and daily life on Earth. Watch full film: https://bit.ly/4fcdI08 #InfiniteSums #math #astrophysics