Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com www.jobs.ac.uk/job/DQY475/r...

Research Fellow (Postdoctoral) at University of Birmingham

Explore an exciting academic career as a Research Fellow (Postdoctoral). Don't miss out on other academic jobs. Click to apply and explore more opportunities.

jobs.ac.uk

In our most recent work David Forrest has discovered a widespread mechanisms linking transcription initiation to DNA supercoiling... www.nature.com/articles/s41...

@ewarman.bsky.social has followed up on her discovery of bidirectional promoters in bacteria by defining their basic rules for regulation and links to gene expression noise... academic.oup.com/nar/article/...

Bidirectional promoters in Escherichia coli: regulatory rules and implications for gene expression noise

Abstract. In prokaryotes, bidirectional promoters are pseudo-symmetrical DNA sequences that stimulate divergent transcription. Ubiquitous, and far more lik

academic.oup.com

A busy few weeks for the lab 🥵... three new stories published. The first describes activation of transcription by DNA distortion academic.oup.com/nar/article/...

Activation of bacterial transcription by distortion of promoter base pairing

Abstract. Bacterial RNA polymerase binds and unwinds promoter DNA to initiate transcription. The process is often inefficient and can be stimulated by acti

academic.oup.com

Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation. www.findaphd.com/phds/?Keywor...

grainger birmingham PhD Projects, Programmes & Scholarships - 3 PhDs Listed

FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.

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@danielabarilla.bsky.social kicking off #BioPhyChrom2025 - a fantastic turn out too...

'We show that the VqmAj homologs can indeed detect (host autoinducer) DPO and, in response, activate the lytic pathway. Our observation indicates that jVP882 is a member of a large family of globally-dispersed quorum-sensing-responsive temperate phages.' www.biorxiv.org/content/10.1...

A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species

Temperate phages oscillate between lysogeny, a genomic maintenance state within a bacterial host, and lytic replication, in which the host is killed, and newly made phage particles are released. Succe...

biorxiv.org

📢 Dear lovers of prokaryotic chromosomes: Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August ⏳. Join us! @biophychrom.bsky.social @danielabarilla.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social #microsky

Talk slots full but we can take late breaking poster abstracts until August 7th. Hope to see you in York to hear about your chromosome story 🧬🦠🧫 www.eventsforce.net/biochemsoc/f... @vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social

How are bacterial transport machineries regulated by external cues? @brochadolab.bsky.social &co identify environmental chemicals that regulate #transporter transcription, identifying the TF Rob as a key modulator of #EffluxPump expression in #Ecoli #AMR @plosbiology.org 🧪 plos.io/46pUM9Q

Just few days left to register for this chromosome biology fête! 🧬🧬🧬 ⏳📆 16 July www.eventsforce.net/biochemsoc/f... @vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social

Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes 🧬! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon. @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biophychrom.bsky.social

🚨 Out now! West African South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems #MicroSky 🦠 #Phage @mblokesch.bsky.social www.nature.com/articles/s41...

West African–South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems - Nature Microbiology

The West African–South American lineage of Vibrio cholerae contains multiple distinct anti-phage defence systems that provide resistance to various phage families, including vibriophage ICP1, a key pr...

nature.com

Join us in York for the Biology & Physics of Prokaryotic Chromosomes! 🧬 #Microsky #Archaeasky www.biochemistry.org/events-and-t... @biochemsoc.bsky.social @damelab.bsky.social @graingerlab.bsky.social @vslioy.bsky.social

Daniela Barillà@danielabarilla.bsky.social · last yr.

Fancy a journey back in time to Roman Eboracum by walking on the city walls?And a visit to the Norman Clifford Tower? A stroll down the Middle Age Shambles? All this whilst enjoying a full immersion into chromosome biology? 🧬 Join us at The Biology & Physics of Prokaryotic Chromosomes! 🦠🧪🧬

Fascinating new PLoS Biology paper from George Schaible et al in the Hatzenpichler Lab at Montana State “𝘈𝘴 𝘵𝘩𝘦 𝘰𝘯𝘭𝘺 𝘦𝘹𝘢𝘮𝘱𝘭𝘦 𝘰𝘧 𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘢 𝘵𝘩𝘢𝘵 𝘦𝘹𝘩𝘪𝘣𝘪𝘵 𝘰𝘣𝘭𝘪𝘨𝘢𝘵𝘦 𝘮𝘶𝘭𝘵𝘪𝘤𝘦𝘭𝘭𝘶𝘭𝘢𝘳𝘪𝘵𝘺, 𝘔𝘔𝘉 𝘱𝘳𝘰𝘷𝘪𝘥𝘦 𝘢𝘯 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘦𝘹𝘢𝘮𝘱𝘭𝘦 𝘰𝘧 𝘱𝘰𝘴𝘴𝘪𝘣𝘭𝘦 𝘮𝘦𝘤𝘩𝘢𝘯𝘪𝘴𝘮𝘴 𝘣𝘦𝘩𝘪𝘯𝘥 𝘵𝘩𝘪𝘴 𝘱𝘳𝘰𝘧𝘰𝘶𝘯𝘥 𝘴𝘵𝘦𝘱 𝘪𝘯 𝘭𝘪𝘧𝘦’𝘴 𝘦𝘷𝘰𝘭𝘶𝘵𝘪𝘰𝘯𝘢𝘳𝘺 𝘩𝘪𝘴𝘵𝘰𝘳𝘺 𝘰𝘯 𝘌𝘢𝘳𝘵𝘩”

These Tiny Magnetic Bacteria Act Like a Single Body – And Could Explain the Origins of Complex Life

Tiny magnetic bacteria that live in tightly bound groups are showing scientists how life might have evolved complex, multicellular forms. These rare bacteria can’t survive alone – they depend on one a...

scitechdaily.com

We loved being back on campus for Master's hour on team working! @unibirmingham.bsky.social The students created content to highlight the excellent research from one of our customers! It's all about the Long Reads 👀 @graingerlab.bsky.social @fozzz21.bsky.social @imibirmingham.bsky.social #MicroSky

Super excited to share the peer-reviewed version of the KorAB paper. Amazing to work such talented collaborators and thanks to the reviewers for making the work even better! www.nature.com/articles/s41...

KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid - Nature Microbiology

Structural and single-molecule analyses show the CTPase, KorB, is a sliding DNA clamp that interacts with a clamp-locking protein KorA to inhibit gene expression over distances of more than 1 kb in th...

nature.com

If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)

2x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) — join us! www.jobs.manchester.ac.uk/Job/JobDetai...

Chair Appointments within Manchester Institute of Biotechnology:Manchester Institute of Biotechnology

jobs.manchester.ac.uk

PhD projects available in our lab all listed in the below link. All focus on bacterial gene regulation, in the context of basic understanding, disease, or antibiotic resistance. Deadlines in January... www.findaphd.com/phds/?Keywor...

grainger birmingham PhD Projects, Programmes & Scholarships

FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.

findaphd.com