From mobile DNA to medicine: Fusion Conference highlights the therapeutic potential of endogenous retroelements in human disease: Trends in Genetics www.cell.com/trends/genet...

From mobile DNA to medicine: Fusion Conference highlights the therapeutic potential of endogenous retroelements in human disease

Endogenous retroelements (EREs) are a subset of transposable elements (TEs) that mobilize via an RNA intermediate. They include retrotransposable elements such as long interspersed nuclear elements (L...

cell.com

👏Thanks to @preprintclub.bsky.social on this #dayofimmunology #worldimmunologyday for their valued contributions to our Preprint Watch Journal Clubs

Preprint Club - Immunology@preprintclub.bsky.social · 3mo ago

Happy International Day of Immunology! We are happy to contribute to the review of the latest preprints across diverse immunology fields. Read our preprint reviews here: www.preprintclub.com/preprint-rev... and join the initiative! 🦠🤓📗

Interested in viral mimicry in cancer? Stop by our exciting Educational Session #AACR2026 this Friday to learn how tumors can behave like virus - and what that means for therapy @chiappinellilab.bsky.social @neoviral.bsky.social @theaacr.bsky.social @foxchasecancer.bsky.social

Last chance to SIGN UP FOR FREE and hear the latest on immune aging and immunotherapy to extend healthspan from the following founders in the field, online, all welcome, Mar 23 - 25: www.eventbrite.com/e/internatio...

International Course of Immunotherapy March 23-25, 2026

11th Edition Theme: Targeting Immune Aging | Time: 9:00am-1.15pm NYC; 14:00-18.15h Paris; 10:00am-2.15pm Sao Paulo

eventbrite.com

🚨 Last days to register to next week #Immunoschool! This year’s theme: "Targeting Immune Aging " Free registration @ www.eventbrite.com/e/internatio... #ImmunoSchool #Immunotherapy #AgingResearch

International Course of Immunotherapy March 23-25, 2026

11th Edition Theme: Targeting Immune Aging | Time: 9:00am-1.15pm NYC; 14:00-18.15h Paris; 10:00am-2.15pm Sao Paulo

eventbrite.com

🚨 Last days to register to next week #Immunoschool! This year’s theme: "Targeting Immune Aging " Free registration @ www.eventbrite.com/e/internatio... #ImmunoSchool #Immunotherapy #AgingResearch

International Course of Immunotherapy March 23-25, 2026

11th Edition Theme: Targeting Immune Aging | Time: 9:00am-1.15pm NYC; 14:00-18.15h Paris; 10:00am-2.15pm Sao Paulo

eventbrite.com

The Trump Administration is waging war on universities by suspending their funds. N.I.H. grants to universities are down by more than 90 per cent in the current fiscal year; so far in 2026, the National Cancer Institute hasn’t made a single grant. newyorkermag.visitlink.me/oxA7Ey

The Unmaking of the American University

For decades, research universities have relied on federal funding, with no guarantee that it will last. Now their survival may depend on compliance with the government.

newyorkermag.visitlink.me

At Immunoschool, Eicke Latz will discuss targeting inflammasomes, the innate immune sensors linking lifestyle exposures - from Western diet to metabolic stress - to the chronic inflammation that impacts healthspan. Hear more at the online Immunoschool Mar 23 - 25: www.eventbrite.com/e/internatio...

3 days. Global faculty and learners of all career stages. Aging, immunity and translation at the cutting edge. Save your spot: www.eventbrite.com/e/internatio... Explore the program: immunoschool.org The second speaker will be Vishwa Deep Dixit of the Yale Univertsity Center for Research on Aging

FREE registration is now open for this year’s International Immunoschool on IMMUNE AGING: ✍️ www.eventbrite.com/e/internatio... From mechanism to translation, there’s something for every career stage. Explore the program here: 🧐 immunoschool.org First speaker is @miriammerad.bsky.social...

📢 SIGN & SHARE THE PETITION! 📢 New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW

Sign the Petition

Support a New York State Biomedical Institute for a Healthier, More Affordable Future

c.org

Check out our highlight of an exciting new preprint by Dr. Claudia Rivera from Dr. Yasmine Belkaid's group 👇

Nicolas Vabret@neoviral.bsky.social · 9mo ago

www.nature.com/articles/s41...

www.nature.com/articles/s41...

Interesting study from the ppl @solvingforsci.bsky.social. Very much in line with our earlier findings with @preprintclub.bsky.social (www.biorxiv.org/content/10.1...) : 1/ Reviewers can distinguish quality and impact (+novelty in our model) 2/ Trainees want to review 3/ Authors love the experience

Bella Rauch@rauchlab.bsky.social · 9mo ago

Can we improve peer review? We think we can! Check out an experiment I helped with as part of @solvingforsci.bsky.social 's mission to make science better. And if you don't want to read the whole bioRxiv manuscript, here's an overview of the main findings: solvingfor.org/news-posts-d...

Very exciting to finally see clinical data where viral mimicry provides survival benefits

Daniel De Carvalho@daniel-decarvalho.bsky.social · 9mo ago

This week, that idea reached patients: Viral-mimicry priming + anti-PD-1 in relapsed/refractory NK/T-cell lymphoma delivered 47.6% complete responses, 66.7% ORR, and ~50% 2-year OS, even after prior PD-1 failure (Huang, Cancer Discovery 2025).

Short, noncoding YRNA can activate pathological variants of the innate sensor RIG-I, causing autoinflammation and #lupus nephritis in mouse models. Learn more in #ScienceImmunology: https://scim.ag/43ewTiV

Local activation of mutant RIG-I by short noncoding Y-RNA in the kidney triggers lethal nephritis

Y-RNA activates RIG-I gain-of-function mutants in the kidney, causing lethal autoimmune diseases including lupus nephritis.

scim.ag

It was a great experience to present our latest work on cancer vaccines in front of an audience of TE experts

Fusion Conferences@fusionconf.bsky.social · 9mo ago

A fantastic gathering of researchers at #EREHD25 😊💜 We are grateful for all the insightful talks, lively discussions, and new collaborations that emerged over these past few days! Rosie has truly loved working alongside Ting, Tao, Kate & Hui on this wonderful meeting #FusionCommunity

Proud of our Yu-Chan Chih for receiving the Trainee Innovation Idea Award for his work on cancer vaccination 👏🥇

Y RNAs getting some of the recognition they deserve

Waggoner Lab@labwaggoner.bsky.social · 9mo ago

Y-RNA activates RIG-I gain-of-function mutants in the kidney, causing lethal autoimmune diseases including lupus nephritis @sciimmunology.bsky.social @unibonn.bsky.social www.science.org/doi/10.1126/...

Check out our latest in @cp-trendscancer.bsky.social where rockstar PhD student @laurarosenberg.bsky.social reviews cancer therapies known to induce innate immune responses through the reactivation of Transposable Elements.

Trends in Cancer@cp-trendscancer.bsky.social · 11mo ago

Viral mimicry in cancer therapy

Check out our review on the role of #retroelements and #viralmimicry during cancer treatment! @neoviral.bsky.social

Trends in Cancer@cp-trendscancer.bsky.social · 11mo ago

Viral mimicry in cancer therapy

America’s cancer research system is under threat in one of its most productive moments. www.nytimes.com/2025/09/14/m...

Trump Is Shutting Down the War On Cancer

nytimes.com

The Empire State can’t afford to fall behind. A group of scientists is launching NY-CURES to fight for state and city level investment in research.✊ 📢 Sign up & show Albany we stand UNITED for science. 👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social #AdvocateForScience #NYCURES

NY-CURES@nycures.bsky.social · 11mo ago

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

Latest from us: we detail the protocol we use to generate mRNA-LNPs and to study immune response in preclinical setting. link.springer.com/protocol/10....

Generation of Lipid Nanoparticle mRNA Vaccines and Evaluation of Antigen-Specific CD8+ T-Cell Responses

mRNA vaccines have revolutionized vaccine development against infectious diseases, as demonstrated by the rapid creation and deployment of vaccines for SARS-CoV-2. In this chapter, we present a protoc...

link.springer.com

🎉 Congrats to student extraordinaire @bhavyasighs.bsky.social who earned a scholarship from #CIHR AND got a paper accepted in the same week!

Another nice example of a host-acquired gene in poxviruses, which modulates the host immune response. dx.plos.org/10.1371/jour...

Viral piracy of host RNA phosphatase DUSP11 by avipoxviruses

Author summary Viruses face a critical challenge of disabling or avoiding host immune defenses. Cells typically recognize the presence of a virus through specific molecular markers, including triphosp...

dx.plos.org

www.science.org/doi/10.1126/...

Exogenous RNA surveillance by proton-sensing TRIM25

Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens...

science.org

More great content from @preprintclub.bsky.social @epelmanlab.bsky.social. This @biorxiv-immuno.bsky.social preprint from Liu et al. reports that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure.

Danny Saban@sabanlab.bsky.social · last yr.

Thank you @natrevimmunol.bsky.social and Preprint Club, University of Toronto, Alex Lac & ⁦‪Slava Epelman‬⁩ for reviewing our preprint! www.nature.com/articles/s41...