Radiologist agreement in mRECIST 1.1 reporting for mesothelioma is poor and misclassification reduces trial power, just published in Lung Cancer. Thanks to all in our group, especially to Joshua Roche and @kevingblyth.bsky.social www.lungcancerjournal.info/article/S016...

Discordance in pleural mesothelioma response classification and modelling of impact on clinical trials

Pleural mesothelioma (PM) is an aggressive thoracic malignancy associated with prior asbestos exposure. The diagnosis is often delayed due to subtle imaging features, which may be limited to minimal p...

lungcancerjournal.info

Delighted to see this published in Radiology: Cardiothoracic Imaging @rsnasky.bsky.social - important to continue to drive development in pleural imaging. Big thanks to all my coauthors and especially @kevingblyth.bsky.social

Full text link below to a review article just published in Current Pulmonary Reports on Non-Specific Pleuritis. A key topic for those interested in #mesothelioma evolution. Well done to first author Mark Neilly and thanks to our co-author and pathology colleague, Craig Dick 👏 rdcu.be/d9Fgg

Great to be in beautiful Edinburgh for the National #Mesothelioma Education Day 2025 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Dr Neil McGlinchey kicking off the meeting in fantastic setting at Royal College of Physicians

Looking forward to this tomorrow ⬇️ National #Mesothelioma Network Education Day ✅ New Management Guideline 🩻 New Staging (TNM 9) 📈 Review of Audit Performance (QPI) Plus Trials, Interventional Pain, Pleural Nursing & Horizon scanning …then, dinner with team 🎉🍷

Check out this interview with our #PREDICTMeso PI @kevingblyth.bsky.social discussing #mesothelioma; why it takes so long to develop, and what we at @predict-meso.bsky.social are doing to research and develop new treatments #MesotheliomaResearch #MesoORIGINS #CancerResearch #EarlyDetection

Kevin Blyth@kevingblyth.bsky.social · 2y ago

A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇 Why does meso develop decades after exposure? What are we doing in @predict-meso.bsky.social to develop new treatments? @uofglasgow.bsky.social @cruk-si.bsky.social @cancerresearchuk.org www.bbc.co.uk/sounds/play/...

A few mins of #Mesothelioma chat starts @1251 on BBC Scotland Lunchtime Live👇 Why does meso develop decades after exposure? What are we doing in @predict-meso.bsky.social to develop new treatments? @uofglasgow.bsky.social @cruk-si.bsky.social @cancerresearchuk.org www.bbc.co.uk/sounds/play/...

Lunchtime Live - 23/12/2024 - BBC Sounds

News updates from Scotland and beyond, plus all your lunchtime sport, travel and weather.

bbc.co.uk

Looking forward to talking #mesothelioma on BBC Scotland Lunchtime Live in a few minutes!

There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...

Article in @heraldscotland.bsky.social this week highlights a sad #mesothelioma story & ongoing research in PREDICT-Meso, IAMMED, Meso-SCAPE & excellent Hansen lab @predict-meso.bsky.social @djmurphylab2.bsky.social @cruk-si.bsky.social www.heraldscotland.com/news/2477596...

Deadly dust stole my husband: fears grow for asbestos crisis in Scotland's buildings

They met as teenagers, married young, raised their family and saved hard for the future.

heraldscotland.com

It was great to be part of the BTOG/MesoUK Essential Update meeting this week Topics included diagnostics, new Rx, CNS roles, legal, pleural Nice to see 2 current PhD students presenting 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Meso Network (Matt) 🧬 PREDICT-Meso (Mark) @btog.bsky.social @mesouk.bsky.social @uofglasgow.bsky.social

Very proud of Jenny Ferguson - PhD viva passed today! 🎉🥂 Her thesis on stratification of #respiratory disease covered 🫁 STRATIFY trial of #pleural staging in Lung Ca 🔬Predictive Markers in #MPE 🦠 Immune markers of severe #COVID19 🙏 R Bhatnagar, C Church & L Richmond! @uofglasgow.bsky.social

🟡 Recruiting now – PREDICT-Meso PPI Group People affected my mesothelioma to join a new PPI group to advise on all stages of mesothelioma research.   Message us or visit our website… www.researchforthefuture.org/studies/predict-meso

New paper from our group on body composition changes in #mesothelioma during chemo ⬇️ 💪 61.5% patients lost muscle 🧈 60.4% patients lost fat 🫁 Extreme thoracic muscle loss & total fat loss independently prognostic Funded by Asthma+Lung UK www.sciencedirect.com/science/arti...

The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma

Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopat…

sciencedirect.com

Kevin Blyth: management of mesothelioma effusion 🔹IPC vs pleurodesis = equivalent efficacy For pleurodesis: 🔹 Talc = most effective agent 🔹 Big drain no better than smaller ones 🔹 NSAIDs fine for analgesia (won’t limit pleurodesis) 🔹 Talc slurry as good as poudrage

@dean_fennell: 2L mesothelioma options 👉 (small) subset of non-epithelioid pts do very well with Vin 🟢 Gem+Ramucirumab = ⬆️ PFS ❓ Gem maintenance = ⬆️ PFS, but a bit forgotten 🟢 Platinum rechallenge RR 50% ❓Activity in immuno rechallenge, RR up to 50%

Improve your mesothelioma service by forming a network: the 🏴󠁧󠁢󠁳󠁣󠁴󠁿 experience by Matthew Tate 🟢 ⬆️ data completeness 🟢 ⬇️ non-biopsy cases 🟢 ⬆️ OS in non-epithelioid 🔺 OS benefit not solely due to arrival of immunotherapy @btog.bsky.social @mesouk.bsky.social

PREDICT-Meso: 🧐 How does inflammation evolve into malignancy? 🧐 Can we diagnose mesothelioma at pre-malignant stage? 👉 80 institutions, 16 countries 👉 x5 work streams Fantastic, ambitious, international, multi-faceted project @btog.bsky.social @mesouk.bsky.social

Matthew Tate presenting outcomes from the Scottish #Mesothelioma Network ⬆️ Overall Survival in Non-Epi cases ⬆️ Use of Immunotherapy ⬆️ OS in Non-Epi cases not receiving IO Mesothelioma networks should be developed across the UK

Was that a collective sigh of relief, I heard?

BTOG@btog.bsky.social · 2y ago

We have an early Christmas present for you all - we've extended the #BTOG25 abstract submission deadline! You now have until Monday 16th December 23:59 GMT - no further extension will be made. Definitely a gift you can open before December 25th! Full details www.btog.org/23rd-btog-an... #LCSM

On-call week for me at #QEUH Lots of Flu A! 🦠😷 Felt like every other patient today. Will be interested to see if the upward trend in last weeks numbers continues publichealthscotland.scot/publications...

Can you believe it, it’s almost December! This year we’re excited to bring you a #RespMas advent calendar! Every day we’ll open a window to reveal a paper worth reading! By Christmas we’ll all be on top of our Respiratory game! #medsky #pulmsky #lungsky #RespEd #RespIsBest

This is why we are all in this field…to see, and one day to be able to produce work like this. Patho-DBiT-seq www.cell.com/cell/fulltex...

Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues

Patho-DBiT enables spatial profiling of a range of RNA species (i.e., mRNA, microRNA, tRNA, splicing isoform, etc.) all at once in clinical formalin-fixed paraffin-embedded tissue with high sensitivit...

cell.com

Heading home after a fantastic #BTSWinter2024 Leaving energised and grateful for friends and the opportunity to talk #mesothelioma in the Plenary Scientific Symposium. Also excited for 2025 under our new BTS President!

This morning I presented results of the STRATIFY multi-centre trial of staging thoracoscopy for minimal pleural effusion in lung cancer. The prevalence of occult pleural mets was only 14%, thoracoscopy was safe & altered treatment plans. Paper coming soon! #BTSWinter2024 x.com/UKPleura/sta...

I'm very grateful to Asthma & Lung UK for the early support they provided to our now international #mesothelioma research program. Pump-priming is such an impactful strategy for grant-awarding charities x.com/IanJarroldAL...

Day 2 of #WinterBTS2024 started with a sunny walk in followed by presentation of STRATIFY results (pleural staging of Mini-PE). Next up is #mesothelioma presentation at Plenary Scientific Symposium 😬

This is starting now at #BTSwinter2024 in Windsor on 5th floor!

British Association for Lung Research@balrcommunity.bsky.social · 2y ago

If you are going to #BTSwinter2024 you cannot miss the joint BTS/BALR symposium: Joining the dots on Wednesday 27/11. Part one will focus on internal interactions: 8.30am in Windsor - 5th Floor. Come for the view, stay for the stellar 🌟 line up of speakers! 👇

For anyone attending the Winter BTS meeting next week, we're having a Meso-ORIGINS study investigators' meeting on Wed 27th Nov. 1230-130pm, Rutherford Room on L4. Come and join if you're involved or just interested! #mesothelioma