I am excited to share that our manuscript titled 'Defining the ESKAPE pathogen prophage repertoire with PHORAGER' is now available online as a preprint in BioRxiv! 🤩 (doi.org/10.64898/202...) Here we present PHORAGER, a Nextflow pipeline for the identification and quality assessment of prophages 🧬
Hannah Pye
@hannahvpye.bsky.social
Postdoc @ Quadram Institute Bioscience | Exploring bacteriophage solutions to combat AMR in surface waters 🌊🦠 (she/her) All opinions are my own.
If you’re at the Viruses of Microbes conference, interested in Pseudomonas or phage therapy, check out @hannahvpye.bsky.social ‘s poster no84. #VoM2026
Excited to share our latest publication from the PhageLand project which investigated the effects of a phage cocktail, designed for wastewater bioremediation, on Daphnia magna microbiome and life-history parameters! 🌊💧 enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Phage Cocktail Designed for Wastewater Bioremediation Has Limited Effect on Crustacean Filtrator Microbiome Diversity and Health
Phage cocktail designed for wastewater bioremediation is safe for freshwater filtrators. D. magna cultured with phages showed no significant changes in life-history parameters and minor shifts in the...
enviromicro-journals.onlinelibrary.wiley.com
I’m delighted to have been awarded with a grant to support this new and exciting project, which is a proud career milestone for me! 😆 I’m now recruiting a Project Scientist to help on this project 🐷 Please see the recruitment advert below and apply via the link: shorturl.at/rIT8D
🆕Vacancy! We're looking for a Project Scientist to work on a project designing combinations of phages against Enterotoxigenic E. coli (ETEC) in swine. 💷 £29,890 🗓️ Apply by 16 November 2025 ➡️ buff.ly/Cq1dOf3
🆕 We’re looking for a motivated candidate to explore the role of phages in chronic respiratory disease to help make better decisions about phage therapy as a treatment 🫁 🗓️ Apply by 6 January 2026 ➡️ buff.ly/jkawqt7 @evelienadri.bsky.social
"I am trying to understand phages not just as agents of infection or therapy, but as participants in a vast biological dialogue." 💬 PhD student @deuskamya.bsky.social
Shades of Phage: The complexity of the biology of bacteriophages - Quadram Institute
PhD student Deus Dedit Kamya explains the nuances of biology bacteriophages and their potential for live-saving treatments
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Congratulations to the winners of the Microbial Genomics prizes at the Functional Multi-Omics Symposium organised by @yaasircheema.bsky.social. Best Poster Prize: Claire Hill Runner-up Best Poster Prize: Lizzi Coy Communication Prize Winner: Hannah Pye
🆕 Our scientists and those @johninnescentre.bsky.social are launching one of the first human trials of gene edited food, to understand whether biofortifying tomatoes in this way leads to higher levels of vitamin D in the blood after people have eaten them 🍅
Need a winter warmer? Groundbreaking gene-edited tomato soup trial with higher levels of 'Sunshine' vitamin recruiting now - Quadram Institute
Human trial of gene edited food, to understand whether biofortifying tomatoes in this way leads to higher levels of vitamin D in the blood
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Out yesterday. Using a translation reporter on a mini-tn5 transposon, and high freq. mutagenesis, we looked at translation on whole genome scale independently of genome annotation. academic.oup.com/nar/article/...
PIRT-Seq: a high-resolution whole-genome assay to identify protein-coding genes
Abstract. The advent of high-density mutagenesis and data-mining studies suggest the existence of further coding potential within bacterial genomes. Small
academic.oup.com
Applied Microbiology International (AMI) has launched a recruitment drive for Junior Editors and Junior Reviewers as part of its mission to nurture early career talent. Read more: www.the-microbiologist.com/news/ami-to-... Download full details and apply: appliedmicrobiology.org/about/our-te...
AMI to recruit second cohort of Junior Editors and Reviewers
Applied Microbiology International (AMI) has launched a recruitment drive for Junior Editors and Junior Reviewers as part of its mission to nurture early career talent.
the-microbiologist.com
Looking forward to presenting the latest results from the PhageLand project during the ‘Phages in Health and Remediation’ session at 4.30pm in Brown 1&2 at @femsmicro.org #FEMS2025 #phagesky #microsky
New pre-print alert! 🚨🫁 COPD affects millions worldwide. While we know bacterial dysbiosis drives disease, the role of bacteriophages remains unexplored. We re-analysed 135 COPD metagenomes to characterise the lung virome for the first time 🫁 1/9 www.biorxiv.org/content/10.1...
biorxiv.org
The MHRA today released new guidance for #Phage therapy in the UK. This will provide direction for scientists and researchers working to make this treatment a reality for patients. 🔬 🧪 🔗 www.gov.uk/government/n...
From probiotics to bacteriophages, our new themed collection 'Mitigation of Resistance and Alternatives to Antimicrobials' aims to explore novel, sustainable solutions to combat microbial infections. 💊 #AntimicrobialResistance #AMR Learn more here 👉 academic.oup.com/jambio/pages...
🆕 Vacancy! We’re looking for a Research Scientist to join Dr @evelienadri.bsky.social 's group to study bacteriophages, drug resistance and genetic evolution of Salmonella 🦠 💷 £36,720 to £39,750 🗓️ Apply by 2 July 2025 ➡️ buff.ly/7M2mDaa
This is a fantastic opportunity for a new post-doc to join our group at the Quadram Institute Bioscience!😀 #phagesky #microsky
🆕 Vacancy! We’re looking for a Research Scientist to join Dr @evelienadri.bsky.social 's group to study bacteriophages, drug resistance and genetic evolution of Salmonella 🦠 💷 £36,720 to £39,750 🗓️ Apply by 2 July 2025 ➡️ buff.ly/7M2mDaa
🧬🐄 NEW PREPRINT: Really happy to finally share the last big piece of work from my PhD! Spoiler: Cows are great and so are their viromes 🧵1/13 www.biorxiv.org/content/10.1...
Life-Stage Transitions Drive Distinct Gut Viral Communities in Dairy Cattle
Ruminant gut microbial communities profoundly influence host health and environmental impacts, yet their viral components remain poorly characterised across developmental transitions. Here, we analyse...
biorxiv.org
VACANCY: Postdoctoral Researcher in #Metagenomics. Working on a multi-centre UK collaboration, this role will look at how #soil #microbes establish, contribute and maintain healthy, biodiverse macro- & micro-communities. 📆 Apply by: 08 June 2025 ➡️
Postdoctoral Research Scientist in Metagenomics
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Fabulous talk (as always!) from @ryancook94.bsky.social about the Good, Bad and Ugly in Viromics at #microbio2025!
Please go check out poster B070 #Microbio2025 by @deuskamya.bsky.social on understanding phage resistance development in Klebsiella
Come and learn about prophages of Ruminococcus gnavus from @xenadyball.bsky.social at poster B078 #Microbio2025
If my flash talk earlier during the Infection Forum at #microbio2025 peaked your interest in our Bronchophage study, then please come and find me at my poster this afternoon (B286)! @microbiologysociety.org
Check out poster B286 #microbio2025 by @hannahvpye.bsky.social who is presenting the BronchoPhage study in which we are developing a phage-based therapy for bronchiectasis. Hannah also gave a great flash talk!
We had a great time representing @quadraminstitute.bsky.social at Norwich Science Festival! ✨ Our ‘Fantastic Phages!’ stall had lots of great engagement! It was exciting to share our passion for bacteriophages and their ‘superhero’ qualities with the public 🦸🦠
🚨Spring 2025 Updated Microbiome Informatics Webinar Series starts tomorrow Feb. 25!🚨 Free to attend, join us to learn with leaders in the field. More info and registration: coms.osu.edu/webinars/mic...
'Eco-Friendly Microbial Technologies for Water Treatment and Supply' is open for submissions! This collection aims to showcase cutting-edge research, case studies, and reviews that highlight the power of microbes in transforming water processes. 🌊 #SDG6 ow.ly/Q8FV50V2Rfp
Interested in microbiome and Salmonella? Then apply for our summer vacation bioscience research scholarship project: “Niche competition between pathogens and microbiota in the gut” tinyurl.com/33upx4bc @quadraminstitute.bsky.social @drrobkingsley.bsky.social
Project 20 - Niche competition between pathogens and microbiota in the gut
University of East Anglia
tinyurl.com
MicrobesNG POPUP Conference is coming to Norwich! It's a FREE #MicrobialGenomics conference 3rd Jul ECR's submit your abstract (talk or poster) by 3rd Apr www.surveymonkey.com/r/POP_UP_NOR Please repost! Organised with @getgenome.bsky.social & @norwichmicro.bsky.social #MNGPopUp #ECR #MicroSky
It was great to be interviewed about our latest publication ‘Phage Diversity in One Health’. In the interview we discussed the importance of expanding phage diversity to support One Health! 🌍 Read the full interview below ⬇️
Dr. Hannah Pye and Dr. Evelien Adriaenssens discuss expanding phage diversity to enhance #OneHealth. Their insights on overcoming challenges in isolation methods & exploring underutilized ssDNA & RNA phages, and more. #phagetherapy #IDsky #Medsky www.contagionlive.com/view/expandi...
Today is International Day of Women & Girls in Science. Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM