New publication: "Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner" is out now in JLB. MD/PhD student Anders Lindstedt led with an assist from @lab-williams.bsky.social. academic.oup.com/jleukbio/art... @cfi-umn.bsky.social 🧪

Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner

RNA sequencing and functional assays demonstrate that both LynA and LynB restrict macrophage proliferation and drive TLR-induced ECM remodeling and inflamm

academic.oup.com

New review with @lab-williams.bsky.social out today! One of the most enjoyable things about being a new PI has been making new collaborations and seeing projects advance through the pipeline. link.springer.com/article/10.1...

Mechanisms of Innate Immune Modulation by High-Fat Diet: Implications for Obesity and Asthma - Current Allergy and Asthma Reports

Purpose of the Review The innate immune system plays a critical role in mediating many of the physiological consequences of high-fat diet consumption. Dietary lipids, and specifically saturated fatty ...

link.springer.com

Registration is live for #AIC2025! Stay tuned for more updates and highlights of things to come at this year's meeting! www.autumnimmunologyconference.org

Autumn Immunology Conference | AIC2025

AIC is an annual conference in Chicago IL., featuring plenary sessions presented by outstanding Immunologists as well as offering a forum for students and trainees to present their latest findings in ...

autumnimmunologyconference.org

Please share! Recently finished your PhD or plan to in 2025, and love immunology or vascular biology? We're recruiting a #postdoc @immunologyau.bsky.social Join our team! More info here: rb.gy/howgk4

Williams Lab had a great time at the Atherosclerosis Gordon conference- amazing talks and a great chance to reconnect with leading researchers from around the world. Looking forward to doing this again!

Our latest paper, Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages, is online at Communications Biology. Collaboration with the Ivanov and Revelo labs. @cfi-umn.bsky.social rdcu.be/esUdT

Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages

Communications Biology - Transcriptional analysis of lipid associated macrophages across chronic inflammatory diseases and tissues reveals shared and tissue-restricted gene expression programs.

rdcu.be

Promoted to Associate Professor with tenure, University of Minnesota Medical School! 🎉🍾

Made it to AAI Hawaii 🏝️! I’m speaking in the NIAID symposium on “Sex Differences in Inflammation and Autoimmunity” on Monday May 5, Room 313C.

Getting out with the lab to celebrate some recent successes! A great day in Minneapolis

So thrilled to have @lab-williams.bsky.social visit the @ImmunologyAU for an amazing overview of Trem2 in atherosclerosis! @lynnhedrickau.bsky.social

Our first Postdoc joined this week - welcome Gage! Lab is getting pretty tight. Maybe time for the CFI to give us a little more space!!!

Another great year in the Williams Lab! Today we celebrated Hannah’s new AHA predoc fellowship (congrats!) and the end of Lisa’s rotation. More to come in 2025!! 🎄🧬🔬👨‍🔬

Great to have met up with old friends from my Postdoc at WashU - Kiwook Kim (UIC) and Tyler Ulland (Wisconsin).

Esther Lutgens (Mayo) and I wrote a News & Views ( rdcu.be/d1S5x ) covering a recent NCVR paper that highlights immune checkpoint pathways in atherosclerosis- original paper. www.nature.com/articles/s44...

Unrestrained cancer immunity ignites atherosclerosis

Nature Cardiovascular Research - Researchers map the expression of immune checkpoints and cell interactions within human atherosclerotic plaques, and the influence of relevant comorbidities such as...

rdcu.be

Ready for the UMN MICaB recruitment table at the Autumn Immunology Conference undergraduate session! 👩‍🔬👨‍💻👨‍🔬👩‍💻🧪🧬🔬🧫

Williams Lab @ Autumn Immunology Conference 2024