Can we rewire how plants fight disease? We used AF3 to predict, validate, and engineer a sensor–helper interface that escaped biochemistry for years 🤯 Grateful to @mpcontreras.bsky.social & @kamounlab.bsky.social for trusting me to be part of this story. Full story below👇🏻

Mauricio Contreras@mpcontreras.bsky.social · 3mo ago

Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇

Check out our updated activation-and-release model. This one image condenses over 10 years of work from many legendary @kamounlab.bsky.social members 🤯 Big shoutout to Chih-Hang, @tolgaboz.bsky.social, Lida, Aki, Selvaraj, @jmadhuprakash.bsky.social, @hsuanpai.bsky.social, Ben and many more!

Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇

bioRxiv Plant Bio@biorxiv-plants.bsky.social · 3mo ago

A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1

A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1

AI-guided discovery of atypical protein assemblies https://www.biorxiv.org/content/10.64898/2026.05.03.722499v1

AI-guided discovery of atypical protein assemblies https://www.biorxiv.org/content/10.64898/2026.05.03.722499v1

Thanks Mati! This is the result of teamwork and the incredible support I had along the way 💪🏼

@maticapella.bsky.social · last yr.

Double celebration! 🎉🎉🎉 On the same day, Main Garro obtained her diploma and her first paper accepted! Congratulations!!! Extremely happy to be a small part of her scientific career!!! 🧬👩🏻‍🔬

Double celebration! 🎉🎉🎉 On the same day, Main Garro obtained her diploma and her first paper accepted! Congratulations!!! Extremely happy to be a small part of her scientific career!!! 🧬👩🏻‍🔬

I'm a Biotechnologist and I couldn't be happier! 🥳 Eternally grateful to the university for my education and to my family & friends for their support 🥹❤️

📣 Thermomorphogenesis community 📣 I’m very excited to announce our next JC: Matías Capella (@maticapella.bsky.social) will present his preprint on DNA methylation in thermomorphogenesis. Don't miss out!!