Revolutionising notifiable avian disease diagnostics: validation of direct swab testing for Avian Influenza and Newcastle disease using the CENOS platform https://www.biorxiv.org/content/10.64898/2026.08.11.744268v1

Metformin modulates autophagy in heterozygous and CRISPR-edited TSC2 primary fibroblasts https://www.biorxiv.org/content/10.64898/2026.08.11.743350v1

PPAR-γ/PCK1 metabolic pathway modulate synovitis and fibrosis in KOA rats https://www.biorxiv.org/content/10.64898/2026.08.05.742949v1

SAD-6/ATRX enables broad genome surveillance and defense in fungi https://www.biorxiv.org/content/10.64898/2026.08.11.744009v1

Investigating the significance of iron levels in influencing megakaryocytic commitment in megakaryocyte-erythroid progenitors https://www.biorxiv.org/content/10.64898/2026.08.11.743878v1

Tethering-mediated recruitment of pioneer factors by NuRD enables signal dependent gene activation and protects cell identity https://www.biorxiv.org/content/10.64898/2026.08.11.744124v1

Reprogramming Cas9 PAM Recognition for Allele-Specific Editing https://www.biorxiv.org/content/10.64898/2026.08.10.744034v1

Integrated sequencing approach to probe rRNA modification landscape during human embryonic stem cell differentiation https://www.biorxiv.org/content/10.64898/2026.08.10.743918v1

Use of photocaged molecular oxygen for time-resolved serial X-ray crystallography https://www.biorxiv.org/content/10.64898/2026.08.10.743912v1

CRISPR/Cas9-mediated transformation enables functional characterization of the effector Avr4 in the banana pathogen Pseudocercospora fijiensis https://www.biorxiv.org/content/10.64898/2026.08.10.742443v1

Structural evolution of a yeast amyloid in vivo is shaped by chaperones https://www.biorxiv.org/content/10.64898/2026.08.10.743537v1

Species-specific susceptibility and low transmission of the historical Japanese encephalitis virus Nakayama strain in North American Culex mosquitoes https://www.biorxiv.org/content/10.64898/2026.08.10.744046v1

Dual-site specificity of the archaeal tRNA m2G methyltransferase Trm14 https://www.biorxiv.org/content/10.64898/2026.08.09.743744v1

Plasma titration provides a physical ruler for cross-platform proteomics https://www.biorxiv.org/content/10.64898/2026.08.09.740864v1

Pseudouridines in the U2 Branch Site Recognition Region Differentially Contribute to Branch Site Recognition during Pre-mRNA Splicing https://www.biorxiv.org/content/10.64898/2026.08.09.743773v1

Evolution of mechanical chromatin insulators from selfish genetic elements https://www.biorxiv.org/content/10.64898/2026.08.08.743475v1

A ligand-property-guided computational framework for prioritizing de novo protein binders for small molecules https://www.biorxiv.org/content/10.64898/2026.08.08.743643v1

Ficd loss rescues motor impairments and reverses oligodendrocyte maturation deficits in a mouse model of spinocerebellar ataxia type 3 https://www.biorxiv.org/content/10.64898/2026.08.07.743629v1

Oral administration of dibenzoylmethane (DBM) prevents cognitive decline in a C9ORF72-mediated FTD mouse model https://www.biorxiv.org/content/10.64898/2026.08.07.743573v1

NET1 mRNA localization to the midbody is required for ARP2/3-dependent initiation of mitotic abscission https://www.biorxiv.org/content/10.64898/2026.08.07.743554v1

Mechanistic assessment of eDNA passive samplers: a case study with invasive freshwater bivalves https://www.biorxiv.org/content/10.64898/2026.08.07.743527v1

Protein expression of short-chain dehydrogenases/reductases and their inducibility by flubendazole in Haemonchus contortus https://www.biorxiv.org/content/10.64898/2026.08.07.743491v1

Intra-host IRES heterogeneity shapes hepatitis C virus translation through epistatic and population-level effects https://www.biorxiv.org/content/10.64898/2026.08.05.743084v1

Improving metazoan biodiversity inventories associated with rocky subtidal habitats of the North Colombian Pacific through eDNA metabarcoding and DNA barcodes https://www.biorxiv.org/content/10.64898/2026.08.06.743172v1

A starvation-remodeled pre-mRNA structure controls U1 recruitment and nutrient-stress adaptation in yeast https://www.biorxiv.org/content/10.64898/2026.08.06.743327v1

Beyond DNA barcodes: an open-source workflow for recovering and organizing barcoded vouchers for ecological and evolutionary research https://www.biorxiv.org/content/10.64898/2026.08.06.743289v1

Sequential HIV-1 fusion protein gates control the initiation of host cell entry https://www.biorxiv.org/content/10.64898/2026.08.06.743292v1

Novel ddPCR diagnostic assays for the high-throughput surveillance of Kdr mutations in Aedes albopictus https://www.biorxiv.org/content/10.64898/2026.08.06.743222v1

NAMPT activation uncovers a senescence-specific vulnerability and promotes healthy aging in combination with NAM https://www.biorxiv.org/content/10.64898/2026.08.06.743365v1

Why architecture matters: Controlling gene expression through design https://www.biorxiv.org/content/10.64898/2026.08.06.743186v1