Systematic review and meta-analysis: Targeted and immune-based therapies showed clinically meaningful activity in #CutaneousTCellLymphoma, with differences in response, durability, and toxic effects across therapeutic cohorts. ja.ma/4iignFi
JAMA Dermatology
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JAMA Dermatology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. đ JAMADermatology.com
In multisite #MucousMembranePemphigoid, fewer than half of patients achieved simultaneous remission across all involved sites, with persistent oral and ocular disease most often limiting overall disease control. ja.ma/3WByCON
In patients with drug reaction with eosinophilia and systemic symptoms, interleukin 5 inhibitors plus corticosteroids were associated with faster steroid taper and eosinophilia resolution vs corticosteroids alone. ja.ma/4dPnMdT
Interleukin 5 Inhibitors and Steroid-Sparing Effects in Drug Reaction With Eosinophilia and Systemic Symptoms
This cohort study examines the steroid-sparing potential and safety profile of interleukin 5 inhibitors for drug reaction with eosinophilia and systemic symptoms.
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Several #Melanoma risk prediction models discriminated reasonably well in an independent Australian cohort, but most underestimated absolute risk. ja.ma/4yE7Wuj
đ This case report describes coalescent verrucous plaques and nodules with thick dark-brown crusts on a mildly erythematous base and granulomatous inflammation with pigmented septate hyphae in the dermis without sclerotic bodies. ja.ma/4yyGVs2
Refractory Phaeohyphomycosis Due to CARD9 Variants
This case report describes coalescent verrucous plaques and nodules with thick dark-brown crusts on a mildly erythematous base and granulomatous inflammation with pigmented septate hyphae in the dermis without sclerotic bodies.
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In patients with #Rosacea receiving standard therapy, device-free #AuricularAcupressure improved Investigator Global Assessment treatment success vs sham acupressure and produced immediate vascular improvement. ja.ma/4yLxWVe
In patients with #LichenPlanus, oral, cutaneous, and genital cancer risks were increased vs the general population, especially when cancer occurred at the same anatomical site as the disease. ja.ma/4dEReTN
In patients with #LichenPlanus, oral, cutaneous, and genital cancer risks were increased vs the general population, especially when cancer occurred at the same anatomical site as the disease. ja.ma/4hRKEuj
Among children of #Melanoma survivors, a telehealth behavioral intervention did not reduce sunburn over time vs an active control, but it was associated with lower child-reported sunburn immediately postintervention and better #SunProtection behaviors. ja.ma/4ymSP8r
đŹ Editorial: In advanced #MycosisFungoides and #SĂ©zarySyndrome, the Cutaneous Lymphoma International Prognostic Index may help identify patients at diagnosis who need closer monitoring, different treatment intensity, or clinical trial consideration. ja.ma/4s6v6rp
A 1-time hydrocolloid dressing may be a safe, convenient option after skin surgery, according to a randomized clinical trial in JAMA Dermatology. #Dermatology #SkinSurgery đ Learn more: ja.ma/3TfRrpF
Among children of #Melanoma survivors, a telehealth behavioral intervention did not reduce sunburn over time vs an active control, but it was associated with lower child-reported sunburn immediately postintervention and better #SunProtection behaviors. ja.ma/4rTrMzH
đŹ Editorial: In advanced #MycosisFungoides and #SĂ©zarySyndrome, the Cutaneous Lymphoma International Prognostic Index may help identify patients at diagnosis who need closer monitoring, different treatment intensity, or clinical trial consideration. ja.ma/4yFgKRo
Among children of #Melanoma survivors, a telehealth behavioral intervention did not reduce sunburn over time vs an active control, but it was associated with lower child-reported sunburn immediately postintervention and better #SunProtection behaviors. ja.ma/4hLlP3j
Can a blood test help detect Merkel cell carcinoma recurrence? A JAMA Dermatology study suggests that tracking polyomavirus antibody titers after surgery may be used to monitor for cancer recurrence. #SkinCancer #MCC #cancerresearch đ Read full article to learn more: ja.ma/4xKJ4Aq
Listen to Keith A. Choate, MD, PhD, discuss his JAMA Dermatology article which investigates how longitudinal growth patterns in children with epidermal differentiation disorders vary by genotype with Adewole S. Adamson, MD, MPP. ja.ma/4hP2lvP
Among 2 patients with refractory #Pemphigus, B-cell maturation antigenâtargeted T-cell engager therapy was associated with rapid B-cell depletion, desmoglein antibody loss, and remission of clinical disease activity. ja.ma/4yoQt9O
In the Veterans Health Administration, #PseudofolliculitisBarbae diagnosis was most prevalent among Black male and Black female veterans, with substantially higher prevalence than among White veterans. ja.ma/3VhJHEg
For pediatric patients aged â„4 to <12 years with #HairLoss, international expert consensus supports #LowDoseOralMinoxidil for selected hair follicle, hair cycle, and hair shaft disorders, with structured dosing and reassessment guidance. ja.ma/4jyh1AF
Low-Dose Oral Minoxidil Use for Pediatric Hair Disorders
This international Consensus Statement seeks to establish international expert consensus on recommendations for use of low-dose oral minoxidil to treat pediatric patients with hair disorders.
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Among children with #EpidermalDifferentiationDisorders, growth impairment was genotype specific and most evident early in life, with persistent height deficits in SPINK5 and attenuation of early deficits in ABCA12 and KRT10. ja.ma/4hmMpko
Can 3-dimensional total-body photography improve #melanoma detection? đ Read the article to learn more: ja.ma/4xJCSJ1
3D Total-Body Photography in Patients at High Risk for Melanoma
This randomized clinical trial compares usual care to usual care plus 3-dimensional total-body photography and sequential digital dermoscopy imaging for early detection of skin cancer in patients at high risk of melanoma.
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Elephantiasic #PretibialMyxedema can present with marked lower-extremity swelling, nodular hyperplasia, and toe clubbing in patients with Graves disease. ja.ma/3TeDLuZ
For #PseudofolliculitisBarbae, expert consensus supports behavioral modification of hair removal practices as first-line therapy, with topical, systemic, and laser-based treatment options also recommended. ja.ma/4d2516E
đŹ Editorial: Permanent hair removal may be medically necessary gender-affirming care for transgender women and nonbinary individuals assigned male at birth when #Hirsutism contributes to gender dysphoria, misgendering, and reduced quality of life. ja.ma/4yekVn5
Among adults with cutaneous #LichenPlanus, ruxolitinib cream reduced lesions and itch vs vehicle cream and no serious treatment-emergent adverse events were observed. ja.ma/3TlD4Qn
In a qualitative study of transgender women and nonbinary adults assigned male at birth, #Hirsutism was associated with stigma, social and romantic isolation, and gender dysphoria, and many participants described extensive efforts to conceal visible hair. ja.ma/47gzSZI
In patients with #HidradenitisSuppurativa, #Interleukin17 inhibitors were not associated with a significant increase in inflammatory bowel disease risk vs placebo, and events were rare. ja.ma/46dYTo8
#Omalizumab for #ChronicUrticaria showed a median drug survival of 3.1 years, with treatment most often discontinued after disease control, supporting its sustained real-world benefit. ja.ma/4gTW3tc
This case report describes a patient with a history of myasthenia gravis and thyoma who developed upper extremity myalgias and arthralgias after tapering prednisone. ja.ma/4x9ijGt
Coverage for #AtopicDermatitis specialty therapies varied widely across commercial payers, and most policies required step therapy beyond US Food and Drug Administration labeling. ja.ma/469Tyhk