Amandine Viau, Joran Martin and I had a very nice meeting @club-cfc.bsky.social in Aussoy where we could present our recent works @institutimagine.bsky.social in the @theracilproject.bsky.social ! Congrats to Joran who won the best talk price! #cilia #ciliopathies #nephronophthisis #kidney
Institut Imagine
@institutimagine.bsky.social
🔬 Premier centre européen dédié aux maladies génétiques. 📍 Campus Necker - Enfants Malades, Paris | #Recherche #Santé #Innovation 🌐 www.institutimagine.org
🔴 Happening now at Institut Imagine: Prof. @danmucida.bsky.social (Rockefeller University, HHMI) on how immune cells and the gut lining talk to each other, and how the brain senses what's happening in the gut, from infection to inflammation. #Immunology #Neuroimmunology
One bold idea can change everything. Paul Bastard is leading team ATLAS to explore whether autoantibodies also influence cancer risk. Read Paul’s full interview at bit.ly/4A4Og4B 📹 Includes footage from @institutimagine.bsky.social
🔴 Happening now at our Monday Seminar: Prof. Xavier Roca (NTU Singapore) on "Diagnostics of mutations affecting splicing in genetic disease." Exploring two decades of splicing biology, from mechanisms to variant interpretation & rare disease therapeutics. 🧬 #InstitutImagine #Genetics
Come and join us in building an exciting new mitochondrial cell biology lab in Paris! 🚀 📅 Start: Nov–Dec 2026 ⏳ Deadline: 2 Oct 2026 #Mitochondria #Postdoc #CellBiology #mtDNA #Microscopy #Paris
🔬 Laboratory Manager We’re looking for a scientist with a strong molecular/cell biology background to help run and develop the lab while contributing experimentally to our research. 👉 Apply: www.welcometothejungle.com/fr/companies...
Lab Manager - Institut Imagine - CDD / Temporaire à Paris
Institut Imagine recrute un(e) Lab Manager à Paris !
welcometothejungle.com
👉 Apply for the Postdoctoral positions: www.welcometothejungle.com/fr/companies...
Two (2) Postdoctoral Positions in Mitochondrial Cell Biology - Institut Imagine - CDD / Temporaire à Paris
Institut Imagine recrute un(e) Two (2) Postdoctoral Positions in Mitochondrial Cell Biology à Paris !
welcometothejungle.com
🧬 Two postdoc projects: 1️⃣ Inner mitochondrial membrane quality control & mtDNA dynamics 2️⃣ Golgi-derived vesicles, membrane contact sites & mitochondrial dynamics 📅 Start: Nov–Dec 2026 ⏳ Deadline: 2 Oct 2026
Our lab studies how mitochondrial membrane dynamics, mtDNA biology and inter-organelle contact sites regulate mitochondrial function and cellular homeostasis. We combine cell & molecular biology with cutting-edge live-cell and high-resolution microscopy. 🔬
🚀 We’re hiring! Join our newly established lab at the @institutimagine.bsky.social in Paris 🇫🇷 We’re recruiting: 🧬 2 Postdoctoral Researchers in Mitochondrial Cell Biology 🔬 1 Laboratory Manager Thread below 👇
Congratulations to Damien Glon and Quentin Riller on this fruitful collaboration between Yves Gaudin's team @cnrs-paris-saclay.bsky.social and our team @institutimagine.bsky.social . www.nature.com/articles/s41...
NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates - Nature Communications
TBK1 kinase is a key regulator of type I interferon production and upon activation the TBK1adaptor proteins are known to form liquid condensates. Here the authors show NAP1 is a rheostat, switching fr...
nature.com
The #ISDN2027 symposium on molecular drivers of stability versus #plasticity of neural cell fate and their implication for #brain repair will be completed by @sarabiz86.bsky.social from @institutimagine.bsky.social and Samir Vaid from @tudresden.bsky.social.
1/ We are excited to report in @PNASNews that autoantibodies neutralizing type I interferons underlie 35% of cases of Chikungunya virus (CHIKV) encephalitis or myelitis from a multiple cohort study. www.pnas.org/doi/10.1073/...
Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus encephalitis or myelitis | PNAS
Chikungunya virus (CHIKV) infection is typically not life threatening but may, in rare cases, affect the central nervous system (CNS). In three coh...
pnas.org
🔬 Severe pediatric IBD with no genetic cause? Research by Institut Imagine & Uppsala University shows ~2% of cases have autoantibodies neutralizing IL-10, the gut's inflammation brake. Standard tests miss them, but finding them guides targeted care. 🔗 doi.org/10.1136/gutj... #IBD
There is more than cilia beating in the establishment of left-right symmetry! Proud to have contributed to this beautiful study by Amaia Ochandorena Saa @meilhacsigolene.bsky.social where Thierry Blisnick imaged mouse node by SEM doi/10.1126/sciadv.adx6486 @pasteur.fr @institutimagine.bsky.social
"The ERC funding that I was awarded was instrumental for my team to be selected by the scientific board of Institut Imagine." More about Edor Kabashi's research @institutimagine.bsky.social 👉 buff.ly/AXKfPvA More about EU support for researchers who would like to #ChooseEurope 👉 buff.ly/Y62mN2e
#FOXP3 deep intronic variant underlying #IPEX. New report from Pierre Gaufryau, Marie-Claude Stolzenberg, Jérémie Rosain @jrosain.bsky.social et al. @hopitalnecker.bsky.social @institutimagine.bsky.social: rupress.org/jhi/article/... #Atopy #Diagnostics #Autoimmunity #InbornErrorsOfImmunity
🩸 Violent immune reactions (HLH) often hide blood cancer. Biopsies are risky, but a new 2-step blood test (cytokine ratio & score) from Hermine's team at Institut Imagine quickly identifies underlying lymphomas—meaning fewer invasive procedures and faster treatment. 🔗 doi.org/10.1002/ajh....
1/ We are thrilled to share our first @cellcellpress.bsky.social paper with the ATLAS team studying the role of antibodies, emphasizing autoantibodies in cancer (authors.elsevier.com/a/1nUSAL7PXy...).
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🔬 How do ADPKD cysts form? A JCI study by @hkd-l.bsky.social at Institut Imagine & Frank Bienaimé's group @inem-necker.bsky.social shows: without polycystin-1, the tubule sleeve gets softer, not stiffer. This loosening lets the tube expand. A new therapeutic target! 👏 📄 jci.org/articles/vie...
Why do some ‘super avoiders’ never develop cancer? Team ATLAS has launched its global effort to find out, supported by the Breast Cancer Research Foundation, the Susan Wojcicki Foundation, the Torrey Coast Foundation and @cancerresearchuk.org. ➡️ www.cancergrandchallenges.org/news/backing...
After 10 fantastic years at the @mrc-mbu.bsky.social, @cam.ac.uk, it is time for our lab to move to France!! I am delighted to announce that we will begin a new adventure at the @institutimagine.bsky.social in Paris in September 2026!!
🧠 What if Alzheimer's isn't just about neurons? A new Nature Neuroscience study from Michela Deleidi's team at Imagine shows stressed mitochondria cause microglia (brain immune cells) to age prematurely, disrupting neural connections. 📄 lnkd.in/gCg5qdRb
ADAR1 loss-of-function variants altering RNA editing define a new #interferon-dependent #psoriasis subtype. New study from Florence Assan, Hervé Bachelez @institutimagine.bsky.social and colleagues: rupress.org/jem/article/... #HumanDiseaseGenetics
Kicking off today's MAGIC meeting on "Development & Mechanics"! 🧬 First up: Audrey Desgrange (Institut Imagine) on the "Biomechanics of heart development." We're exploring how physical forces actively shape our most vital organ. ❤️🔬 🧵👇 #DevBio #Biomechanics #HeartResearch
📢 Happening Now: Weekly Monday Seminar! We are thrilled to welcome Prof. Aleixo Muise (University of Toronto & @sickkids.bsky.social sky.social) to Institut Imagine today. He is currently presenting: "Novel insights into Monogenic Intestinal Disease." #Genetics #Immunology #Research
🏅 Notre directrice générale, la Pr Bana Jabri, figure dans le palmarès 2026 du TIME France Health, parmi « Les 20 personnalités françaises qui font la santé » !
Congratulations to LS1 grantees @hecklab.bsky.social and Annarita Miccio at @institutimagine.bsky.social , for being awarded ERC POC grants! :)
The round 1 results of the 2026 ERC Proof of Concept Grant call are out! 🎉 182 researchers receive a total of €27.3 million to explore the commercial and societal potential of their ERC-funded findings. Read more 👉 buff.ly/K8GXgbs #ERCPoC #FrontierResearch @scienceinnovation.ec.europa.eu
We're live from the Future of Genetic Medicine Symposium today at Institut Imagine! 🧬 We are incredibly delighted to partner with @genethonfr.bsky.social & the Broad Institute's Center of Genetic Surgery for this event.
🔬 Kicking off our weekly MAGIC meeting! Our own Alice Lepelley is on stage sharing novel insights into type I IFN neuroinflammation driven by PTPN1 mutations in humans. 🧠🧬 #Neuroinflammation #Genetics #Interferon