🔍 Vague symptoms predict poorer outcomes in #PancreaticCancer 🔸StageIV disease was more frequent (62% vs 40%) 🔸Fewer received tumour-reductive treatment (34% vs 50%) 🔸Mortality risk remained 48% higher after adjustment Read more in UEG Journal: 👉 https://bit.ly/4A4aXWI

🛡️ Immunogenicity does not compromise outcomes with subcutaneous #infliximab 🔸Anti-drug antibodies (#ADAs) lowered drug levels but not 1-year efficacy or safety 🔸Treatment persistence remained similar regardless of ADA status Find out more in this UEG Journal article: 👉 https://bit.ly/3UESgZp

🧭 #Ustekinumab offers a safety advantage after #vedolizumab failure in #UC 🔸 Similar remission rates with infliximab, anti-TNF SC & ustekinumab 🔸 Fewer adverse events and treatment discontinuations with ustekinumab Read the full article in UEG Journal: 👉 https://bit.ly/4gPXeKa

⚖️ #Subcutaneous infliximab achieves higher tissue drug levels in #IBD 🔸Higher serum & tissue infliximab levels vs #IV therapy 🔸Tissue levels correlated with sustained remission and predicted outcomes better than serum levels Read the article in UEG Journal: 👉 https://bit.ly/4yuoyoB

UEG Week behind the scenes with UEG Executive Director @moestl.bsky.social​ 📹 After more than 20 UEG Weeks, which moment still gives Doris goosebumps? And what does it really take behind the scenes to bring a congress of this scale to life? Watch this short interview to find out 👇

✂️ Selective surgery is key in managing intraductal papillary mucinous neoplasm 🔸61% had surgery without prior surveillance 🔸5-year OS excellent across LGD, HGD & T1a-b lesions 🔸T1c cancer & age≥75 predicted long-term mortality Read the article in UEG Journal: 👉 https://bit.ly/4iHrF7N

🧠Psychological factors predict response to a low FODMAP diet in #IBS 🔸Lower GI-specific anxiety → better symptom response 🔸Higher treatment expectancy → improved symptoms & QoL 🔸Positive illness perceptions →better outcomes Read the full article in UEG Journal 👉 https://bit.ly/4xvGIG7

🦠 This population-based programme invited adults aged 30–34 years to undergo H. pylori screening and treatment, aiming to support gastric cancer prevention through early eradication of this well-established carcinogen Read the article in UEG Journal 👉 https://bit.ly/3TsuzTw

🧬 Microlithiasis may trigger acute pancreatitis through NLRP3-driven papillitis This new study uncovers a potential mechanism linking biliary microlithiasis to acute pancreatitis, even in the absence of duct obstruction Read the full article in UEG Journal 👉 https://bit.ly/3S1eP9C

🔬 Intestinal barrier healing predicts sustained remission in ulcerative colitis This prospective study of 81 patients used probe-based confocal laser endomicroscopy (pCLE) to assess intestinal permeability & microscopic inflammation More in UEG Journal 👉 https://bit.ly/3U48pXN

🛠️ New prospective data from the PROTECT registry show that early-career endoscopists can achieve high efficacy and safety in EUS-guided gastroenterostomy (EUS-GE) using the WEST technique under structured supervision Read the article in UEG Journal 👉 https://bit.ly/3RKhcxt

❄️Cold resection techniques match hot EMR for 10–20mm #SSLs 🔸Cold snare polypectomy(CSP) & cold EMR achieved non-inferior resection vs hot EMR 🔸CSP reduced procedure time 🔸Submucosal injection improved en bloc resection & margin Read more in UEG Journal 👉 https://bit.ly/4yNnMnl

🧒 #Steroid use remains high in children with #IBD despite modern therapies 🔸 Steroid use ↓ in #CD 🔸 No reduction in #UC over 15 years 🔸 Highest exposure in the 1st year after diagnosis 🔸 Hospitalization ↑ risk of excess use Learn more in UEG Journal: 👉 http://bit.ly/4uSsLR0

⚠️ Registering for UEG Week 2026? Watch out for scams. Fake websites and lookalike emails are targeting attendees during registration season. Before you enter any payment details, swipe through for our quick safety checklist ⬇️

🎯 #FIT and #colonoscopy provide comparable #ColorectalCancer screening outcomes across sex & age groups 🔸 FIT → higher participation 🔸 Similar CRC incidence & mortality reduction 🔸 Colonoscopy detected more premalignant lesions Learn more in UEG Journal: 👉 https://bit.ly/3RDSXR0

🦠 #PancreaticCancer is linked to distinct oral & duodenal #microbiome signatures 🔸↓Duodenal microbial diversity in #PDAC 🔸Oral-duodenal taxa overlap supports microbial migration 🔸Higher salivary diversity → longer survival Access the article in UEG Journal: 👉 https://bit.ly/3RlQomF

🔥 Asymptomatic Walled‐off #PancreaticNecrosis (WOPN) often requires intervention within 1 year 🔸 ~60% needed intervention 🔸 Most events within 100 days 🔸 Infection & pain most common 🔸 Size predicts risk (>5.6 cm) Read more in UEG Journal: 👉 https://bit.ly/4duoFr6

Thank you to everyone who joined us in Vienna for the joint meeting of National Societies Forum & Meeting of Members! From interactive workshop sessions to strategic exchanges – your engagement & insights are what drive the UEG community forward. Until next time! 💚 #weareUEG

🧬 Genetic testing does NOT replace surveillance in #PancreaticCancer Prospective study (n=500) 🔸 Pathogenic variants in 8.8%; 3.4% high-penetrance 🔸 ~50% carriers missed by current criteria 🔸 Cancer can occur without mutations Learn more in UEG Journal: 👉 https://bit.ly/4duoufq

In part 2 of our MASLD series, Sven Francque outlines that resmetirom is now approved in F2-F3 fibrosis in parts of Europe, semaglutide has produced positive phase 3 data in MASH, and the guideline is being updated. Tune in now: 🔗 https://bit.ly/44R97K3

This #DigestiveHealthMonth, we’ve taken a closer look at one of Europe’s most pressing public health challenges – the growing burden of digestive diseases and cancers 📊 – and what the evidence tells us about how to respond 👇

On #WDHD2026, listen to our recent policy webinar exploring whether the EU Safe Hearts Plan can improve digestive health – and the changes needed to drive progress on prevention. Watch the full discussion on YouTube: https://bit.ly/3Rb2vTx or Gutflix: https://bit.ly/4fn17Hi

#WDHD2026 marks a moment – but not the end of the conversation. What follows matters. Hear from @joostphdrenth.bsky.social​​ and Roos E. Pouw on what must happen next – ensuring evidence drives real change to reduce the burden of digestive diseases & cancers across Europe 🛡️

UEG President Joost P.H. Drenth is at #EASLCongress 2026 to celebrate a truly outstanding congress – and to remind everyone: the GI and hepatology community will be back in Barcelona for #UEGWeek in October ➡️ https://ueg.eu/week @easlnews.bsky.social​ @joostphdrenth.bsky.social​

Today is World Digestive Health Day! 🌍️ This year's theme, 'Chronic Diarrhea: Don't Flush the Signs Away,' is a call to recognise symptoms, break stigma and act early. Learn how to avoid common mistakes in diagnosis and treatment to support better care: https://bit.ly/4tOzRWg

Patient voices must sit at the heart of digestive health strategy 💬 Our manifesto outlines actions to drive meaningful change across: Digestive cancer care 🎗️ Patient-reported outcomes (PROMs) 📊 Patient involvement in clinical trials 🧪 Learn more 👉 https://ueg.eu/a/380

Around 30% of adults have steatotic liver disease. Which ones actually need a hepatologist? In part 1 of our MASLD series Sven Francque outlines the new nomenclature, why BMI is the wrong lens, and how FIB-4 should drive your referral decisions. 🔗 https://bit.ly/44R97K3

💪 A stronger future for digestive cancer screening starts here. Our new position paper sets out a strategic path forward – translating evidence into action to strengthen screening for gastric, colorectal, liver and pancreatic cancers. Explore more 👉 https://bit.ly/4mYFleR

Transforming Europe’s food systems requires coordinated action 🤝 From front-of-pack labelling to fiscal measures, reformulation and marketing restrictions, the solutions are within reach. Learn more in our latest position paper 👉 https://bit.ly/41NAcfW

The final week of #DigestiveHealthMonth is here! This month has built the evidence – and the message is clear: urgent change is needed to reduce the burden of digestive diseases & cancers. Now, we’re calling for policy action across Europe 👉 https://bit.ly/4iN57Ps #EUNewsline