New paper from my lab! We investigated how clonal evolution, plasticity and the microenvironment shape intra-lesion heterogeneity in metastatic prostate cancer. Our findings reveal how convergent evolution in cancer might be more common than expected. www.nature.com/articles/s41...
Recurrent intra-tumour heterogeneity is a hallmark of metastatic prostate cancer - Nature Communications
The evolutionary elements contributing to end-stage prostate cancer are still unclear. Here, single-cell multi-omics and whole-genome sequencing of 34 metastatic lesions obtained from 9 patients by ra...
nature.com
