Cells change how they make energy over days, not minutes. A single time point can miss when a shift starts and whether cells recover. Resipher captures live-cell respiration continuously inside the incubator, over days to weeks. lucidsci.com
Lucid Scientific
@lucidscientific.bsky.social
The world's first real-time cell culture monitor to measure oxygen consumption in standard multi-well plates, providing continuous insight from your incubator.
The FDA recently swapped "animal" for "nonclinical" in its safety testing rules. Human models take weeks to build. Resipher measures their respiration the whole time, right in your incubator. Published in iPSC models, organoids and spheroids: lucidsci.com/resources#pu... #NAMs
Can one 96-well plate follow algae making oxygen by day and using it by night? Jolly, Place and team at IMET used Resipher to track dinoflagellate photosynthesis and respiration in 32 wells at once, with rates in line with carbon fixation. Paper below.
How do cells rewire fat metabolism when oxygen runs low? At #HypoxEU, @LozaValdes (@UniHeidelberg) showed losing the E3 ligase RNF145 helps cells survive hypoxia by storing fatty acids as triacylglycerol instead of toxic lipids. Great poster, Angel! #Hypoxia #LipidMetabolism
At HypoxEU Live, Eva Ferro (@cnc-uc.bsky.social) showed how oxygen priming reshapes the proteome of umbilical cord MSCs from 9 donors. Resipher tracked their respiration at 24, 48 and 72 h.
Do struggling neurons get help from their neighbors? Riou, Grimm et al. at @biomedizin.unibas.ch show astrocytes transfer mitochondria to P301L tau neuronal cells. Resipher tracked respiration from plating: +91% after transfer. lucidsci.com/resources?publication=QN1pawUcr1Pc2czbZuzJ6 #Tau
2026 is poised to be an exiting year of continued breakthroughs and discoveries in the life sciences industry. This Biocompare article features insights from insiders as to what we might expect in cell & gene therapy, biologics, antibodies, and other fields. www.biocompare.com/Editorial-Ar...
A Look Ahead: Predictions for the Life Sciences in 2026
Industry insiders share what’s on their radar for next year.
biocompare.com
Wishing you and yours a joyful holiday season and a spectacular New Year!✨ As we look back on this year, we're filled with gratitude for the team, customers, and community who make our work so rewarding. May your days be filled with warmth, laughter, and everything that makes the holidays special.🎄
Human heart–macrophage assembloids were generated that produced tissue-resident macrophages which influence cardiac organization and electrical behavior. Bioenergetic function was assessed by measuring OCR using Resipher, enabling comparison of mitochondrial respiration. cell.com/cell-stem-ce...
Excellent example of Resipher's use in cancer metabolism and therapeutic discovery. Using Resipher, the study showed that Zelenirstat significantly reduces oxygen consumption in colon and prostate cancer cells, validating its impact on mitochondrial respiration. aacrjournals.org/mct/article/...
It's time to step up your bioenergetic profiling research! With Resipher, you'll enjoy stress-free bioenergetic profiling of mitochondrial ETC function and FAO substrate metabolism, including long-term baselines for stable respiration. Bbook a demo and see for yourself >>> lucidsci.com/resipher
Resipher in Action! This study examined how loss of HMGCR, the rate-limiting enzyme in cholesterol synthesis, affects muscle development. Using Resipher, the authors measured oxygen consumption in myotubes derived from HMGCR-deficient myoblasts. febs.onlinelibrary.wiley.com/doi/full/10....
Lucid EMEA Sales Director Mike Lu wraps up his 2025 conference schedule this week in Saudi Arabia! Come say hi and learn more about our #Resipher technology if you're planning to attend We will have a poster at this event. Event info here >>> natureconferences.streamgo.live/brain-health...
We have so much to be grateful for 🍁 happy Thanksgiving to all!
Excellent presentation today by our VP of Sales Ryan Titmas at today's SfRBM Conference session! Great to see such an engaged audience for this event! #sfrbm #sfrbm2025
👀👀 Take a peek at the manufacturing behind Resipher's single-use sensing lids! Our nanoplotter first captures an image of a sample droplet on the white slide, then deposits red sensing material on each of the 1mm diameter probe tips with micron-level precision. Learn more >>> lucidsci.com/resipher
Starting Thursday, this year's MetNet International Meeting will focus on "Emerging Trends in Translational Metabolic Research". Lucid's Mike Lu will be delivering a talk entitled, "Resipher for Real-Time, Long-Term Metabolic Analysis." Event info here >>> scb.iec.cat/11th-annual-...
Lucid VP of Sales Ryan Titmas and VP of Product Strategy Silke Grainger are heading to DC next week to represent us at the SfRBM 2025 Conference! We're excited to serve as a Groundbreaking Discovery Sponsor for this great event. Come say hi if you're planning to attend 👋 sfrbm.org/meetings/sfr...
Ailing mitochondria got you down? Mitochondrial impairment is a universal cause and/or consequence of cellular dysfunction, impairment, and death. With Resipher, you can measure and track mitochondrial respiration in any standard cell culture model system. Learn more >>> lucidsci.com/resipher
Dig deeper into mitochondrial function with Resipher! In this "Resipher in Action" spotlight piece, Pardo et al. investigated how exposure to a complex biomass burning pollution mixture affects liver cell metabolism in diet-induced NAFLD. Read more here >>> www.sciencedirect.com/science/arti...
In less than two weeks we'll be putting our fall jackets aside and heading to sunny San Diego for Neuroscience 2025! Lucid's Ghainaa Abousleiman and Kin Lo will be heading up our exhibit, so make sure to stop by if you're planning to attend. Event info >>> www.sfn.org/meetings/neu...
Resipher in Action! Check out this example of how it deepens research within cancer metabolism and therapeutic discovery. Resipher was critical for capturing the sharp reduction in mitochondrial respiration that accompanied the metabolic stress. Publication >>> aacrjournals.org/cancerres/ar...
Could gray hair be your unsung superpower against cancer? A recent study suggests that we've evolved to dispose of potentially tumorous cells in exchange for a little salt & pepper. www.sciencealert.com/gray-hair-mi...
Gray Hair Might Be The Body's Way of Avoiding a Deadly Cancer
Gray hair is nothing to be ashamed of.
sciencealert.com
Mitochondrial fitness testing — powered by Resipher! With Resipher, investigators can continuously monitor mitochondrial function and metabolic shifts in real-time and over long term using their own cell model setup. Will your mitochondria rise to the challenge? Find out today >>> lucidsci.com
We're honored to sponsor this year's Targeting Mitochondria Conference, hosted by the World Mitochondria Society in Berlin. VP of Sales Ryan Titmas and EMEA Sales Director Mike Lu will be there representing Lucid as exhibitors - stop by our booth if you're attending! Event info >>> wms-site.com
In this past study, Nikitina et al. demonstrate that real-time oxygen consumption rate measurements collected with Resipher during the first 72 hours of iPSC differentiation can accurately forecast final cardiomyocyte yield & identify successful outcomes. Link >>> pubmed.ncbi.nlm.nih.gov/37431876/
Lucid Scientific CEO Walker Inman provides an overview of how our Resipher device can work with your 96-well plate to provide valuable insights into cellular metabolism. Learn more >>> lucidsci.com ✔
In this past study, an under-oil culture system was developed that stabilizes the microenvironment by reducing evaporation. Resipher was used to monitor oxygen consumption in hNPCs, confirming the creation of a low-oxygen, in vivo-like environment. View it here >>> sciencedirect.com/science/arti...
Our march through Europe continues with next week's European Association for Cancer Research Neuroscience Conference, held in Spain. Lucid's Mike Lu will be representing our booth, exhibiting our #Resipher device and other technologies. Stop by and say hi! Event info >>> eacr.org/conference/c...
The study investigates the mechanism by which the ceramide analog LCL768 induces mitophagy and metabolic stress in HNSCC. Resipher was used to measure real-time OCR over 24 hours to assess the impact of mitophagy on mitochondrial respiration. View it here >>> aacrjournals.org/cancerres/ar...