Yay! Just saw that we got the cover of the August 1 MBoC! Woot! 🎉 Please check out our paper if you are interested in it the tubulin code or early development. www.molbiolcell.org/doi/10.1091/...
Hypothesis Fund
@hypothesisfund.bsky.social
Nimble funding for nimble minds. www.hypothesisfund.org
How can we study life’s deep evolutionary past? By bringing it into the lab! This @asm.org feature highlights our on-going efforts. Read how synthetic biology allows us to reconstruct ancient microbial systems, test hypotheses about early metabolism and explore how life and Earth co-evolved. 🌍
Synthetic biology is advancing how scientists study early microbial life. Their findings could revolutionize how we think about Earth’s earliest residents—and those that exist today. asm.org/articles/202...
✨ Meet our newest awardees, who are wading into the unknown to uncover new knowledge about the origin of complex life, antimicrobial peptides, social behavior, regeneration, and cell development. Learn about their projects: bit.ly/HFAwardees and hear from their #HFScouts in our 🧵 /1
For the last 5 years, my lab has focused on developing mutational scanning methods and learning how to answer specific questions in protein biology. @matthewkhoward.bsky.social and I wrote a review on experimental decisions and future directions for our nascent field! doi.org/10.1146/annu...
Mechanistic Mutational Scanning to Uncover the Secret Life of Proteins
Deep mutational scanning (DMS) has emerged as a transformative tool for dissecting individual protein function and broader cell biology. DMS methods enable comprehensive interrogation of sequence–func...
annualreviews.org
The symbiotic relationship between Ned Ruby's lab, who focus primarily on the bacteria, Vibrio fischeri and Margaret McFall-Ngai's lab, who focus primarily on the bobtail squid, has led to a deep understanding of what symbiosis really means at the molecular level youtu.be/M5rZ52wcQ08
You Gotta Be Squid-ding Me!: microTalk with Ned Ruby and Margaret McFall-Ngai at ASM Microbe 2026
YouTube video by ASM - Microbes Make Our World
youtu.be
🚨VIROMICS WORKSHOP 2026🚨 Application is now OPEN for the 8th International Viromics Workshop, Oct. 14-16, 2026, in-person at Ohio State University. Application closes Aug. 7. Apply: forms.gle/pJFLDCNEBvAe... Full details: u.osu.edu/viruslab/vir... #viromics #viruses #ecology #workshop
forms.gle
Folks quick to dump on the fact that latest group of amazing @hypothesisfund.bsky.social awardees are all men (n=5) are encouraged to check out the list of all recent awardees to celebrate all their achievements: www.hypothesisfund.org/portfolio
Portfolio — Hypothesis Fund
The Hypothesis Fund enables scientists to take intelligent risks. To defy the predominant expectations in their field. To go after their big ideas.
hypothesisfund.org
🔬 Announcing our newest awardees! 🌟 These brilliant minds are pushing boundaries across microbiology, immunology, infectious disease, earth systems, and neuroscience. Celebrate with us as we highlight their projects today👇 in our 🧵: 1/ bit.ly/HFAwardees
🙋🏾♀️I am honored to have been supported by @hypothesisfund.bsky.social and can attest that they intentionally select their awardees. There is incredible representation at the scout level as well. Have nothing but good things to say about HF leadership - there is always improvement but the bar is high!
Folks quick to dump on the fact that latest group of amazing @hypothesisfund.bsky.social awardees are all men (n=5) are encouraged to check out the list of all recent awardees to celebrate all their achievements: www.hypothesisfund.org/portfolio
Incredibly proud of Messi Haile @mehsehret.bsky.social, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in @cellpress.bsky.social! tinyurl.com/4p3md2eb 🦠❄️🔬
🔬 Announcing our newest awardees! 🌟 These brilliant minds are pushing boundaries across microbiology, immunology, infectious disease, earth systems, and neuroscience. Celebrate with us as we highlight their projects today👇 in our 🧵: 1/ bit.ly/HFAwardees
1/ Mitochondrial Na⁺ links metabolism, Ca2+ signaling and disease. We know how it gets in, how it gets out, and proteins that use it. But: we've never actually seen Na⁺ in single mitochondria in live cells. We started with an unusual observation, went down a rabbit hole & found some cool biology .
Katalin Karikó's inspiring story captures the power of persisting against all odds -- a timely reminder for us in science. We're proud to have produced this winning episode, in partnership w/ @scifri.bsky.social. Stories like hers are at the ❤️ of why we support early-stage, unconventional science.
We’re honored to have won a First Place award from the Public Media Journalists Association for "The Leap: I Was Considered A Nobody." www.pmja.org/pmja-2026-aw... "The Leap" is a production of the Hypothesis Fund @hypothesisfund.bsky.social, in partnership with Science Friday.
Great to see HF Awardee Tim Cernak chat with our friends at @scifri.bsky.social!
In our #PictureOfTheWeek, a sea turtle named Bellatrix is riddled with tumors. Usually surgery is the only option for turtles, but chemist Tim Cernak hopes to change that. Photo Credit: Jen Zuberer
Always bring us joy to see our HF folks together!
Day 1 of @asm.org #ASMmicrobe2026 was great! Wonderful reconnecting with the Microbiology community, including fellow @hypothesisfund.bsky.social family members @laahrs.bsky.social & @paulturnerlab.bsky.social!
Don't miss @hypothesisfund.bsky.social awardee Tim Cernak on @scifri.bsky.social! Incredible mission-driven science that we are proud to support! He is also currently hiring a postdoc: careers.umich.edu/job_detail/2... www.sciencefriday.com/segments/wil...
Meet the drug developer taking on wildlife diseases
Chemist Tim Cernak has a wild to-do list: Cure sea turtle cancer. Save frogs from fungal diseases. Take on avian flu.
sciencefriday.com
A novel angle on antibiotic resistance may come from understanding how bacteria protect themselves from viruses. Dr. Karasov’s bold new project explores how bacterial antiviral defense systems could reveal entirely new insights into antibiotic resistance and fundamental biology.
We are recruiting participants for endometriosis research. Our lab is studying menstrual blood to develop better diagnostic and therapeutic tools for endometriosis. If you would like to participate, please complete this survey: redcap.berkeley.edu/surveys/?s=8... #Endometriosis #WomenHealth
The @hypothesisfund.bsky.social has awarded a prestigious seed grant to @uofubiology.bsky.social professor Talia Karasov, who researches the microbial weapons bacteria inflict on each other in an evolutionary arms race that might hold the keys to addressing the threat of antibiotic resistance.
U biologist wins seed grant to deepen research into tailocins, the weapons microbes use on each other - @theU
Hypothesis Fund supports early-stage innovative research that aims to improve the health of people and the planet.
attheu.utah.edu
Univ. Utah biologist (the amazing Talia Karasov) wins seed grant to deepen research into tailocins, the weapons microbes use on each other. attheu.utah.edu/facultystaff... @hypothesisfund.bsky.social @utah.edu
U biologist wins seed grant to deepen research into tailocins, the weapons microbes use on each other - @theU
Hypothesis Fund supports early-stage innovative research that aims to improve the health of people and the planet.
attheu.utah.edu
Please check out my interview on the Out of Patients Podcast with @oliverbogler.bsky.social. We chatted about the hidden curriculum and my experience starting @ucdavis.bsky.social, feeling like a failure, and being supported by the Life Science Editors Foundation. podcasts.apple.com/us/podcast/s...
Standard Deviation S2 E3: The Hidden Curriculum
Podcast Episode · Out of Patients with Matthew Zachary · May 14 · Bonus · 12m
podcasts.apple.com
Very excited to share the most recent review from our lab, available online and soon in #BiochemSocTrans! This review covers an area of ongoing research in the lab: the role of TAM receptors in the spread of non-enveloped viruses portlandpress.com/biochemsoctr...
TAM receptor tyrosine kinases as potential mediators of the non-lytic spread of non-enveloped viruses
Abstract. Tyro3, Axl, and Mer are receptor tyrosine kinases that comprise the TAM receptor family. These receptors, originally identified as orphan receptors, do not bind growth factors but rather lig...
portlandpress.com
The Bisson Lab at IU (bissonlab.com) is hiring makers/builders/engineers across all career stages to join our team in one of the most exciting and crazy projects I've set to work on. Candidates can email us: saltylab@iu.edu More info in the thread [1/3]
I’m honored to join the Scouts of the Hypothesis Fund @hypothesisfund.bsky.social and help bring beautiful, hard-to-categorize, and easy-to-underestimate biological questions to the fore. Excited for this!
🤩 We’re thrilled to announce 4 new Hypothesis Fund Scouts - congratulations and welcome to Orit Peleg, Kay Bidle, Denise Okafor, and Cigall Kadoch! Follow along today to learn more about each new Scout and join us in celebrating them! 1/
Meet new #HFScout Cigall Kadoch, whose pioneering research has fundamentally changed how we understand chromatin remodeling – the regulatory machinery that controls which genes🧬 get turned on and off. 1/
Say hello to #HFScout Denise Okafor (@cdokafor.bsky.social), who combines powerful computer simulations + experimental approaches to study protein-ligand interactions–which has wide-ranging implications for metabolic diseases, reproductive conditions, & infectious diseases. 1/
Welcome #HFScout Kay Bidle, a molecular microbial oceanographer whose pioneering research on marine phytoplankton-virus interactions, ocean physics ⛈️, and ecosystem dynamics 🪼 is transforming our understanding of the Earth’s carbon cycle. 🌎 1/
👋 Meet #HFScout Orit Peleg (@oritpeleg.bsky.social), trained as a physicist + computer scientist whose research combines theory, computation, experiments, & field biology to study how groups of organisms sense, decide, & build together, e.g. the fascinating collective behavior of honeybees🐝. 1/
🤩 We’re thrilled to announce 4 new Hypothesis Fund Scouts - congratulations and welcome to Orit Peleg, Kay Bidle, Denise Okafor, and Cigall Kadoch! Follow along today to learn more about each new Scout and join us in celebrating them! 1/
New paper out today with Karinne Tennenbaum, @karlycohen.bsky.social, and Chas Bissell! We show that Cyclothone (most abundant fish in the sea) have unique teeth & they appear in the Earliest Eocene >40 million years earlier than their oldest body fossils. royalsocietypublishing.org/rspb/article...
The gentle reminder I needed to continue to show up authentically in science! Grateful and overjoyed.
📣 Bold science alert! We're thrilled to announce our latest awardees who are pushing the boundaries of research in aging, regeneration, and bacterial resilience. bit.ly/HFAwardees Hear from the #HFScouts who championed these talented scientists👇 in our 🧵: 1/