🚑 In 4,854 neurological visits, seizures and headaches comprised 64% of chief complaints. Neurological patients had a nearly fivefold increased risk of requiring immediate lifesaving interventions compared to non-neurological patients. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Check out the September issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

🦴 In 30 patients with unexplained facial pain, internal jugular vein entrapment caused superior petrosal sinus dilation and spinal trigeminal nucleus venous congestion. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

🌍 The EAN Environmental Influences in Neurology Task Force outlines core concepts and 10 strategic priorities adapted from the WHO framework to build climate-resilient neurology and safeguard brain health. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #BrainHealth #ClimateChange

🧠 Is PLS purely a motor disorder? A population-based registry study reveals cognitive and/or behavioral impairment in nearly 30% of 32 PLS patients at diagnosis, predominantly affecting executive function and social cognition. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #PLS

🏥 The FERES initiative demonstrates that large-scale, multinational stroke research and benchmarking can be conducted in Europe using a privacy-preserving federated approach. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #Stroke

🛡️ Does adult thymectomy increase long-term cancer or mortality risk? In a 10-year propensity-matched cohort study, thymectomy was not associated with excess mortality or extrathymic malignancy compared to cardiothoracic surgery controls 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

🔬 A Belgian multidisciplinary consensus establishes a stepwise diagnostic pathway integrating blood-based biomarkers, CSF, and amyloid-PET to ensure accurate, timely, and equitable early-stage diagnosis. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #AlzheimersDisease #Dementia

⚡ Evaluating diagnostic rigor in CIDP: In 339 patients and 339 controls, the revised 2021 EAN/PNS criteria demonstrated higher specificity (86% vs 78%) for definite/probable CIDP compared to the 2010 EFNS/PNS guidelines. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

🩸 Arterial pathology in Neuro-Behçet's syndrome may be more common than recognized. Vessel wall imaging revealed arterial involvement in 41% of patients, predominantly in the posterior circulation with a concentric thickening pattern. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

💊 In the prospective INLEVO-LIFE PD study, inhaled levodopa (CVT-301) enhanced health-related quality of life (PDQ-39) and reduced daily OFF time by 1.6 hours. Adverse events related to CVT-301 were reported in 35% of the patients. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

🤖 The new EAN Task Force on AI launches a multidisciplinary initiative featuring a modular European educational curriculum, survey-driven gap analysis, and tailored ethical-regulatory guidelines. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #ArtificialIntelligence #DigitalHealth

Check out the August issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

🧠 In a target trial emulation direct MT was not non-inferior to IVT + MT treatment beyond 4.5 h from symptom onset or at wake-up, with IVT before MT yielding higher successful recanalization rates. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #Stroke #Thrombectomy #Neurology

🗣️ Intensive speech-language therapy significantly improves post-stroke dysphagia. While adjunctive tDCS did not show an overall additional benefit, exploratory findings suggest it may help patients with infratentorial strokes. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

💊 In a cohort of advanced Parkinson's disease, neuropsychiatric adverse events from foslevodopa/foscarbidopa were mild-to-moderate. Except for impulse control disorders, baseline cognitive impairment or prior hallucinations did not increase the risk of new psychotic events.

🧩 A new systematic review highlights that targeted neuropsychological tests focusing on visuoperceptual and attentional domains can successfully differentiate prodromal DLB from Alzheimer's disease and healthy aging. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #LewyBodyDementia

🔬 Novel diffusion MRI shows that the neurite density index (NDI) of corticospinal subfibers, especially combined with serum NfL, effectively identifies upper motor neuron degeneration in prediagnostic ALS. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #ALS #Neuroimaging

🩸 Exploring blood biomarkers for genetic FTD: A multiplex CNS panel reveals distinct plasma proteomic signatures, identifying unique alterations like elevated GFAP and VCAM1 in GRN-FTD, and reduced NPTXR in C9orf72-FTD. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

📉 Do systemic inflammatory markers predict the efficacy of anti-CGRP therapies? A large real-world study shows that baseline serum hs-CRP and TNF-α levels do not predict treatment response to erenumab in migraine prevention. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #Migraine

🌐 Open science is key to tackling neurodegenerative diseases. This review outlines the current barriers to sharing brain imaging data and advocates for unified legal frameworks and a new academic credit system to reward data stewardship 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

💊 In an open-label trial of cenobamate, patients taking fewer concomitant antiseizure medications experienced significantly fewer, milder, and faster-resolving adverse events, underscoring the benefits of treatment simplification. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Check out the July issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

🔄 Switching to ocrelizumab provides durable, long-term disease control in early relapsing multiple sclerosis with suboptimal response to previous therapies. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #MultipleSclerosis #MS

🧬 Vutrisiran and patisiran demonstrate superior efficacy over older pharmacological interventions in improving neuropathy impairment and QoL in ATTRv-PN, although these findings should be regarded as hypothesis-generating 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #Amyloidosis

🧪 Electrochemical skin conductance (ESC) serves as a sensitive, noninvasive biomarker for disease progression and survival in multiple system atrophy (MSA). 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #MultipleSystemAtrophy #MovementDisorders #Biomarkers #Autonomic #Neurology

⚡ Noninvasive neuromodulation shows promising efficacy for migraine and cluster headache management. However, a systematic review reveals substantial variability in study designs and inconsistent adherence to guidelines. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

🚶 Lesion network mapping reveals that post-stroke falls are driven by disruptions in cortical networks supporting voluntary motor control and whole-body coordination, rather than subcortical gait-modulating structures. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #Stroke

🏥 Mechanical thrombectomy in acute ischemic stroke due to cervical artery dissection achieves high recanalization rates and favorable 90-day outcomes, comparable to non-dissection strokes despite more tandem occlusions. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

⚖️ Both erenumab and onabotulinumtoxinA produce significant, comparable reductions in headache and migraine frequency after 6 months in chronic migraine. Erenumab demonstrated greater improvements in MIDAS, anxiety, and depression scores 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro