Lingyin Li, PhD
@lingyinli.bsky.social
Prof. at @stanford.edu & Core Investigator at @arcinstitute.org | Uncovering drug targets in innate immunity and developing therapeutics for cancer and autoimmunity | Mother of 2 | https://arcinstitute.org/labs/lilab
Stanford MSTP student Songnan Wang and I wrote a preview on Nan Yan's discovery of the immunotransmitter function of 2-5A in the dsRNA sensing. With two big fields emerging, we draw conceptual comparisons with the immunotransmitter cGAMP in the dsDNA sensing. authors.elsevier.com/a/1kuse3qNrU...
authors.elsevier.com
At the AACR IO meeting in LA. Come say hi if you are here.
Exciting new discovery from colleagues @stanfordmedicine.bsky.social, astrocyte metabolism compromised by amyloid and tau oligomers leading to insufficient support for neurons. Possible new target for treating AD. www.science.org/doi/10.1126/...
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Impaired cerebral glucose metabolism is a pathologic feature of Alzheimer’s disease (AD), with recent proteomic studies highlighting disrupted glial metabolism in AD. We report that inhibition of indo...
science.org
What a great piece of news so many years in the making. Congratulations Profs Monjie and Mackall.
Carolyn Bertozzi@carolynbertozzi.bskyverified.social · 2y agoCongratulations Profs Monjie and Mackall and collaborators at Stanford Med, GD2 CAR-T shows efficacy in phase 1 brain cancer trial @stanfordpress.bsky.social www.nature.com/articles/s41...