Jorge Peña Peña

@jpenap.bsky.social

❤️ PhD student @CNIC interested in heart regeneration and cardiomyocyte biology.

Very proud of this collaboration with Elly Tanaka and Elad Bassat. Jorge Peña @jpenap.bsky.social from our lab skillfully conducted our contributions. @regen-hearts.bsky.social #HeartRegeneration

Elad Bassat@regen-hearts.bsky.social · 8mo ago

1/ Can #Axolotls teach us new things about #HeartRegeneration? A great collaboration between Elly Tanaka and Miguel Torres labs. We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that? doi.org/10.64898/202...

8/ But what about mammals? Activating AXL in mouse cardiomyocytes protected them from cell death and induced dedifferentiation, including structural and metabolic changes similar to those seen in regenerating species.

Over expression of AXL in mouse cardiomyocytes promotes sarcomere disassembly