Successful trial ✅️ An international team coordinated by #MedUniVienna demonstrated in a #clinicaltrial that #TorqueTenovirus-guided dosing of #immunosuppressants in #kidneytransplant recipients is safe. More about the @ttvguidetx.bsky.social​ study coordinated by @gregorbond.bsky.social​! ⬇️

Biomarker-guided immunosuppression following kidney transplantation successfully tested

Further details!

meduniwien.ac.at

📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Systematic Review of Efficacy and Safety of Avacopan in Real-World Clinical Practice https://www.kireports.org/article/S2468-0249(25)00771-5/fulltext

Proposed algorithm for the application of rituximab in minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS) ca. 2020 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/32942039/

'Rare Kidney Diseases' is a peer-reviewed, #OpenAccess journal dedicated to advancing clinical and translational knowledge in glomerular, autoimmune, and genetic kidney diseases across all age groups. bit.ly/3ZG9FA5 @glomcon.org #NephSky @kronbichlerlab.bsky.social

An 80-year-old man presented with a 4-day history of a rash on his abdomen. Physical examination was notable for periumbilical erythema and a small gray protrusion in the umbilicus. Read the full case details: nej.md/4pYF5NO @i-med.ac.at #MedSky #DermSky

SGLT-2 Inhibition in ADPKD? DAPA-PKD & STOP-PKD - Prof. Emilie Cornec Le Gall & Prof. Roman-Ulrich Müller youtu.be/9e-UFBnIyDI?... @ecorneclegall.bsky.social @muellerrom.bsky.social @kronbichlerlab.bsky.social @sarahelena.bsky.social @gunnarheine.bsky.social @marcussaemann.bsky.social

SGLT-2 I in ADPKD? DAPA-PKD & STOP-PKD - Prof. Emilie Cornec Le Gall & Prof. Roman-Ulrich Müller

YouTube video by MARKUS at HOMe

youtu.be

Extrarenal “crescent” in multisystem granulomatosis with polyangiitis doi.org/10.1016/j.kint.2025.03.028 🔹Paravertebral masses in systemic vasculitides such as GPA are rare 🔹This pt had a rupture of the A. colica dextra leading to GI bleeding #MedSky #NephSky @i-med.ac.at @kronbichlerlab.bsky.social

The International Vasculitis Workshop is coming up! One of my favorite meetings for it's sense of community, and possibilities of forming meaningful collaborations (PEXIVAS was hatched in one of them). Call for early career scientists is here mailchi.mp/icmsaust/ivw...

As the quantity of RCTs in nephrology goes up, how is the quality shaping up? CONSORT Reporting standards, ANCA vasculitis edition from @abruch.bsky.social @kronbichlerlab.bsky.social et al in @kireports.bsky.social www.kireports.org/article/S246...

It was a pleasure to collaborate with @kronbichlerlab.bsky.social and Dr. Astrid Weins on this article. We describe transformations in our understanding of podocytopathies, and novel treatment approaches in light of those advancements. journals.lww.com/co-nephrolhy...

New insights into the biology and treatment of minimal... : Current Opinion in Nephrology and Hypertension

sease and focal segmental glomerulosclerosis, there has been a transformation of our understanding of disease pathogenesis and treatment rationale. Recent findings Antinephrin antibodies are common...

journals.lww.com

Secondary #TMA represent a major unmet medical need. Grateful for the opportunity to review the role of #complement and discuss when to consider complement inhibitors in these dramatic diseases. 🙏 to outstanding co-authors and the #ERA IWG @kronbichlerlab.bsky.social @ndt-era.bsky.social

NDT@ndt-era.bsky.social · last yr.

Complement activation in secondary thrombotic microangiopathies doi.org/10.1093/ndt/... 👉This review summarizes the current understanding and future directions in the management of secondary TMA, emphasizing the potential of complement inhibition as therapeutic strategy

Understanding the role of anticoagulation in nephrotic syndrome: Please complete this survey - qualtricsxm564785h8t.qualtrics.com/jfe/form/SV_... It takes 5 minutes and is highly appreciated. 10 more responses are needed

Congratulations @johannmorelle.bsky.social and team!

Johann Morelle@johannmorelle.bsky.social · last yr.

1/ Thrilled to share our latest work ‘Mass Spectrometry with Data-Independent Acquisition for the Identification of Target Antigens in Membranous Nephropathy’, just published in @ajkd.bsky.social www.ajkd.org/article/S027... #CHUUCLNamur #deDuveInstitute @inserm.fr #UCLouvain #CuSL A thread

Disease-modifying anti-nephropathic drugs (DMANDs) – a definition proposed by the Immunonephrology Working Group (IWG) of the European Renal Association (ERA) doi.org/10.1093/ndt/...

👏👏👏 @kronbichlerlab.bsky.social #FSGS #Nephroticsyndrome #APOL1 just one small note on %FPE/genetics. The concept that genetic forms have ⬇️FPE is confounded. Most FSGS related to slit-diaphragm genes presenting with NS have ⬆️FPE. We see nearly total FPE with TRPC6, INF2, NPHS1, NPHS2, MYO1E et al

NDT@ndt-era.bsky.social · 2y ago

Management of adult patients with podocytopathies: an update from the ERA Immunonephrology Working Group 🆓 doi.org/10.1093/ndt/...

A true group effort and work of 2 years! Hope you are enjoying it!

Kidney International@kidneyint.bsky.social · 2y ago

The effects of #plasmaexchange and #glucocorticoids on early kidney function among patients with #ANCA-associated #vasculitis in the PEXIVAS trial doi.org/10.1016/j.kint.2024.11.029 #OpenAccess #glomerulonephritis #ESKD #NephSky #MedSky

Phenotypic differences between AAV patients in Japan (compared to USA/EU) are obvious. In this study, we surveyed patients presenting during the early phase of the pandemic. A striking difference in the use of glucocorticoids at 6 months has also been observed! academic.oup.com/rheumatology...

Sex dimorphism in #kidney health and disease: mechanistic insights and clinical implication doi.org/10.1016/j.kint.2024.08.038 #OpenAccess #KIReview #AKI #acutekidneyinjury #CKD #kidney #autoimmunedisease #NephSky #SkyNeph #MedSky

In a sub-analysis of the PEXIVAS trial, we analysed eGFR course over the first 52 weeks (www.kidney-international.org/article/S008.... Key: while the initial increase in eGFR is significant (PLEX vs no-PLEX), no major difference is seen at 52 weeks

A call for potential candidates. The YNP of the European Renal Association has launched the list of 2025 mentors for the mentorship program! www.era-online.org/research-edu... I am delighted to work with one mentee for the first time and looking forward to your submission!

Last lab meeting of the year. Those joining virtually were very unlucky today 😍! Thanks to my wonderful Team for a successful year!

In this Review on ANCA-associated glomerulonephritis, we provide a comprehensive overview of ANCA-associated glomerulonephritis, spanning from diagnosis, prognosis to treatment (induction and remission), and dedicate a section on transplantation #karger #GlomDis karger.com/gdz/article/...

ANCA-associated glomerulonephritis – diagnosis and therapy Proceedings of the Henry Shavelle Lectureship

Abstract. Background. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) frequently affects the kidney. Glomerulonephritis (GN) in AAV, ANCA-GN, not only dictates therapeutic deci...

karger.com

Weekend update! NephSky up to pack 5! 5th pack go.bsky.app/JJ4h8su 4th pack: go.bsky.app/YeuH82 3rd pack: go.bsky.app/2yLiYN4 2nd pack go.bsky.app/N27Kzri 1st pack: go.bsky.app/H4td28C + PedNeph pack from @kidneywiki.bsky.social and many more Reply or DM with what I have missed

If you spend more time eating these delicious matcha-coconut balls rather than discussing research at our LabMeeting; you know that you have excellent PhD students! @ilayberke.bsky.social

Highly recommended to join this meeting in Frankfurt!

Gunnar Heine@gunnarheine.bsky.social · 2y ago

17.01.2025 Frankfurt Wir laden herzlich zu "MARKUS at HOMe Unplugged 2025" ein! Fortbildungspunkte sind bei der Hessischen ÄK beantragt; die Teilnahme ist gebührenfrei. Vorherige Anmeldung ist erbeten (marion.schirmeister@agaplesion.de) www.youtube.com/watch?v=s3tr... @marcussaemann.bsky.social

A true pleasure to see this paper published in Kidney Int Rep now! We have examined glomerular lesions in ANCA GN and found that a fully trained machine learning approach is capable to assess most ANCA-GN lesions accurately. www.kireports.org/article/S246...

My first post here is devoted to a paper I really love; from the Chapel Hill group a really thought-provoking article on the three clinical phenotypes of AAV (www.kidney-international.org/article/S008... published in KI! Lung lesions seem to be non-complement-dependent in mice!