Thankful that I could share my work on AI, New Amino Acids, and the Future of Bioproduction today at the Wyss Retreat. I look forward to continuing to collaborate with this multidisciplinary, creative community. Together, we can create a more sustainable future with enhanced enzymes! #WyssRetreat25

A protein language model trained to predict subcellular localization for human proteins can generate de novo sequences with the desired localization and identify pathological mutations. @itamarchinn.bsky.social @pgmikhael.bsky.social www.science.org/doi/10.1126/...

🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/... Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social

Protein codes promote selective subcellular compartmentalization

Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...

science.org

The preprint is now on bioRxiv www.biorxiv.org/content/10.1... and the model on HuggingFace 🤗 huggingface.co/boltz-commun... !

Gabriele Corso@gcorso.bsky.social · 2y ago

Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!

Two BioML starter packs now: Pack 1: go.bsky.app/2VWBcCd Pack 2: go.bsky.app/Bw84Hmc DM if you want to be included (or nominate people who should be!)

Kevin K. Yang 楊凱筌@kevinkaichuang.bsky.social · 2y ago

I tried to make a bioml starter pack. DM if you want me to add or remove you? go.bsky.app/2VWBcCd