Catheter-Directed Recombinant Tissue Plasminogen Activator for Treatment of Aortic Root and Coronary Artery Thrombosis in Single Ventricle Patients: A Case Series

We present a case series of 4 single ventricle patients with either native aortic root and/or coronary thrombosis who underwent catheter-directed thrombolysis with recombinant tissue plasminogen activ...

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Uncovering the Unexpected—True Lumen Compression by Subintimal Stent Causing Recurrent Acute Limb Ischemia for 15 Years: A Case Report

The mechanism of stent failure in acute limb ischemia includes a broad spectrum of thrombotic and mechanical factors. We present a patient with recurring Rutherford Class 2A acute limb ischemia, who u...

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Valve-in-Valve Transcatheter Aortic Valve Replacement Using the TRITON Technique: A Case Report

Coronary artery obstruction is a rare but life-threatening complication of valve-in-valve transcatheter aortic valve replacement, particularly in patients with externally mounted leaflet bioprostheses...

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SCAI/ASE/HRS/SIR/SVS Expert Consensus Statement on Enhanced Radiation Protection: Time for Mandatory and Urgent Action

Health care professionals in fluoroscopic laboratories face significant occupational hazards, including cancer, cataracts, and reproductive concerns due to prolonged exposure to iodizing radiation, an...

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LithiX Hertz Contact Lithotripsy Catheter for Calcium Modification: Insights From OCT and μFR Evaluation in Three Didactic Cases

The LithiX Hertz Contact Intravascular Lithotripsy System (Elixir Medical) is a new calcium fragmentation device that uses metal hemispheres on a semicompliant balloon to impart high contact stresses ...

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Artificial Intelligence-Derived Fractional Flow Reserve in Routine Clinical Practice: An International Multicenter Retrospective Study

Artificial intelligence-based fractional flow reserve (AI-FFR) incorporates a machine learning-based algorithm to derive FFR directly from angiography. Its accuracy compared with invasive FFR has not ...

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Transcatheter Aortic Valve Replacement in Patients with Symptomatic, Severe Aortic Regurgitation: 1-Year Outcomes of the J-Valve Transfemoral Early Feasibility Study

Clinically significant native aortic regurgitation (AR) increases with age. Surgical aortic valve replacement has been the only curative guideline-recommended therapy, while transcatheter options rema...

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Mechanical Thrombectomy of an Obstructive Mechanical Mitral Valve Thrombus Using the FlowTriever Device With Embolic Protection: A Case Report

Management of obstructive mechanical mitral valve thrombosis in patients with prohibitive surgical risk and contraindication to thrombolytics is not well defined. Transcatheter approaches, such as man...

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Clinical Characteristics and Outcomes of Cardiogenic Shock in Acute Myocarditis Versus Takotsubo Cardiomyopathy: A Propensity Matched Nationwide Analysis

Cardiogenic shock (CS) is a life-threatening complication of acute myocarditis (MC) and takotsubo cardiomyopathy (TC). Comparative data on mechanical circulatory support (MCS) utilization and outcomes...

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Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis

Atrial fibrillation (AF) is prevalent among patients undergoing transcatheter aortic valve replacement (TAVR) and increases risks of thromboembolism and bleeding with chronic anticoagulation. Concomit...

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Transfemoral Valve-in-Valve Transcatheter Aortic Valve Replacement in a Patient With Chronic Dissection Flap

Transcatheter aortic valve-in-valve implantation is an established therapy for failed surgical bioprosthetic valves and may obviate the need for reoperative surgery. Despite the routine use of large-b...

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Radial Artery Pseudoaneurysm Following Transradial Catheterization: Recognition, Management, and Prevention

Transradial cardiac catheterization is recommended over femoral artery catheterization for patients with acute coronary syndrome due to lower rates of bleeding and vascular complications. Despite its ...

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Early Clinical Experience with CrossFAST, a Novel, Microcatheter-Led Delivery System for Complex PCI

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An Evaluation of the Use of Fibrinolytic Therapy for Treatment of STEMI in Northern New England Over Two Decades

Geographic challenges complicate treatment of rural patients with ST-elevation myocardial infarction (STEMI), and many undergo a pharmacoinvasive (PI) strategy for optimal STEMI management. The PI pop...

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Pulmonary Embolism in the United States: A Report From the National PERT Consortium

Pulmonary embolism (PE) remains the third leading cause of cardiovascular-related mortality, and few efforts have been made to study it exclusively through real-world registry data. This research show...

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Incidence of Complications Following Coronary IVL, Clinical Outcomes and Predictors of Complications

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Economic Evaluations of Intravascular Imaging Guidance for Percutaneous Coronary Interventions: A Scoping Review

Intravascular imaging (IVI), including intravascular ultrasound and optical coherence tomography, has been associated with improved outcomes when used with angiography-guided percutaneous coronary int...

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Beyond Tunnel Length: Tunnel Width–Derived Cover Index Improves Device Sizing and Predicts Outcomes After Transcatheter Patent Foramen Ovale Closure

Residual shunting after transcatheter patent foramen ovale (PFO) closure occurs in up to 25% of patients and increases the risk of recurrent neurologic events. Existing sizing strategies may be insuff...

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Early Aspirin Discontinuation Following PCI for Acute Coronary Syndromes: A Systematic Review and Meta-Analysis of Reconstructed Individual Patient Data

Dual antiplatelet therapy (DAPT) is well-established for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Contemporary studies demonstrated that a short...

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Hybrid Suture- and Plug-Based Closure Versus Dual Suture Devices in Transfemoral Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-analysis

Effective vascular closure is crucial in transfemoral transcatheter aortic valve replacement (TAVR) to minimize access-related complications. Although dual suture-based closure is widely used, a hybri...

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Two-Year Clinical Outcomes in Patients With Coronary Bifurcation Lesions: Results From the Onyx ONE Clear Study

The optimal duration of dual antiplatelet therapy (DAPT) for high bleeding risk (HBR) patients undergoing percutaneous coronary intervention (PCI) can vary based on individual clinical and lesion char...

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Cost-Effectiveness of Supersaturated Oxygen Delivery for Infarct Size Reduction in Patients With Anterior ST-Segment Elevation Myocardial Infarction

Myocardial infarct size (IS) is a key determinant of long-term outcomes after acute myocardial infarction (MI). Although infusion of supersaturated oxygen (SSO2) after primary percutaneous coronary in...

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Evaluation of a Novel Antegrade-to-Retrograde Femoral Sheath Conversion System: A Preclinical, Cadaveric Study

Peripheral arterial disease often affects the lower extremities, is frequently bilateral, and typically involves multiple leg segments. Symptomatic disease is usually treated endovascularly. Antegrade...

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Reduced-Dose vs Full-Dose Direct Oral Anticoagulants for Extended Anticoagulation Therapy in Patients With Venous Thromboembolism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Extended anticoagulation therapy is often required in patients with venous thromboembolism (VTE), but the optimal dosing strategy remains unclear. This study aimed to evaluate the efficacy and safety ...

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