Xilma Ortiz-Gonzalez MD PhD

@drxilma.bsky.social

Boricua 🇵🇷 physician neuroscientist; Mom, Peds Neurogenetics 🧠🧬 @CHOP/UPenn, mitochondriac, my lab works on mechanisms of pediatric neurodegeneration #raredisease #TBCK https://www.med.upenn.edu/oglab/ opinion = my own

Astonishing. RFK Jr. adds 8 members to a 6 member FDA advisory panel. 6 of them were sellers of peptides, and the 7th a compounding pharmacist. In an 8-6 vote with all 8 votes coming from these new panel members, the panel approved 4 peptides against the objections of FDA scientists.

FDA Panel Supports Lifting Restrictions on Four Peptides (Gift Article)

In an all-day hearing, the agency’s scientists argued against allowing broad access to unproven drugs that the agency had banned three years ago.

nytimes.com

28 years of cyclosporiasis testing Screwworms eradicated in the US in 1966. Measles eradicated in the US in 2000. All are back because of this science denying administration.

Dr. Patricia Bath overcame sexism, racism & poverty and saved the sight of millions of people. She invented the Laserphaco Probe for cataract treatment, 1986; it was patented in 1988. She co-founded the American Institute for the Prevention of Blindness, 1976. She died #OTD in 2019. #WomenInSTEM

A vibrant color historical photograph capturing the brilliant ophthalmologist, inventor, and academic Dr. Patricia Era Bath (1942–2019) in an office or laboratory setting, radiating an aura of confident intelligence and warm approachability. Occupying the center and right of the shot, Dr. Bath sits facing forward, smiling brightly with a direct, engaging gaze at the camera. She is dressed in a professional white medical lab coat—subtly embroidered with "Dr. Bath" in red cursive on the left lapel—worn over a light blue button-down denim shirt and accented by a polished gold chain necklace. Pens are visible tucked into her left coat pocket. Positioned prominently to her right on the left side of the frame is a large, white medical laboratory microscope or ophthalmic imaging equipment with black eye-pieces. The background shows a white wooden bookshelf packed with colorful medical texts, binders, and stacked papers. This portrait carries immense historical significance, honoring a legendary trailblazer in STEM who became the first Black female doctor to patent a medical device—the revolutionary Laserphaco Probe for cataract treatment—fundamentally restoring sight to millions worldwide.

To be fair, my doctor also heals me by placing his hand on my forehead while holding a glowing orb in his other hand. I can tell the healing is working when my forehead also glows. He is also usually accompanied by angels, eagles and usually a fighter jet I can totally see how he’d confuse the two

Cancelling continuous submission for reviewers seems like just about the worst possible idea. grants.nih.gov/grants/guide... Unless of course breaking the system is the point. Many PIs are already quietly boycotting review. Some not wanting to lend credibility to an increasingly corrupted NIH…

NOT-OD-26-064: Update of NIH Late Application Submission Policy and End of Continuous Submission

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Update of NIH Late Application Submission Policy and End of Continuous Submission NOT-OD-26-064. NIH

grants.nih.gov

This story is insane. Married an American, arrested at her greencard interview, flown out of state, nearly killed multiple times when her diabetes was ignored and then mistreated. When she finally got out? Found out her credit card had been used illegally. www.daylightsandiego.org/san-diego-wo...

San Diego woman says her credit card information was stolen while she was in ICE custody

Hanne Engan, whom ICE arrested at her green card appointment, said her diabetes quickly escalated while at Otay Mesa Detention Center due to medical negligence. Written by Kate Morrissey, Edited...

daylightsandiego.org

Mariya Sweetwyne, an assistant prof at the University of Washington, is down to just 1 lab member after NIH rescinded a grant program through which she'd sought funding. She's reduced her mouse colony by half. Each morning, her daughter hands her a few coins and asks, “Is this going to be enough?”

Mariya Sweetwyne, an assistant professor at the University of Washington

Just a year ago, we heard reducing the deficit was so important Elon Musk had to fire as many scientists, forest rangers and Black women on the government’s payroll that he could find. Now? 🤷🏾‍♂️

Bild

The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.

Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302

There’s a seven year old boy hospitalized in Greenville, South Carolina with measles encephalitis. He can’t walk or talk or feed himself. This didn’t have to happen. Please vaccinate.