🎊 New Preprint from phagefoundry.org ! Super excited to share our latest work on generating systematic phage-MDR P. aeruginosa interaction dataset & use of ML to predict phage susceptibility & phage cocktails from target genome sequences alone, w validations www.biorxiv.org/cgi/content/...
Sarshad
@sarshad.bsky.social
Recent Me: Staring at a tube and a petri dish for months until the bacteria and their parasite start their own version of a soap opera. Just a professional spectator watching evolution play out in real-time, one barcode at a time.
📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.
Over the years I’ve tried many ways to sort color palettes. This is a compilation of different strategies: Hilbert curves, ΔE graphs, PCA, and TSP-style optimization: all trying to answer the same question: what is the “smoothest” order of colors? -> no clear winner: codepen.io/meodai/full/...
#microsky 🎊🎉 High resolution lineage tracking tech from Robin & Adam D team from Berkeley! 🙌 We have used this for phage-host interaction work too in the forthcoming preprint.
Very excited to share a big part of my dissertation work with the Deutschbauer lab at LBNL and @ucberkeleyofficial.bsky.social! BarTn7: A method for bacterial lineage tracking at sub-species resolution in population, ecological, and evolutionary experiments. www.biorxiv.org/content/10.1...
Today in @nature.com , we highlight how a cousin of CRISPR-Cas10, mCpol, establishes an evolutionary trap in anti-phage immune systems. Check out @erinedoherty.bsky.social and my work from @doudna-lab.bsky.social lab here: www.nature.com/articles/s41...
A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling - Nature
Panoptes, an anti-phage defence system against virus-mediated immune suppression, is revealed.
nature.com