Audrey Denizot
@adenizot.bsky.social
Inria research scientist interested in astrocytes #glia #neuroscience (she/her) https://team.inria.fr/aistrosight/ https://adenizot.github.io/
We're at @fens.org! #FENS2026 #FENSGlia Posters: PS02-07PM-558, PS03-08AM-495, PS05-09AM-674. Delighted to be presenting at the S44 Computational astroscience symposium on Thursday with T. Fellin, @anayebi.bsky.social & T. Papouin. Thanks @inbalgoshen.bsky.social for organizing, looking forward!
Exciting news! We are thrilled to announce that our proposal EU-GLIA has been selected for COST funding. EU-GLIA will build a pan-European network to advance nervous system health through glial cell research. #COST #EUGLIA #Neuroscience #GlialCells #EuropeanResearch
We're thrilled to share this #Perspective @natneuro.nature.com on #astrocytes as a multilayered system of #functional #units that operate across spatial scales. 👉Available for reading here: rdcu.be/fk0B7 👉Full article here: www.nature.com/articles/s41...
The multiple scales of astrocytic functional units - Nature Neuroscience
Astrocytes modulate complex brain functions. These ubiquitous glial cells constitute a multilayered system of functional units that operate across multiple spatial scales, thereby increasing the degre...
nature.com
An inspiring meeting in Braga with fantastic people resulted in a review article reflecting on the functional units of astrocytes across scales: lnkd.in/d4_epPtY. Very grateful to be part of this scientific journey. Many thanks to all authors & @joaofoliveira.bsky.social & @chenneberger.bsky.social
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lnkd.in
Delighted to share that we have 2 new preprints out from very talented PhD students. Schayma Ben Marzougui developed a new IP3R Bayesian model with multi-modal gating that accounts for exact missed-events. Florian Dupeuble developed a computational model of astrocyte-mediated neurovascular coupling.
Job alert! 🚨 We are recruiting an engineer to implement an open-source data hub of 3D cell reconstructions and meshes! More details here: lnkd.in/dq4sHRuC. Please reach out with a one page statement presenting your interests & a resume if interested #job #research #compneuro #engineer #neuroscience
Excited to share our new preprint! We explore the link between the locus coeruleus (LC) and arousal for astrocytes, pyramidal cells, interneurons in the hippocampus. A fantastic collaboration with @sianduss.bsky.social @bohaceklab.bsky.social, and many others: www.biorxiv.org/content/10.6... 1/5
We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues to measure axon size. The stretch-activated channel TMEM63A converts membrane tension into calcium signals, which cal...
cell.com
👉🏼👉🏾👉🏻👉🏿👉🏽An opportunity for a PhD studentship in my lab to investigate the mechanisms that mediate the specialization astrocyte endfeet (subcellular compartments enwrapping the vasculature) in collaboration with the magnificent Lorena Arancibia. See below:
Thrilled to announce that our study with C. Calı̀, Marifer Veloz, P. Puchenkov & @deschutteroist.bsky.social is out in #Glia! We explored the properties of the intracellular organization of astrocytes and how the latter influences astrocyte function at their interface with neurons 💫 bit.ly/4ql73Ul
Want to know how endoplasmic reticulum (ER) spatial structure affects calcium signaling in astrocytes? Check our new paper now online in Glia. The placement of IP3 receptors is crucial to determine whether ER close to the membrane amplifies calcium signals. onlinelibrary.wiley.com/doi/10.1002/...
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
Curious about the use of PDE discovery methods for mecanistic multiscale models of cell signaling? Check out our new benchmark paper, work by our amazing PhD student Andréa Ducos: hal.science/hal-05128224 First joint paper with @thomas-guyet.bsky.social! #modeling #PDEs #multiscale #cells #signaling
Sharmila Venugopal and I are delighted to co-edit a collection of video articles showcasing advances in computational neuroscience methods & software. There is still time to submit an abstract! More details here: app.jove.com/methods-coll... #compneuro #neuroscience #neuroinformatics #OpenScience
Big week for astrocyte research: 3 new Science papers link astrocytes to behavior. We're excited to add to the momentum with our new PNAS paper: a theory, grounded in biology, proposing astrocytes as key players in memory storage and recall. w/ JJ Slotine and @krotov.bsky.social (1/6)
Marseille is calling! 🇫🇷🌊☀️ Join us at #GLIA2025, where cutting-edge science on #glia cells meets the charm of the French Mediterranean. 📍 Marseille | 8–11 July 2025 🎥 Watch the GIF & get a taste of Marseille’s vibrant energy! 🌐 Register here: glia2025.eu
Revised preprint out! www.biorxiv.org/content/10.1... We show that most perisynaptic astrocytic processes contain calcium stores and identify the ultrastructural properties of the ER as key regulators of astrocyte function. With C. Calı̀, Marifer Veloz, P. Puchenkov & @deschutteroist.bsky.social
✨ Announcing a new glutamate indicator - iGluSnFR4! ✨ Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses. More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1... 🧠📈
Looking forward to this outstanding workshop on neural computation without neurons ⭐ Looking forward to presenting some new unpublished data on the influence of astrocyte ultrastructure on their function at the nanoscale in health and in #Alzheimer's disease. Extremely grateful for the invitation!
If you are around for the @cosynemeeting.bsky.social conference and interested in how neural computations happen in the brain without neurons (with astrocytes), drop by our workshop co-organized w/ @inbalgoshen.bsky.social and @leokoz8.bsky.social www.cosyne.org/workshops-pr...
🚨 Neuromatch Academy Course Applications are OPEN for 2025!! 🚨 Get your application in early to be a student or teaching assistant for this year’s courses! Applications are due Sunday, March 23. Apply & learn more: neuromatch.io/courses/ #mlsky #compneurosky #ai #climatesolutions #ScienceEdu 🧪
Version of Record of our work at @elife.bsky.social has been published! Super proud of this one after all the hard work of the lab seeing it to the end. Make sure to click through figure supplements as there is so much good stuff in there - sex differences, etc. elifesciences.org/articles/99988
Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation
Amygdala astrocytes play a critical role in mediating the effects of stress during infancy on neuronal excitability, synaptic plasticity, and memory.
elifesciences.org
Le Congrès Européen « XVII European Meeting on Glial Cells in Health and Disease » aura lieu à Marseille du 7 au 11 Juillet 2025. Le comité d’organisation lance un appel à candidature pour 10 volontaires pour une aide logistique lors du meeting !! Date limite : 8 février 2025 frenchglialcellclub.fr