Check our latest story about the control of cytokinetic abscission by Aurora B degradation! Congrats to Rayane and all coauthors! The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics: Current Biology www.cell.com/current-biol...

The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics

Dibsy et al. show that proteasomal degradation of the Aurora B kinase is required for cytokinetic abscission in human cells. Aurora B degradation reduces the phosphorylation of its substrate, CHMP4C, ...

cell.com

Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 https://www.embo.org/press-releases/embo-gold-medal-2026-awarded-to-gautam-dey-and-omaya-dudin/

There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant. research.pasteur.fr/en/call/mid-...

Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research

Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...

research.pasteur.fr

I am so proud of @jezcarlton.bsky.social . What a magnificent inaugural lecture, many congratulations Professor Carlton!

Honored to receive the 2025 #Sidaction Scientific “Young Researcher” Award. @sidaction.bsky.social Thanks to my supervisors & colleagues for their support. Inspired to receive this trophy from #Françoise #BarréSinoussi, Nobel Prize laureate, and motivated to keep contributing to scientific progress.

Excited to share that our paper is out in @natcomms.nature.com 🔗 rdcu.be/ez3Gt We uncover how MICAL1 regulates actin dynamics to enhance VWF–GPIbα binding in platelets. Big thanks to all co-authors & collaborators ! @hithlabinserm1176.bsky.social @echardlab-pasteur.bsky.social

F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets

Nature Communications - To stop bleeding from an injured vessel, platelets adhere and form a clot despite high shear stress from the flow. Here, the authors show that platelet actin disassembly is...

rdcu.be

Thrilled to receive the Peters Poster Award (Postdoc) at the 29th Young Researchers Meeting of the @fondationarc.bsky.social Grateful to the Fondation ARC, the jury, and donors for supporting my fundamental cancer research at @echardlab-pasteur.bsky.social ’s unit @pasteur.fr

Pour chaque vie, la science agit. Le Pasteurdon, c’est maintenant ! Soutenez la recherche et celles et ceux qui la font avancer ↘️ pasteurdon.fr #Pasteurdon

www.youtube.com/watch?v=hMH1... I am very thankful to the @ec.europa.eu for highlighting my research at @institutpasteur.bsky.social . It is a privilege for me to have the opportunity of developing my professional life here.

From Ancient Bones to Modern Insights: Argentinian Scientist Uncovering History of Disease in Paris

YouTube video by European Commission

youtube.com

The EMBO ESCRT meeting 2025 #EMBOescrt is open for registration: meetings.embo.org/event/25-escrt Please share the info around you, and see you in Montreux!

ESCRT function, evolutionary diversity and mechanism of action

The ESCRTs (Endosomal Sorting Complexes Required for Transport) were discovered in 2002 and became one of the most dynamic fields of research in membrane cell biology. ESCRTs are protein complexes fo…

meetings.embo.org

Finally out in Nature Chem Bio: SNAP-tag2 for faster and brighter protein labeling www.nature.com/articles/s41... Thank you Steffi and Veselin.

SNAP-tag2 for faster and brighter protein labeling - Nature Chemical Biology

SNAP-tag is a widespread tool for labeling protein for bioimaging. Now, Kühn et al. report SNAP-tag2 with increased labeling kinetics and brightness, which translates into a better performance in live...

nature.com

Beautiful cartoons on the grids of the Institute illustrating our future research centre on vector-borne diseases @pasteur.fr with lovely #trypanosomes and a tsetse fly 😉 Many thanks to Céleste Gangolphe for the exceptional work!

First official post! A new paper out about #cytokinesis in #epithelia www.embopress.org/doi/full/10.... Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.

Very excited that the lab's first paper is out! We showed that in stem cells, Aurora B controls abscission dynamics by regulating microtubules stability and MCAK recruitment. Very happy with this streamlined version of our 2024 preprint. www.cell.com/cell-reports...

Aurora B controls microtubule stability to regulate abscission dynamics in stem cells

Mouse embryonic stem cells remain connected by bridges for hours after cell division. In this paper, Kodba et al. show that a high Aurora B activity at the bridge leads to microtubule stabilization. S...

cell.com

Congrats!

Agathe Chaigne@agathechaigne.bsky.social · 2y ago

Very excited that the lab's first paper is out! We showed that in stem cells, Aurora B controls abscission dynamics by regulating microtubules stability and MCAK recruitment. Very happy with this streamlined version of our 2024 preprint. www.cell.com/cell-reports...

Dynamic duo at the cell's edge: Caveolae and the actin cytoskeleton work together to sense and respond to mechanical stress. Caveolae buffer tension, while actin provides structure and force. Ultimate biomechanics team. #CellBiology #Mechanotransduction

@institutcochin.bsky.social is opening a position for a scientist wishing to establish his/her independent team. Application deadline 21/01/2025. For details and application: institutcochin.fr/en/node/24264

Yamini @yamini-ravichan.bsky.social changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration: www.science.org/doi/10.1126/... Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.

What a sad news. Steve was an outstanding scientist and contributed greatly to midbody and centrosome biology. He was also a great colleague and an accomplished mountaineer. I will miss our scientific discussions and great hikes we did in Colorado. www.mercadantefuneral.com/obituaries/s...

Stephen J. Doxsey Obituary 2025 - Mercadante Funeral Home & Chapel

View Stephen J. Doxsey's obituary, send flowers, find service dates, and sign the guestbook.

mercadantefuneral.com

🧬 Save the date! The EMBO Workshop "The Immune System of Bacteria" will uncover groundbreaking insights into bacterial defense systems. Join us April 8-10, 2025, at Institut Pasteur, Paris. Submit your abstracts by Feb. 28 👉 https://www.sisb2025.conferences-pasteur.org/home

The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋 The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...

Institut Pasteur decides to leave X

The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...

pasteur.fr