🚨 Postdoc in 3D genome architecture – join the @jumanaaha.bsky.social lab at the MPI-IE, Freiburg (🇩🇪) The wonderful lab of Jumana AlHaj Abed is pushing the limits of how chromosomes fold and interaction – and we need someone who can code, image, & think across scales. Apply here: s.gwdg.de/9c8838

Attending #CellBio2025? Learn about "Providing constructive feedback in #PeerReview" tomorrow in Room 123 from 10–11:30 EST at the EMBO #training with speaker Sara Monaco, Managing Editor at Review Commons. 🧪 EMBO Lab Leadership

I am happy to share that my postdoctoral work in the @gerlichlab.bsky.social at @imbavienna.bsky.social is finally out 🎉! Our study reveals how cohesin guides focused and accurate homology search. Read more 👉 www.science.org/doi/10.1126/... Follow along for key insights and updates! 🧵

Cohesin guides homology search during DNA repair using loops and sister chromatid linkages

Accurate repair of DNA double-strand breaks (DSBs) is essential for genome stability, and defective repair underlies diseases such as cancer. Homologous recombination uses an intact homologous sequenc...

science.org

Excited to share our paper on dynamics of microcompartments during M-to-G1 is now published in @natsmb.nature.com www.nature.com/articles/s41... Compared to biorxiv, published includes new analysis from James Jusuf and Viraat Goel (from @andersshansen.bsky.social lab) on transcriptional spiking

Dynamics of microcompartment formation at the mitosis-to-G1 transition - Nature Structural & Molecular Biology

Goel et al. produce high-resolution three-dimensional genome structure mapping from mitosis to G1 phase to show unseen interactions between enhancers and promoters in prometaphase. Polymer modeling in...

nature.com

Ed Banigan@irate-physicist.bsky.social · 2y ago

been lurking here a while but time to spend less time in the bad place Here's my latest work in collab w/ Viraat Goel, @andersshansen.bsky.social, Leonid Mirny, Nick Aboreden, Gerd Blobel et al. Dynamics of microcompartment formation at the mitosis-to-G1 transition www.biorxiv.org/content/10.1...

We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab. www.biorxiv.org/content/10.1... 1/

Learn how the teams from @ninacabezas.bsky.social and our MPI-IE metabolomics facility created a metabolism map of healthy, old and cancerous HSCs. Great podcast episode. ⬇️🎧

Stem Cell Podcast@stemcellpodcast.com · last yr.

This week: the #metabolomics of HSPCs! A new @natcellbio.nature.com study from Drs. Marialena Lalioti, Mari Carmen Romero-Mulero, Joerg Buescher, and @ninacabezas.bsky.social identifies metabolic changes that occur with differentiation, aging, and #AML. 📝- go.nature.com/4kOZVLX 🎧- bit.ly/3IGfUP1

Max Planck Director Ibrahim Cissé has been elected to ​@embo.org. He is recognized for his outstanding research in biophysics & molecular biology. #EMBOmember www.ie-freiburg.mpg.de/6044802/2025...

Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪 Learn more here: www.embo.org/press-releas... #EMBOMembers2025

Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO

Sixty-nine new members join the community of leading life scientists in Europe and beyond

embo.org

📢The programme for #DDRCT25 is now available! Visit our website to explore the exciting sessions, speakers, and key topics we have in store. ➡️Check it out here: fusion-conferences.com/conference/177

Online Now: Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 Online now:

Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51

Merigliano et al. identified a non-canonical, “off-pore” role for nucleoporins in genome stability and in the spatial regulation of homologous recombination in multicellular eukaryotes. Nup98 condensates form at DNA breaks within pericentromeric heterochromatin to prevent aberrant recombination by excluding Rad51, while promoting the mobilization of repair sites through immiscibility with heterochromatin protein 1 (HP1) condensates.

dlvr.it