Almost 15 years after our initial observation that IRE1 is specifically active in cDC1s, we finally start understanding why… Check out the new study from @victor-bosteels.bsky.social, published in @natcomms.nature.com in press @https://rdcu.be/fur4Q
Victor Bosteels
@victor-bosteels.bsky.social
Marie Skłodowska-Curie Postdoctoral Fellow 🇪🇺 Fascinated by Dendritic Cell Biology. The Francis Crick Institute 🇬🇧 - Immunobiology Laboratory - Reis e Sousa Lab
Delighted to have written this Insight article together with @victor-bosteels.bsky.social and Will Stainier about a cool new story by Tam et al. And with a title to honour Jason Cyster’s heritage.
Rockefeller University Press@rupress.org · 9mo agoInsights @jem.org: Bosteels, Stainier, and @reisesousalab.bsky.social highlight work by Tam et al. (rupress.org/jem/article/...) revealing that GPR34, a lysophosphatidylserine receptor, promotes apoptotic cell uptake and cross-presentation by type 1 #DendriticCells. rupress.org/jem/article/...
Ever wondered how to deconvolute homeostatic from immunogenic mature dendritic cells by flow cytometry or by using transcriptional profiling?