The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning. Armstrong et al. 2025. EMBO J. 44:2620-2657. In collaboration with the Bieling and Hansen labs we reveal the steps leading to activation and retention of Rho GTPases at the plasma membrane.

Rho GTPase dynamics distinguish between models of cortical excitability. Chomchai, Leda et al. 2025. Curr Biol 35:1414-1421. In collaboration with the Goryachev and von Dassow labs, we test models proposed to explain cortical excitability--generation of propagating waves of rho GTPase activity.

Energy partitioning in the Cell Cortex. Chen et al. Nat. Phys. 2024. 20:1824-1832. This study--a collaboration with the Murrell lab--tracks the entropy production in the chemical (ie Rho GTPase) and mechanical (ie F-actin and myosin-2) subsystems of the cell cortex during cortical excitability.

Hi. We've been slow but the Bement lab (aka the Center for Xen Research) is finally on Bluesky.