This week we're talkin' about IV Sodium Bicarbonate in the ICU. 💉Does it improve mortality, MAKE30... or just pH? 🥤The SODa-BIC study #NephSky #MedSky www.nephjc.com/news/soda-bic
Buffering without benefit? The SODa-BIC study — NephJC
This week, we will discuss SODaBIC trial: with ICU acidosis driven by multiple overlapping mechanisms, is bicarbonate infusion supported by robust evidence, or does it persist mainly out of habit rath...
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🖌️Check out the #visualabstract for the SODa-BIC trial by @danyrcal.bsky.social #NephJC www.nephjc.com/news/2026/8/...
Hi, this is Assad , Nephrologist and transplant physician from India. No COI. We have a small cohort of transplant recipients whom we Flozinate, primarily for Proteinuria. #NephJC
T3d Benefits may vary, and results in the general population on CV risk and mortality are still controversial. Overall, the results of recent studies have been mixed results. Different study populations, end points and dosing may account for the lack of clarity. #NephJC
Hey I’m Assad, nephrologist working in a high-volume IgAN centre in India ! We’re still like the KDIGO guidleimes though - a bit outdated as we come up ! Probably it’s the cost of these drugs and their availability which limit us ! No COI #NephJC
Ongoing late posts from @theisn.org #ISNWCN from the high impact trial session - this was a great study design The India ALLIANCE GRACE IgAN trial Lead by Succeena Alexander from CMC Vellore #NephSky 1/
Treatment in children: 👶💉 Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases. #NephJC
Yes my exact opinion, guidelines may be evolving and improving but what happens in reality? Our patients either come with a creat of 8, Or they’re loaded with steroids for quite long without even SGLT2i or ARBs many times, and they’re just victims of therapeutic misadventure. Sorry state. #NephJC
Hey this is S M Assad, Assistant Prof Nephrology from CMC Vellore ! #NephJC In India, many with IgAN present late and do poorly—limited access, high costs, and low awareness keep outcomes far behind what they could be. Also the fact that the eGFR slope is somehow too deep. No COI
Hey this is Assad, nephrologist from Christian Medical College, Vellore in India. We tend to restrict proteins in our patients, and they go a few steps further stopping all protein altogether - ending up cachexic. Change is warranted. Most of our patients are traditionally vegetarian too🥑 #NephJC
a man in a suit and tie is eating broccoli from a person 's hand .
ALT: a man in a suit and tie is eating broccoli from a person 's hand .
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But I don’t see it going beyond the small privileged group of HLA matched patients ! There are too many IFs and BUTs involved #NephJC
The problem here is that - as attractive as being IS free sounds - it comes with a huge load right from patient selection, ensuring HLA compatibility, putting a huge burden on donors (making the MDR 101) and a very high risk IS withdrawal trial - with risk of rejection for the KTRs #NephJC
Check out the insightful summary by Dr Akshaya Jayachandran @nephromommy-akshu.bsky.social and Dr Natalia Nombera @roxnonna23.bsky.social #NephJC
Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression? — NephJC
This week, we will discuss the use of creating chimeras to induce immune tolerance and its potential to decrease or eliminate the need for immunosuppression in kidney transplant recipients.
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Hey, I'm S M Assad, young Nephrologist from CMC Vellore, India. No COI. While some centers in India have explored steroid-free regimens and local stem-cell work, the complexity and cost of bespoke cell therapies mean we rely on conventional, cost-effective IS as the standard of care. #NephJC
It was. The book is focuses on the history of TB, but it’s definitely not historical. In India, it’s our present. TB plagues all communities and classes, and it’s probably nothing to be proud of, that I seem to know and see most of these situations day-in and out ! #NephJC
Beautiful and meaningful poem by @nephromommy-akshu.bsky.social inspired by @johngreensbluesky.bsky.social's Everything is Tuberculosis www.nephjc.com/news/2025/8/...
#NephJC Summer Book Club Everything Is Tuberculosis poetry — NephJC
Akshaya Jayachandran, NephJC intern was inspired by John Green’s Everything is Tuberculosis to write the following poem.
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On 7/22/25 at 9pm EST only on Bluesky! #NephSky #MedSky join us for a lively discussion. We're debating eGFRdiff (the gap that is sometimes present between the eGFR of cystatin C and creatinine). What does it mean, what causes it and what you should do about it. #NephJC www.nephjc.com/news/egfrdiff
Mind The Gap: When eGFR Creatinine and Cystatin C Disagree — NephJC
This week, we will discuss the clinical significance of eGFRdiff, the difference in eGFRcys (cystatin C) and eGFRcr (creatinine).
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Check out the VA from @drsaivani.bsky.social and @nephromommy-akshu.bsky.social on eGFRdiff in the CRIC cohort. #Nephsky #NephJC www.nephjc.com/news/cricdiff
Insights from the CRIC Study: Visual Abstract — NephJC
Based on data from the CRIC study, this analysis dives deep into whether this lab mismatch is just noise… or a clinical signal we’ve been missing. Check out the beautiful visual abstract made by our NephJC interns Sai Vani Yellampalli and Akshaya Jayachandran . Great team work!!!
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Hi I’m Assad, practising nephrologist from India, Flozinator but not a finerator (yet) ! My first #NephJC chat ! No COI
Attended #KSN2025 in Seoul 🇰🇷! Presented two posters at the conference! 👩🏻⚕️ A scintillating experience soaking in all the science, savouries and Seoul skies !! 😃🎏🥋🍜@assadsm.bsky.social #nephrology #KSN #seoul #nephroconference
Attended @ksnmeeting 2025 at Seoul and had the opportunity to present my poster at the conference! Thrilled by the city’s vibrant cultural and modern landscape!! @nephromommy-akshu.bsky.social #nephrology #KSN #seoul #nephroconference
Welcome next #NephJC generation! New NephJC authors & creators debuting in July 2025, check them out & give them a follow! 📸 Team A: @sejalplakhani.bsky.social @notjustdialysis.bsky.social @msocomd.bsky.social @shelliefravel.bsky.social @salinesolut.bsky.social @jeyakimarmeyyappan.bsky.social
