@mcb-sheffield.bsky.social
Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships to join our friendly & collaborative environment, in areas related to gene expression, mechanistic cell biology & cancer biology. For more info 👇 sheffield.ac.uk/biosciences/...
Proud to have been awarded LEAF Silver (again) - with @helenkmatthews.bsky.social lab!! @mcb-sheffield.bsky.social
📢 PhD opportunity: fully-funded BBSRC Yorkshire Bioscience project available @mcb-sheffield.bsky.social Interdisciplinary project on keratins in cell division combines cell biology, biophysics and in vivo Zebrafish imaging. 👇Apply by 7th Jan www.findaphd.com/phds/project...
BBSRC Yorkshire Bioscience DLA Programme: The role of keratin networks in cell division in tissues under tension at University of Sheffield on FindAPhD.com
PhD Project - BBSRC Yorkshire Bioscience DLA Programme: The role of keratin networks in cell division in tissues under tension at University of Sheffield, listed on FindAPhD.com
findaphd.com
📣 Paper alert: Ras signalling at the actin cortex: Coordinating local and global changes to cell morphology. @helenkmatthews.bsky.social pubmed.ncbi.nlm.nih.gov/41275567/
Ras signalling at the actin cortex: Coordinating local and global changes to cell morphology - PubMed
Ras proteins modulate key cellular signalling pathways and drive excessive proliferation when mutated in cancer. However, they also influence actin cytoskeleton organisation. In the model organism Dictyostelium, domains of active Ras pattern the plasma membrane and locally reorganise the actin corte …
pubmed.ncbi.nlm.nih.gov
📢 Paper alert: Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development. pubmed.ncbi.nlm.nih.gov/41347775/
Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development - PubMed
In developing epithelia, cells become planar polarised through asymmetric localisation of the core planar polarity proteins to opposite cell membranes, where they form stable intercellular complexes. Current models differ regarding the signalling mechanisms required for core protein polarisation. He …
pubmed.ncbi.nlm.nih.gov
Our external seminar speaker today will be Alexandra Davies, PhD from the University of Manchester "Location, location, location: subcellular spatial proteomics to map protein localisation in neurodegenerative diseases" 📍 Alfred Denny Conference Room 📅 3rd December - 1pm
We are delighted to host Juan Martin-Serrano today from @kingscollegelondon.bsky.social "Genome protection by the ESCRT machinery" 📍 Alfred Denny Conference Room 📅 19th November - 1pm
📣 Fully funded PhD position available in collaboration with @jasonkinglab.bsky.social in @mcb-sheffield.bsky.social BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? 📅 Deadline: 7th January 2026 More info 👇 www.findaphd.com/phds/project...
BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? at University of Sheffield on FindAPhD.com
PhD Project - BBSRC Yorkshire Bioscience DLA Programme: How do cells coordinate nutrient scavenging pathways? at University of Sheffield, listed on FindAPhD.com
findaphd.com
Our external seminar speaker today will be Peter Hill from @kingscollegelondon.bsky.social "How host-pathogen interactions can inform therapeutic strategies against relapsing invasive non-typhoidal Salmonella infections" 📍 Alfred Denny Conference Room 📅 5th November - 1pm
📢 Fully-funded 4-year MRC DiMeN PhD opportunity in our lab. 🔬 Exciting cancer cell biology collab with @maiblab.bsky.social & Liz Smythe @mcb-sheffield.bsky.social to use recombinant biosensors to image active KRAS in #pancreaticcancer 👇Apply by 4th Dec www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Understanding the membrane recruitment of oncogenic KRAS in pancreatic cancer at University of Sheffield on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Understanding the membrane recruitment of oncogenic KRAS in pancreatic cancer at University of Sheffield, listed on FindAPhD.com
findaphd.com
We are delighted to host Prof Rob deBruin from @ucl.ac.uk today "Targeting Cell Cycle Control in Cancer" 📍 Alfred Denny Conference Room 📅 22nd October - 1pm
We are delighted to host Harsha Kantamneni today from the University of Bradford. "Endosomal Sorting Complex Required for Transport (ESCRT): Roles in receptor trafficking, signalling pathways, drug resistance and disease" 📍 Alfred Denny Conference Room 📅 18th October - 1pm
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share. www.jobs.ac.uk/job/DOW912/s...
Senior Research Technician at University of Birmingham
Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
jobs.ac.uk
Congratulations to Shahd on passing her PhD viva!!!! Thanks to Christoph and Jason @jasonkinglab.bsky.social for examining
More fascinating talks this morning by our final year students Megan Poxon (@jasonkinglab.bsky.social & @helenkmatthews.bsky.social), Nada Alosaimi (C. Smythe lab), Zhe Bao (@erainerolab.bsky.social), @rlawson954.bsky.social @helenkmatthews.bsky.social) and Ashleigh Whelan (Wilson lab)
Great talks by our @mcb-sheffield.bsky.social speakers Grace Gilbert (@bose-lab.bsky.social & @tsakiridis.bsky.social), Francesca Brown (Humphreys lab) and Rob Hunton (@struttlab.bsky.social) at the 3rd year PGR symposium!! Back tomorrow morning - stay tuned!!
Here are our fantastic postdocs: Mona, Rachele & Eric @mcb-sheffield.bsky.social #NPAW2025 #PostdocAppreciationWeek
Well done to our PhD student @rlawson954.bsky.social 👏 on giving a talk on her data on keratins and mitotic mechanics at the MBI-MPG conference at @mbisg.bsky.social in Singapore! @mcb-sheffield.bsky.social
Mechanobiology Institute@mbisg.bsky.social · last yr.What happens to packed cells in a monolayer during mitosis? @rlawson954.bsky.social presented varying experiments investigating shape and force changes, cell-cell junctions, and mechanics in mitotic cells, suggesting important roles for keratin and desmosomes #MBIMPG2025 @helenkmatthews.bsky.social
Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on! www.path.ox.ac.uk/work-with-us...
Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
path.ox.ac.uk
Interested in Pancreatic Cancer Research? We are gearing up to host our 7th Sheffield Pancreatic Cancer Research Network meeting! Check out the details at: sites.google.com/sheffield.ac... @mcb-sheffield.bsky.social @fohsheffield.bsky.social
Sheffield Pancreatic Cancer Research Network - Events
Upcoming Events
sites.google.com
Calling all meeting organizers… @biologists.bsky.social now have a calculator to estimate your event’s carbon footprint and to test various reduction scenarios. thenode.biologists.com/event-carbon...
Event carbon calculator - the Node
I am excited to announce the release of our event carbon calculator, our latest resource to support the creation of sustainable events. Estimate your
thenode.biologists.com
🚨 JOB ALERT 🚨 We're hiring a Research Assistant – no PhD needed! Join us to explore the molecular mechanisms of receptor sorting in endosomes. Experience in protein expression/purification, cloning & cell culture desired 🧫🔬 Apply now 👉 www.nature.com/naturecareer... #STEMCareers #ResearchJobs
It was a pleasure to visit @sheffielduni.bsky.social last week presenting our work "Neutrophil metabolism faciliates metastasis by influencing immune & ECM landscapes" at @mcb-sheffield.bsky.social seminar series.Thanks @erainerolab.bsky.social for the invitation & all who made it a memorable visit
I am excited to share our new Sheffield Pancreatic Cancer Research Network website! Please check it out at... sites.google.com/sheffield.ac... @fohsheffield.bsky.social @mcb-sheffield.bsky.social
Sheffield Pancreatic Cancer Research Network
Meet the Team
sites.google.com
We are delighted to host @cassiejclarke.bsky.social today from the @cruk-si.bsky.social! "Neutrophil metabolism supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes" 📍 Alfred Denny Conference Room 📅 10th June - 1pm
📣 Postdoctoral position available!!! Are you interested in translating molecular cell biology into potential cancer therapy? This project will explore the role of EGFR trafficking in chemotherapy resistance in #breastcancer 🔬 Prof Liz Smythe lab 📅 Deadline: 3rd Jule 👇 www.jobs.ac.uk/job/DNJ622/r...
Research Associate (Cell Biology) at University of Sheffield
An opportunity for an academic position as a Research Associate (Cell Biology) is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
jobs.ac.uk
New addition to our lab's PhD Wall of Fame - Bian 🇸🇾 #WeAreInternational @mcb-sheffield.bsky.social @sheffielduni.bsky.social
Hot off the press for your Friday morning! 🔥 Our new (and highly revised!) preprint is out. It significantly expands on our previous work, unveiling exciting new data on how CBP's intrinsically disordered regions (IDRs) regulate genes. Link to preprint: tinyurl.com/5npjkyps #IDRs #condensates #CBP
CBP-IDRs regulate acetylation and gene expression.
Intrinsically disordered regions (IDRs) have emerged as crucial regulators of protein function, allowing proteins to sense and respond to their environment. Creb binding protein (CBP) and EP300 (p300)...
tinyurl.com
