Dr David Joffe MB BS(Hons), PhD, FRACP
@davidjoffe64.bsky.social
Respiratory and Sleep Medicine Neurobiology and Long Cövid Vice President of ISLC & PAIS
Fascinating Sleep Science Effects of a multimodal intervention for optimising sleep and internalising symptoms in young adults during British Army Infantry Basic Training academic.oup.com/sleep/articl...
The effects of a multimodal intervention for optimising sleep and internalising symptoms in young adults during British Army Infantry Basic Training
Sleep disturbance remains pervasive during military training, underscoring the challenge of translating sleep optimisation policy into practice. This multi
academic.oup.com
Not a human study, but definitely noteworthy 👀 β-Cells make insulin Post C-19 Diabetes is not uncommon. doi.org/10.1038/s413...
SARS-CoV-2 seeds IAPP aggregation and β-cell failure - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - SARS-CoV-2 seeds IAPP aggregation and β-cell failure
doi.org
🧠 Daily Feed of Brain Damage 🧠 From my endless resource @atranscendedman.bsky.social 🙏🏻 doi.org/10.1093/brai...
A cognitive architecture for Long COVID: the interplay of brain fog, fatigue, attention and memory
Higgins et al. report findings from a large dataset of COVID-19 patients. The findings show deficits in memory and attention specific to patients with Long
doi.org
Then there's this from the Italian Group. Presented in Amsterdam at a session I was lucky enough to be chairing 😎 pmc.ncbi.nlm.nih.gov/articles/PMC...
VSL#3® supplementation improves fatigue in long COVID: results from the DELong#3 randomized placebo-controlled trial
Long COVID is frequently characterized by persistent fatigue and impaired quality of life. Increasing evidence suggests that gut microbiota dysbiosis and immune dysregulation may contribute to symptom...
pmc.ncbi.nlm.nih.gov
Dr David Joffe MB BS(Hons), PhD, FRACP@davidjoffe64.bsky.social · 6d agoThe best study thus far is with BA-21 Mexican study
Cite this article Herrera, E., Señoráns, A., Barrenechea, A. et al. Cognitive phenotypes and neuropsychological trajectories in post-COVID-19 syndrome: a 12-month follow-up study. Sci Rep (2026). doi.org/10.1038/s415...
Cognitive phenotypes and neuropsychological trajectories in post-COVID-19 syndrome: a 12-month follow-up study - Scientific Reports
Scientific Reports - Cognitive phenotypes and neuropsychological trajectories in post-COVID-19 syndrome: a 12-month follow-up study
doi.org
Carole Bell@carolebell.bsky.social · 6d agoSuch a pity that doi.org, of all entities, makes it hard for people to reject cookies. When that happens, it's their loss. I just don't repost or forward. It's my loss too because I can't read it.
🧠 Daily Feed of Brain Damage 🧠 @atranscendedman.bsky.social 🙏🏻 doi.org/10.1038/s415...
Cognitive phenotypes and neuropsychological trajectories in post-COVID-19 syndrome: a 12-month follow-up study - Scientific Reports
Scientific Reports - Cognitive phenotypes and neuropsychological trajectories in post-COVID-19 syndrome: a 12-month follow-up study
doi.org
For those following this substantial medical conundrum... And... For those following this account Thank you 😊🙏🏻 doi.org/10.1155/jimr...
Characterizing Host Inflammatory Bioprofiles in People With Postacute Sequelae SARS‐CoV‐2 Infection (PASC)
Postacute sequelae of COVID-19 or “PASC” is a common but heterogeneous condition associated with significant morbidity. Although its pathogenesis remains poorly understood, proposed underlying mechan...
doi.org
You just gotta love a company so fucked up, they cannot find your email to re-instate your prior account... BUT... They can find you when @elonmusk needs my $Au12... What a Shit Head 😂😂
I'm not the Person to follow for a pile of shits and giggles... Thank you for sharing 🙏🏻 I appreciate the understanding and yep... I'm here for those with an interest and concerns
His Royal Huwness 🏴🐸🇵🇸🇪🇺@litterygeniarse.bsky.social · last wk.Decidedly short on laughs. But shared for those who may be interested.
Ummmm.... So just when you thought your Long Covid was bad? "Orgasmic Cephalgia" enters the chat😳 doi.org/10.1093/sxmr...
Post-orgasmic illness syndrome: possible role of mast cells, immunoglobulins, and multi-organ system inflammatory response
AbstractIntroduction. Post-orgasmic Illness Syndrome (POIS) is an incapacitating reaction that erupts following ejaculation/orgasm. The reaction occurs in
doi.org
"77.4% continued to meet PCC criteria in 2024" doi.org/10.1038/s415...
Factors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection - Scientific Reports
Scientific Reports - Factors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection
doi.org
And my colleagues wonder why I protest in favour of masks in Health Care 😔💔 doi.org/10.1136/bmj-...
Covid-19: 40% of affected healthcare workers had long covid, and a quarter still had symptoms after a year
Four in ten healthcare workers worldwide who were infected with SARS-CoV-2 during the pandemic developed long covid, and a quarter still had symptoms after a year, a report has found. The report by t...
doi.org
link.springer.com/article/10.1...
Health-related quality of life in IBD patients with long COVID under China’s normalized COVID-19 management - BMC Infectious Diseases
Introduction Although the COVID pandemic has gradually subsided, many patients have experienced complicated long-term symptoms, collectively known as “long-COVID”, which is commonly associated with pe...
link.springer.com
🧠 Daily Feed of Brain Damage 🧠 Part 2 The gift that keeps giving 👀 doi.org/10.1038/s415...
Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction - Nature Medicine
A national prospective study of patients requiring hospitalization for COVID-19 demonstrates global cognitive deficits at 1 year, associated with elevated brain injury markers and reduced gray matter ...
doi.org
You're absolutely right, Steve🙏🏻😊 My apologies... The puppies were having a bath... Chaos ensued 😂😂
Steve Fifield@stevefifield.bsky.social · 2w agoYou originally posted: www.mdpi.com/2673-4087/7/...
🧠 Daily Feed of Brain Damage 🧠 In case you're wondering why people have "attitude" and anger issues 😳 doi.org/10.3390/neur...
Useful paper. Consider hypocarbia when you see POTS. At least it's a treatment responsive cause of breathlessness👍🏻 www.mdpi.com/2077-0383/15...
Metabolic derangement following acute infection... Possibly a predictor of LC going forward. Only COVID causes Long C-19 doi.org/10.1016/j.di...
Things that don't improve over time pubs.rsna.org/doi/10.1148/...
Five-year Quantitative Chest CT and Hyperpolarized Xenon 129 Ventilation MRI Findings in Survivors of COVID-19 Pneumonia | Radiology
Five years after COVID-19 pneumonia, some survivors showed persistent respiratory symptoms, abnormal diffusion capacity, and ventilation defects, with stabilization of pulmonary function and chest ...
pubs.rsna.org
Elegant study from @profmarkfaghy.bsky.social and his outstanding Team.... Now in ink🖋😎 doi.org/10.1093/oxfi...
An Open-Label Feasibility Study of Remdesivir in Long COVID: Results from the ERASE LC Trial
AbstractObjective. Treatment of acute COVID-19 with anti-viral and immunomodulator medications demonstrates a reduced risk of long-term outcomes. To date,
doi.org