EVBO congratulates our board members, Katrien de Bock and Taija Mäkinen, on receiving their ERC Advanced Grants!

Glad to see @jci.org featuring our study on endothelial RTK/integrin crosstalk—where ANGPT2 simultaneously engages two receptors! Big thanks to @johannaivaska@bsky.social and all co-authors and funders. @HelsinkiUniMed @helsinkiuni doi.org/10.1172/JCI1... #vascularbiology

Journal of Clinical Investigation@jci.org · 2mo ago

Inactive β1-integrin acts as a junctional scaffold for angiopoietin/TIE2/FOXO1 signaling: doi.org/10.1172/JCI1...

Calling all vascular biologists! Join us for cutting edge science at #Angioscience26 in gorgeous Seeon, Bavaria. Awesome speakers, intimate setting, many talks from abstracts. Deadline June 15th to register! vwfb.de/start/regist...

Irena Roci et al. @petrovalab.bsky.social show that the water channel AQP1 sustains lymphatic endothelial cell migration under osmotic stress, establishing tissue #osmolarity as a key biophysical determinant of postnatal #lymphangiogenesis. rupress.org/jem/article/... #lymphatics #AQP1

Happy to share that our latest work on VEGFR2 in lymphatic endothelium is published @natcomms.nature.com “VEGFR2 is required for VEGF-C–VEGFR3–PI3Kα-mediated sprouting lymphangiogenesis” tinyurl.com/47bns9pp This project has been a long journey for the lab @taijamakinenlab.bsky.social , A thread.

We are offering 5 Postdoc Positions within the Max Planck Postdoc Program! Take advantage and apply by April 13, 2026 to the positions in the labs of @ralfhadams.bsky.social, @ruibenedito.bsky.social and @katemiro.bsky.social. Link to our website: www.mpi-muenster.mpg.de/max-planck-p...

The Max Planck #PostdocProgram offers top emerging talents a range of attractive measures and opportunities. The current call for applications is open from March 1st until April 13th, 2026. Please share or consider applying! 🙏 www.mpg.de/en/max-planc... #careerinscience #sciencecareer

Veins in the skull can rearrange their borders to accommodate patrolling immune cells go.nature.com/4tLrKul

How ‘skull drains’ keep the brain safe from damage and pathogens

Nature - Veins in the skull can rearrange their borders to accommodate patrolling immune cells, a strange behaviour called ruffling.

go.nature.com

Job alert: eur04.safelinks.protection.outlook.com?url=https%3A...

Postdoctoral and doctoral positions to study Immune–Endothelial Interfaces - European Vascular Biology Organisation

Postdoctoral and Doctoral positions are available in the newly established Finnish Centre of Excellence in Immune–Endothelial Interfaces (IMMENs), composed of four research groups: Dr. Taija…

eur04.safelinks.protection.outlook.com

Thrilled to kick off our Centre of Excellence on Immune–Endothelial Interfaces (IMMENs), funded by the Research Council of Finland, with the first meeting in Helsinki! Great to start this journey with Kari Vaahtomeri, Cecilia Sahlgren and Guillaume Jacquemet @guijacquemet.bsky.social.

Our new study is out! 🎉 Driven by MD‑PhD Ludivine Bersier, our work shows how chemotherapy‑induced gut injury creates a systemic “chemomemory” that protects against colorectal cancer (CRC) liver metastasis. 🔗 doi.org/10.1038/s414... 🧵 Thread 👇

We’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells. www.nature.com/articles/s41...

Convergent evolution of scavenger cell development at brain borders - Nature

Transcription factor osr2 is identified as a specific marker and regulator of mural lymphatic endothelial cell (muLEC) differentiation and maintenance, and muLECs and border-associated macrophages sha...

nature.com

We have asked the new EMBO Members to tell us about themselves and what makes it so compelling to work in #science today. 🧪 In the eighth video of the series, EMBO Members tell us what part of their #research process they enjoy the most and why. #LifeSciences

❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more! www.nature.com/natcardiovas...

I am honoured to be elected as a Member of EMBO and look forward to contributing to its mission and community!

EMBO@embo.org · last yr.

Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪 Learn more here: www.embo.org/press-releas... #EMBOMembers2025

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in ‪@natcardiovascres.nature.com by Marle Kraft et al. rdcu.be/enhST

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations

Nature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth...

rdcu.be

📢 #GRC_Angiogenesis program is up! We have an amazing lineup of speakers ready to dive into the "social life" of vessels! How they engage with their neighbors, how they connect, and why they break up! Plus we have ~15 slots available for short talks! Apply (link 👇) and see you in Newport in July!

Not every organ ages the same🤠 With Age, Skull bone marrow Vasculature+HSPC Expand & ⏫ contribution to peripheral leukocyte Skull BM expands with Pregnancy CML PTH Stroke @bikohcello.bsky.social @vishalmkrishnan.bsky.social @ralfhadams.bsky.social @nature.com 2024 www.nature.com/articles/s41...

I am a bit biased, but check out the beautiful work and thread by @hansschoofs.bsky.social @taijamakinenlab.bsky.social on why lymphatic endothelial cells have their jigsaw puzzle-like shape 😍😍😍

Hans schoofs@hansschoofs.bsky.social · last yr.

• Happy to announce that our paper in @nature.com is finally out! Thanks to the perseverance of @taijamakinenlab.bsky.social and our many collaborators we finally pulled it off! A small 🧵 www.nature.com/articles/s41... Laymen video: www.nature.com/articles/d41...

My lab at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany offers postdoc positions in stem cell mechanobiology. www.mpi-muenster.mpg.de/departments/... drop me an email

Cell and Tissue Dynamics (Wickström)

mpi-muenster.mpg.de

#EVBOSummerSchool 2025: Please help spread the news! 10-11 June 2025 | Biomedicum Helsinki, Finland Registration will open soon. Stay tuned! The summer school will be preceded by the excellent and free-of-charge Wihuri Research Symposium on Cardiovascular Biology! More info buff.ly/42I9fvY

Type R capillary #EndothelialCell in Bone Cav1+ Efnb2+Flt4-Emcn+ B/w Sinusoid EC & Artery 👉Close to trabecular🦴 osteoprogenitor osteoclast 👉Angiocrine SEMA7A+ ⏫by #Aging anti-osteoporosis therapy @vishalmkrishnan.bsky.social l @ralfhadams.bsky.social #NatCellBio 2024 www.nature.com/articles/s41...

Blood vessels in the brain rhythmically constrict and dilate to drive waves of cleansing fluid through the organ https://go.nature.com/3PwtwN2

How the brain cleans itself during deep sleep

Blood vessels in the brain rhythmically constrict and dilate to drive waves of cleansing fluid through the organ.

go.nature.com

Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)

The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes

Nature Metabolism - Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.

rdcu.be

Aaaaand finally: #NCB2024 In November, @ralfhadams.bsky.social & co identified a distinct subset of post-arterial #capillaries, termed type R, which contribute to trabecular #bone formation in the diaphysis and respond to anti-#osteoporosis treatments. www.nature.com/articles/s41...

Specialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell Biology

Mohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to ...

nature.com

Pleased to share the work of Mitzy Cowdin and others in our lab showing the requirement for the Hippo pathway kinases Lats1 and 2 for endothelial sensing of hemodynamic flow and for vascular remodeling during embryogenesis 🎉🧪 www.biorxiv.org/content/10.1...

Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress

Blood vessels in mammalian embryos develop from initial aggregates of endothelial cell (EC) progenitors, which coordinate the opening and stabilization of central vascular lumens, all while under prog...

biorxiv.org

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/

🥂Congratulations to @ralfhadams.bsky.social @vishalmkrishnan.bsky.social & co for their new Open Access study in our journal (@naturecellbiology.bsky.social) identifying type R #capillaries and showing their role in trabecular #bone formation in the diaphysis. www.nature.com/articles/s41...

Specialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell Biology

Mohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to ...

nature.com

Happy #FluorescenceFriday

💫NEW: @ralfhadams.bsky.social & co identify a distinct subset of post-arterial #capillaries, termed type R. They show that type R capillaries contribute to trabecular #bone formation in the diaphysis and respond to anti- #osteoporosis treatments. www.nature.com/articles/s41...

Specialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell Biology

Mohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to ...

nature.com