🧬🧬🧬It’s all in your DNA: damage in the DNA accumulates and drives aging. Could mending damaged DNA prolong life? News featuring the DREAM master regulator of DNA repair today in @Nature www.nature.com/articles/d41...

Could mending damaged DNA prolong life?

Inspired by long-lived animals — and human centenarians — researchers are hunting for ways to enhance DNA repair and extend healthspan.

nature.com

Connecting fragmented aging research through the European Federation for Aging Research | Nature Aging. Read here how EFAR will provide a new platform for the geroscience community ⁦‪Morten Scheibye-Knudsen ‬⁩, Lene Rasmussen, Folkert Kuipers www.nature.com/articles/s43...

Check out our new review article on Beyond the mouse: 3R-guided alternative animal models transforming cancer research link.springer.com/article/10.1... Great collaboration with @amatrudalab.bsky.social @bjornschumacher.bsky.social & Tobias Reiff

🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe...

“One of the Greatest Challenges of Our Time”: Preventing Neurodegeneration | Technology Networks www.technologynetworks.com/neuroscience...

“One of the Greatest Challenges of Our Time”: Preventing Neurodegeneration

In a new study, an aging clock has revealed neuron-specific aging, as well as potentially neuroprotective compounds.

technologynetworks.com

🚀Our new preprint:🧠Neuronal 🧬DNA 🧬repair mediates systemic mitochondrial maintenance through acetylcholine signaling. Neuronal repair is sufficient for the overall health amid DNA damage! @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social www.biorxiv.org/content/10.6...

How Aging clock reveals molecules that protect against neurodegeneration healthmedicinet.com/aging-clock-...

Do natural substances from blueberries and blue grapes protect nerve cells from aging?A www.bionity.com/en/news/1188...

Do natural substances from blueberries and blue grapes protect nerve cells from aging?

Using an aging clock, researchers from the University of Cologne have used the Caenorhabditis elegans model organism to demonstrate that nerve cells age differently. They identified both the cause ...

bionity.com

A clock that measures the aging of nerve cells finds molecules that protect against age-related neurodegeneration | EurekAlert! www.eurekalert.org/news-release...

A clock that measures the aging of nerve cells finds molecules that protect against age-related neurodegeneration

Using an aging clock, researchers from the University of Cologne have used the Caenorhabditis elegans model organism to demonstrate that nerve cells age differently. They identified both the causes of...

eurekalert.org

🚨Thrilled to share this exciting new paper by our #FOR5762 project leader @bjornschumacher.bsky.social, published in #NatureAging! The study uncovers neuron-specific aging patterns and points to potential neuroprotective interventions. Congratulations! 🎉 www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging

Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

nature.com

To elucidate whether diff. neuron types differ in their biological aging process, researchers applied "BitAge" (binarized transcriptomic age clock) to 128 different neuron types in C. elegans & found that distinct neurons differ in their biological age www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging

Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

nature.com

🧠 Nerve cells age differently Researchers led by @bjornschumacher.bsky.social‬ @cecad.bsky.social have used C. elegans to prove for the first time that nerve cells age differently. Using an “aging clock” they were able to precisely determine the biological age of individual neurons👇 uni.koeln/FKJ35

⏰🧠 Nervenzellen altern unterschiedlich Forschende um @bjornschumacher.bsky.social @cecad.bsky.social haben in C. elegans erstmals nachgewiesen, dass Nervenzellen unterschiedlich altern. Mit einer „Alternsuhr“ konnten sie das biologische Alter einzelner Neuronen präzise bestimmen👇 uni.koeln/BWMMP

Eine Alternsuhr der Nervenzellen findet Moleküle, die vor altersbedingter Neurodegeneration schützen www.idw-online.de/-DTSBAA

Big thanks to @bjornschumacher.bsky.social for his guidance and all co-authors. This was a great team effort. Paper: www.nature.com/articles/s43... (9/n) #aging

🚨Publication Alert🚨 New work from our #CRC1678 members @bjornschumacher.bsky.social and @meyerdh.bsky.social reveals why some neurons age faster. Using neuron‑specific aging clocks, they identified vulnerable neurons and highlight syringic acid and vanoxerine as promising neuroprotective hits.🧬

David Meyer@meyerdh.bsky.social · 6mo ago

Why do some neuron types degenerate early while others stay intact? We used transcriptomic aging clocks for single-neuron-types in C. elegans and found neuron-specific biological age predicts vulnerability. 🧪 www.nature.com/articles/s43... #Neurodegeneration 🧵👇 (1/n)

Why do some neuron types degenerate early while others stay intact? We used transcriptomic aging clocks for single-neuron-types in C. elegans and found neuron-specific biological age predicts vulnerability. 🧪 www.nature.com/articles/s43... #Neurodegeneration 🧵👇 (1/n)

🧠⏰our latest paper is out now: how each neuron ages differently allowed us to define in silico screens for new therapeutic molecules that could prevent neurodegeneration @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social @meyerdh.bsky.social www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging

Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

nature.com

Curious about the role our genetic traits 🧬 and our lifestyle 🏄‍♀️ play in healthy ageing? In the latest episode of the Bild der Wissenschaft podcast, our #CRC1678 project leader @bjornschumacher.bsky.social explains the science behind longevity! 🎙️Listen here: www.wissenschaft.de/gesundheit-m...

Bild der Wissenschaft PODCAST – Folge 13: Ein Autopilot für Schiffe

Cyril Alias erklärt, wie ein Autopilot Binnenschiffe durch Flussbiegungen und Stromschnellen navigieren könnte.

wissenschaft.de

Die großen Fragen der Wissenschaft | Können wir ewig leben? Im Gespräch geht es um die tiefgreifenden biologischen Mechanismen hinter dem Altern, ethische Grenzen bei der Lebensverlängerung und um sinnvolle Strategien, länger gesund zu leben detektor.fm/wissen/die-g...

Können wir ewig leben, Björn Schumacher?

Alternsforscher Björn Schumacher über ewiges Leben, unseriöse Versprechen und Faktoren, die das Leben wirklich verlängern können.

detektor.fm

Hier der Podcast: mein Gespräch über »Altersuhren«, Fadenwürmer, den Traum von der ewigen Jugend und die richtige Medizin youtube.com/watch?v=Q6ey...

Können wir ewig leben, Björn Schumacher?

YouTube video by detektor.fm

youtube.com

Heute im @spektrum.de der Wissenschaft: mein Gespräch über »Altersuhren«, Fadenwürmer, den Traum von der ewigen Jugend und die richtige Medizin www.spektrum.de/news/longevi...

Die großen Fragen der Wissenschaft: Können wir ewig leben, Björn Schumacher?

Ein Gespräch mit dem Biologen Björn Schumacher über die Geheimnisse von Longevity – einem möglichst langen, gesunden Leben.

spektrum.de

Merry Christmas 🎄🎁 and happy new year 🎆🎈🎊 with all the best wishes for a great 2026

🚀 Now out in print: AGE DECELERATION AND REVERSAL GENE PATTERNS IN DAUER DIAPAUSE. How we can learn from nature of to slow aging and rejuvenate. Big congrats to Khrystyna Totska, João Barata, Walter Sandt, and @meyerdavid.bsky.social! @cecad.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

Age Deceleration and Reversal Gene Patterns in Dauer Diapause

The dauer diapause is a naturally occurring extraordinarily long-lived alternative C. elegans larval stage that, upon dauer exit, lives a normal adult life with full reproductive capacity. Here, we d...

onlinelibrary.wiley.com

This was a great start of the @erc.europa.eu Synergy funded @batprotect.bsky.social BATPROTECT workshop @cecad.bsky.social @unicologne.bsky.social in Cologne

BatProtect@batprotect.bsky.social · 8mo ago

BatProtect - 3 day programme kicked off by @bjornschumacher.bsky.social followed by keynote from #StevenAustad on Methuselah's Zoo: what nature can teach us about living longer, healthier lives

🔥🔥🔥Now out in print: how do germ cells instruct the soma and how does the soma impact inheritance? Together with Shoma Ishikawa we provide a comprehensive overview of The Somatic Impact on Inheritance and the Germline Control of the Soma - www.annualreviews.org/content/jour...

The Somatic Impact on Inheritance and the Germline Control of the Soma

The faithful transmission of genomic DNA over succeeding generations is an essential prerequisite for species maintenance. The germplasm theory by August Weismann has been foundational for the current...

annualreviews.org

It's a great pleasure to introduce the RACE ERA Chair Initiative for Establishing a Research and Innovation Program of Excellence on Ageing and Longevity at the University of Crete with @garinis.bsky.social

🧬🧬🧬Targeting Genome Stability to Mitigate Human Aging and Disease - read now our comprehensive review article written with Debbie Toiber how we can target the most fundamental mechanisms of aging and cancer. @annualreviews.bsky.social 🔗 go.shr.lc/3JohYMp

a computer generated image of a dna molecule with a dark background

ALT: a computer generated image of a dna molecule with a dark background

media.tenor.com

🚨Check out this new study from our Research Unit member @bjornschumacher.bsky.social on gene expression patterns linked to age deceleration and rejuvenation during Dauer Diapause. Congratulations! 🎉

Björn Schumacher@bjornschumacher.bsky.social · 10mo ago

🚀 🚀 🚀 Our latest paper is out now: Age Deceleration and Reversal Gene Patterns in Dauer Diapause. We can learn from nature how aging of a whole organism with completely differentiated tissues can be slowed and how that organism can be completely rejuvenated. onlinelibrary.wiley.com/doi/10.1111/...