The research is overwhelmingly clear: the daily lifestyle choices you make today dictate the health of your brain tomorrow. Are you actively building a resilient brain?
Dr. Dale Bredesen
@drdalebredesen.bsky.social
Dr. Dale Bredesen is the author of The Ageless Brain and The End of Alzheimer's, the Chief Science Officer of Apollo Health, and a pioneer in brain health research.
Health improvements in later life are more common than you think, and those who improve with age may tend to commit to the same habits. https://www.huffingtonpost.co.uk/entry/habits-health-improvement-ageing_uk_6ab3c3b0e4b08976697d1a05
Cognitive decline doesn't suddenly start at age 60; subtle changes can happen decades before a diagnosis is made. A comprehensive cognoscopy—like that provided by ReCODE and PreCODE—is vital in your 30s and 40s, long before memory symptoms surface.
High sugar intake—even from seemingly 'healthy' sources—significantly increases your risk of cognitive decline. That’s why KetoFLEX 12/3 is foundational to the ReCODE Protocol. Protect your brain by restoring metabolic flexibility. https://www.eatingwell.com/sugar-dementia-risk-study-12066701
Music has been well studied in dementia, and a fascinating new study highlights what caretakers know – even with Alzheimer's or Frontotemporal Dementia, listening to personal, favorite music sparks significant brain activity. https://medicalxpress.com/news/2026-09-brain-favorite-music-dementia.html
A HEPA air purifier may be one of the fastest and easiest ways to improve cognitive health. In a new study, cleaner indoor air improved cognitive performance by 12% (speed on executive function testing) after just one month! https://www.sciencedaily.com/releases/2026/08/260830000016.htm
A new study has found that binge-watching TV “very often” in midlife is associated with reduced brain volume. The damage can lead to dementia, stroke, cognitive decline, and more. https://www.healthline.com/health-news/binge-watching-tv-may-affect-brain-later
Want to increase strength? You may want to cultivate your microbiome first. Older adults with the bacterium Roseburia inulinivorans had 29% greater grip strength and better VO2, leg press, and bench press scores. https://www.sciencedaily.com/releases/2026/08/260820202904.htm
Bioidentical hormone replacement therapy is a popular topic for those on the ReCODE Protocol. In new research, estrogen hormone therapy use was linked to 39% lower odds of dementia and reduced biomarkers of Alzheimer’s. https://www.sciencedaily.com/releases/2026/08/260814011028.htm
One brisk 13-minute walk daily can protect your brain and can lower your risk of dementia by 72%. Results also showed that participants who took one long walk had a lower risk of dementia than their counterparts who broke up the exercise. https://www.nature.com/articles/s41398-026-04272-3
A new study shows compounds in coffee, particularly caffeic acid, activate a receptor that helps protect cells from stress, inflammation, and damage. Some other great sources of caffeic acid include turmeric, thyme, sage, and olive oil. https://www.sciencedaily.com/releases/2026/07/260719035927.htm
Medical acceptance, even for simple solutions, can take more than 30 years. Unfortunately, our brains can’t wait, but the good news is that there is now so much that can be done to prevent and reverse cognitive decline. Take the Cq: https://www.apollohealthco.com/know-your-cq/
My friend and colleague David Perlmutter has written a superb new book on microglia, the major immune cells of the brain. It is entitled Brain Defenders and I recommend it highly to all. Grab a copy at braindefenders.com now and you can claim some excellent preorder bonuses!
Join Dr. Dale Bredesen and Judy Benjamin this Thursday, August 13th, at 12:00 PM PT / 8:00 PM BST for a LIVE conversation with Judy about her incredible walk across the UK — from Land’s End to London. Register here: https://us02web.zoom.us/webinar/register/WN_QzFwtYG6TXaIXffkOHZENg
New research from the United Kingdom has found that cannabis use in older adults isn’t linked to faster cognitive decline or dementia. https://www.psypost.org/cannabis-use-in-older-adults-not-linked-to-faster-cognitive-decline-or-dementia/
A new study shows that KCL-286—a drug originally developed for spinal cord injury—repairs DNA damage and reduces brain inflammation in mice. This is a refreshing change from the normal laser focus on amyloid and tau proteins. https://www.sciencedaily.com/releases/2026/07/260711010118.htm
Researchers found that NFL players were four times more likely to die from neurodegenerative diseases than their non-athlete counterparts. https://www.espn.com/nfl/story/_/id/49317702/study-nfl-players-4-s-more-likely-die-neurodegenerative-disease
The World Health Organization updated its guidelines for reducing dementia risk and now recommends using multidomain interventions and avoiding air pollution, but they still don’t account for other major factors. https://www.medpagetoday.com/neurology/dementia/122266
Heart problems like coronary disease and heart failure have been linked to an increased risk of neurodegenerative diseases, but a new study indicates less severe events increase risk too. https://www.medicalnewstoday.com/articles/even-the-smallest-heart-issues-may-raise-dementia-risk-new-study-finds
New research shows that one large dose of psilocybin, also known as magic mushrooms, can alter your brain activity, brain structure, and even improve your mental health. https://www.medicalnewstoday.com/articles/one-dose-psilocybin-reshape-brain-activity-support-mental-health-study-neuroplasticity
New research has found that omega-3 fatty acids may not be as effective in the treatment of brain injuries and Alzheimer’s. https://www.discovermagazine.com/do-omega-3s-really-protect-the-brain-the-answer-may-depend-on-your-health-49067
A new study links accelerated biological aging and the global rise in early-onset cancers. I would be interested to see similar research into early-onset dementia. https://medicine.washu.edu/news/faster-aging-in-younger-generations-linked-to-rise-in-early-onset-cancer/
Join Drs. Dale Bredesen, Hans Frykman, & Chris Coward for a discussion on how BrainScan, Apollo Health's blood biomarker panel featuring high-sensitivity p-Tau 217, can detect cognitive decline earlier and support personalized care. https://us02web.zoom.us/webinar/register/WN_-VnlhEgORTela5fzBroxbw
The American Heart Association recently released a statement outlining 10 familiar factors that adversely affect brain health. https://www.medicalnewstoday.com/articles/brain-health-shaped-by-8-lifetime-mental-physical-environmental-and-lifestyle-factors
Workout warriors rejoice! New research shows that flexing your abs can help clean your brain. https://scitechdaily.com/this-simple-movement-could-be-secretly-cleaning-your-brain/
Congratulations to Dr. Ram Rao, Julie Gregory, and the whole team on the publication of a superb perspective on the KetoFLEX 12/3 diet and its remarkable impact on cognition. For anyone interested in why this nutritional approach works so well: https://www.mdpi.com/2072-6643/18/13/2206
New research from Florida Atlantic University found underlying mitochondrial disruptions that occur in both dementia and obesity, potentially explaining their connection. https://www.news-medical.net/news/20260505/Obesity-and-Alzheimere28099s-linked-through-early-metabolic-disruptions.aspx
In new research, nitrate-rich vegetables decreased dementia risk, while nitrates from processed meat or even drinking water increased it. Vegetables’ antioxidants may turn nitrate into beneficial nitric oxide, not N-nitrosamines. https://www.sciencedaily.com/releases/2026/06/260606075852.htm
increasing Sox9 protein levels in mice energized their aging astrocytes, preserving cognitive function and improving amyloid and tau clearance. Amyloid and tau plaques are symptoms not causes, but clearing them may still provide benefit. https://www.sciencedaily.com/releases/2026/05/260502013550.htm
A case study on psilocybin has made waves recently as a result of the impact it had on an 80-year-old Alzheimer’s patient. The paper describes miraculous recovery of bladder control, speech, and ambulation. https://medicalxpress.com/news/2026-06-high-dose-psilocybin-temporarily-lost.html