The first ever cover art from my lab! And an awesome story about how chromatin changes in response to the N/C ratio from my first grad student, Anusha Bhatt!

EMBO Reports@emboreports.org · 8mo ago

Have a look at the new issue: link.springer.com/journal/4431... The cover features work by Amanda Amodeao @aaamodeo.bsky.social and co-workers showing that local nuclear to cytoplasmic ratio regulates #histone H3.3 incorporation during zygotic #genome activation. link.springer.com/article/10.1...

Just a few days left to apply! If you do cool molecular/cell biology things and want to start a lab in a supportive department in New England please check out our ad.

Amanda Amodeo@aaamodeo.bsky.social · 12mo ago

My Department (Biology) at @dartmouthartsci.bsky.social is hiring this year! We have an opening for a Tenure Track Cell and/or Molecular biologist (broadly defined). Please share with your trainees/labmates/friends and reach out if you have questions. apply.interfolio.com/171625

My Department (Biology) at @dartmouthartsci.bsky.social is hiring this year! We have an opening for a Tenure Track Cell and/or Molecular biologist (broadly defined). Please share with your trainees/labmates/friends and reach out if you have questions. apply.interfolio.com/171625

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

My Department (Biology) at @dartmouthartsci.bsky.social is hiring this year! We have an opening for a Tenure Track Cell and/or Molecular biologist (broadly defined). Please share with your trainees/labmates/friends and reach out if you have questions. apply.interfolio.com/171625

Oh man, you guys. This is so important. Drosophila have led to so much in terms of what we understand about how genes work.

Lucas Waltzer @lucaswaltzer.bsky.social · last yr.

#drosophila @flybase.bsky.social request emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate! www.philanthropy.cam.ac.uk/give-to-camb...

Dartmouth at #Dros25

#Dros25 is off to a great start! If you're interested in zygotic genome activation & chromatin my lab has 2 great folks here: Anusha Bhatt has a talk on histone H3/H3.3 replacement in the chromatin session on Fri morning Grace Carey has a poster on N/C ratio sensing in ZGA on Sat afternoon

Stop the halt of NIH! I am reaching out to ask that you call your US Senators/Reps. Especially those of you in red states! Tell them how important the NIH is! www.senate.gov/senators/sen...

U.S. Senate: Contacting U.S. Senators

Please include your return postal mailing address when corresponding with a Senate office.

senate.gov

There are two weeks left to apply for the #ChooseDevelopment! Summer Undergraduate Research Program. Undergrads from underrepresented racial or ethnic group, first-generation college students, veterans & students with a disability are eligible. bit.ly/3FwHqYp Deadline: February 1, 2025 #devbio

My lab is looking to hire a research technician! Techs in my group run their own projects and participate fully in the scientific discussions in the lab (this is not a wash glassware, make media position). Ideal for someone looking to get a bit more research experience before applying for a PhD.

Our Institute for Biomolecular Targeting (bioMT) is looking for a *new core director* and protein purification specialist. If you're interested in working on a wide array of projects and living in the peaceful Upper Valley this is an excellent place to work. Links below. sites.dartmouth.edu/biomt/

First post on bsky. We've updated our preprint about the change in the histone H3 variant on chromatin during Zygotic Genome Activation. Thanks to new experiments by Anusha, it seems like our initial, simplistic idea that the embryo "ran out" of H3 was not right. www.biorxiv.org/content/10.1...

Local nuclear to cytoplasmic ratio regulates H3.3 incorporation via cell cycle state during zygotic genome activation

Early embryos often have unique chromatin states prior to zygotic genome activation (ZGA). In Drosophila, ZGA occurs after 13 reductive nuclear divisions during which the nuclear to cytoplasmic (N/C) ...

biorxiv.org