Marco P Abrate

@abrate.bsky.social

PhD in Neuroscience and AI at University College London

Excited to share that our preprint is out! doi.org/10.1101/2024... The structure of place cell reactivations was disordered in AD mice compared to WT! This was predictive of reduced place cell stability and memory performance on a radial-arm maze task. Here are a few details: 1/5🧵

Disordered Hippocampal Reactivations Predict Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is characterised by progressive memory decline associated with hippocampal degeneration. However, the specific physiological mechanisms underlying hippocampal dysfunction in A...

doi.org