Tessera

@acscardiology.bsky.social

Results of the FINEARTS-HF randomized clinical trial demonstrate that the PREDICT-HFpEF models performed well in terms of calibration and discrimination. Baseline risk did not modify the benefit of finerenone. jamanetwork.com/journals/jam...

Finerenone for Heart Failure and Risk Estimated by the PREDICT-HFpEF Model

This randomized clinical trial evaluated the effectiveness of finerenone in patients with heart failure and mildly reduced ejection fraction or preserved ejection fraction across the spectrum of risk ...

jamanetwork.com

@acscardiology.bsky.social · last yr.

There was no association between liberal fasting policies and witnessed aspiration. Further study of more liberal fasting policies is unlikely to find an association www.sciencedirect.com/science/arti...

No association between preprocedural fasting and witnessed pulmonary aspiration: A systematic review and meta-analysis

Preprocedural fasting has been a standard component of preoperative care since 1946 when an association between gastric volume and aspiration was made…

sciencedirect.com

@acscardiology.bsky.social · last yr.

Results of this cohort study suggest that the prevalence of CMP-PLP variants was substantial in patients with early-onset AF. Patients with AF carrying a CMP-PLP variant had an associated increased risk of future CMP/HF, independent of clinical and polygenic risk. jamanetwork.com/journals/jam...

Cardiomyopathy-Associated Gene Variants in Atrial Fibrillation

This cohort study investigates the prevalence and clinical implications of cardiomyopathy-associated pathogenic or likely pathogenic variants in patients with atrial fibrillation.

jamanetwork.com

@acscardiology.bsky.social · last yr.

Among persons with both chronic kidney disease and type 2 diabetes, initial therapy with finerenone plus empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either treatment alone. www.nejm.org/doi/full/10....

Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes | NEJM

Limited evidence exists to support the simultaneous initiation of sodium–glucose cotransporter-2 inhibitors and finerenone, a nonsteroidal mineralocorticoid receptor antagonist, in persons with chr...

nejm.org

@acscardiology.bsky.social · last yr.

High PCATRCA was independently associated with PoCE after PCI using current-generation DES. Combining PCATRCA with traditional cardiovascular risk factors and cCTA findings may enhance risk assessment for PoCE after PCI. eurointervention.pcronline.com/article/impa...

Impact of pericoronary adipose tissue attenuation on clinical outcomes after percutaneous coronary intervention

This study examined the association between coronary inflammation, measured by pericoronary adipose tissue attenuation, and clinical outcomes after percutaneous coronary intervention with drug-eluting...

eurointervention.pcronline.com

@acscardiology.bsky.social · last yr.

ATTR-specific treatment and AVR both result in significant survival benefit in dual pathology AS and ATTR-CA. Results should be interpreted in the context of the non-randomized study setting and differences in patient characteristics. academic.oup.com/eurheartj/ad...

Cardiac transthyretin amyloidosis treatment improves outcomes after aortic valve replacement for severe stenosis

AbstractBackground and Aims. Concomitant aortic stenosis (AS) and transthyretin-associated cardiac amyloidosis (ATTR-CA) is an increasingly recognized caus

academic.oup.com

@acscardiology.bsky.social · last yr.

Among older adults with high-risk or intermediate-risk PE, patients treated with CBT experienced lower mortality over the follow-up of up to 3 years, but higher risk of in-hospital bleeding complications www.jacc.org/doi/10.1016/...

Long-Term Outcomes Following Catheter-Based Therapies in Older Adults With Acute Pulmonary Embolism:

jacc.org

@acscardiology.bsky.social · last yr.

In stable patients with extensive noncalcified plaque volume at baseline, 18 months of evolocumab treatment was associated with a shift toward a lower risk quantitative plaque phenotype and reduction in microcalcification activity www.jacc.org/doi/10.1016/...

Effects of Evolocumab on Coronary Plaque Composition and Microcalcification Activity by Coronary PET and CT Angiography:

jacc.org

@acscardiology.bsky.social · last yr.

A significant burden of elevated Lp(a) was found in China, highlighting the necessity of prioritized Lp(a) screening in high-risk groups. Elevated Lp(a) was identified as a significant risk factor for site-specific subclinical atherosclerosis www.jacc.org/doi/10.1016/...

Prevalence of Elevated Lipoprotein(a) and its Association With Subclinical Atherosclerosis in 2.9 Million Chinese Adults:

jacc.org

@acscardiology.bsky.social · last yr.

n this prespecified analysis of a randomized clinical trial, patients with HFimpEF remained at high risk of CV events, underscoring the need for continued management despite LVEF improvement. jamanetwork.com/journals/jam...

Finerenone in Heart Failure With Improved Ejection Fraction

This prespecified analysis of a randomized trial examines profiles, risk, and response to finerenone among patients with hearth failure with improved ejection fraction compared with patients with left...

jamanetwork.com

@acscardiology.bsky.social · last yr.

Deferred stenting did not reduce all-cause mortality or the composite primary outcome after 10 years but reduced hospitalization for heart failure compared with conventional PCI. www.ahajournals.org/doi/full/10....

10-Year Outcomes of Deferred or Conventional Stent Implantation in Patients With STEMI (DANAMI-3-DEFER) | Circulation: Cardiovascular Interventions

BACKGROUND: Primary percutaneous coronary intervention (PCI) with stenting is recommended in ST-segment–elevation myocardial infarction. Immediate stenting may cause distal embolization, microvascular...

ahajournals.org

@acscardiology.bsky.social · last yr.

In ACS patients treated with DCS, a 1-month prasugrel-based DAPT strategy followed by prasugrel 5 mg monotherapy reduced NACE by 49%, mainly driven by a 77% reduction of bleeding events without compromising ischaemic safety eurointervention.pcronline.com/article/one-...

One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial

Find out more about this article on One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial

eurointervention.pcronline.com

@acscardiology.bsky.social · last yr.

The RV/LV diameter ratio offers real-time risk stratification and is a predictor of low cardiac index in patients with acute PE. www.sciencedirect.com/science/arti...

Real-time risk stratification in acute pulmonary embolism: the utility of RV/LV diameter ratio

This study evaluates the prognostic utility of the RV/LV diameter ratio in predicting low cardiac index (CI) in patients with acute intermediate-risk …

sciencedirect.com

@acscardiology.bsky.social · last yr.

Results reveal that long-term QOL and chest pain outcomes were the same with CT- vs ICA- guided first-test strategies at 3.5 years jamanetwork.com/journals/jam...

Health Status After CT or ICA for Stable Chest Pain

This secondary analysis of the Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) randomized clinical trial investigates if ...

jamanetwork.com

@acscardiology.bsky.social · last yr.

Effects of Evolocumab on Coronary Plaque Composition and Microcalcification Activity by Coronary PET and CT Angiography:

jacc.org

@acscardiology.bsky.social · last yr.

However, post-TAVR patients required greater fluoroscopic time (21.9 vs 17.7 mins, p<0.001) and had higher rates of post-procedural stroke (0.8% vs 0.4%, p=0.02) and bleeding (5.1% vs 2.9%, p<0.001). www.ajconline.org/article/S000...

Outcomes of Percutaneous Coronary Interventions Following Transcatheter Aortic Valve Replacement: Insights from the CathPCI Registry

Although transcatheter aortic valve replacement (TAVR) devices can impair coronary access, there are limited real-world data comparing outcomes of percutaneous coronary intervention (PCI) in post-TAVR...

ajconline.org

@acscardiology.bsky.social · last yr.

Contrast-derived indices have high specificity and negative predictive value, enabling rapid exclusion of microvascular dysfunction. This method is feasible, clinically useful and cost-saving compared with routine adenosine testing. www.ahajournals.org/doi/10.1161/...

American Heart Association Journals

ahajournals.org

@acscardiology.bsky.social · last yr.

Among patients with recent NSTEMI, a high baseline hsCRP level was associated with the presence of pan-coronary atherosclerosis and focal high-risk plaques www.jacc.org/doi/10.1016/...

Relationships of hsCRP to High-Risk Vulnerable Plaque After NSTEMI: Insights From the PROSPECT II Trial

jacc.org

@acscardiology.bsky.social · last yr.

Among statin-treated patients undergoing PCI, residual inflammation but not cholesterol risk was associated with an increased risk of MACE during follow-up. academic.oup.com/eurheartj/ad...

Residual cholesterol and inflammatory risk in statin-treated patients undergoing percutaneous coronary intervention†

AbstractBackground and Aims. Elevated LDL-cholesterol levels and inflammation, as assessed by high-sensitivity C-reactive protein, correlate with cardiovas

academic.oup.com

@acscardiology.bsky.social · last yr.

Exemplary effort by University Hospitals and Harrington Heart and Vascular Institute in Cleveland Ohio to reduce CV Mortality in a Rural Community in Ohio www.beckershospitalreview.com/cardiology/i...

Inside the multipronged effort to reduce CVD mortality at University Hospitals - Becker's Hospital Review | Healthcare News & Analysis

After making a $2.5 million investment in Cleveland-based University Hospitals Harrington Heart & Vascular Institute at the UH Portage Medical Center, which included establishing a catheterization lab...

beckershospitalreview.com

@acscardiology.bsky.social · last yr.

In patients with nonobstructive HCM, there was a reduction in myocardial T1 time with eplerenone, consistent with a reduction in diffuse myocardial fibrosis. www.jacc.org/doi/10.1016/...

The Antifibrotic Effects of Eplerenone in Hypertrophic Cardiomyopathy: A Randomized Clinical Trial

jacc.org

@acscardiology.bsky.social · last yr.

Interventional cardiologists experience significant stress, as measured by the LF/HF ratio, during complex, emergency, and complicated procedures; however, stress levels decrease later in the IC fellowship. www.doximity.com/newsfeed/c82...

doximity.com

@acscardiology.bsky.social · last yr.

Independent of the timing of statin initiation (i.e., whether for primary vs. secondary prevention of CVD), this study found an all-cause mortality benefit with statin therapy in patients on dialysis who had a very high risk for CVD or established CVD www.acc.org/Latest-in-Ca...

Statins in Patients on Dialysis: A Mortality Benefit? - American College of Cardiology

acc.org

@acscardiology.bsky.social · last yr.

Non-LAD CTO PCI significantly improved LVEF (8.2%) in HFrEF patients over two years, regardless of pre-procedure viability testing or post-procedural medical therapy. www.doximity.com/newsfeed/186...

Impact of Chronic Total Occlusion PCI in Non-LAD Coronary Arteries on Patients with Cardiomyopathy

: To evaluate the impact of left circumflex artery (LCX) or right coronary artery (RCA) chronic total occlusion percutaneous coronary intervention (CTO PCI) on left ventricular ejection fraction (LVEF...

doximity.com

@acscardiology.bsky.social · last yr.

Individuals who are genetically predisposed to developing CAD also face an increased risk of developing dementia in old age. This risk is reduced in those demonstrating healthy lifestyle profiles earlier in the lifespan www.ahajournals.org/doi/full/10....

Genetic and Lifestyle Risks for Coronary Artery Disease and Long-Term Risk of Incident Dementia Subtypes | Circulation

BACKGROUND: Shared genetic and lifestyle risk factors may underlie the development of both coronary artery disease (CAD) and dementia. We examined whether an increased genetic risk for CAD is associat...

ahajournals.org