🤰 What does MASLD mean for pregnancy? The Fatty Liver in Pregnancy (FLIP) study evaluated 1,100+ women, finding 87% with steatosis on imaging met MASLD criteria and identifying novel links with adverse maternal & neonatal outcomes. 🔬 @tatyanakushner 🔗: https://ow.ly/1pjA5101IjZ

🍂 The November issue of CGH is now available! Featured articles: 🔸A study on heavy drinking and Implications for SLD 🔸Research on the Long-Term Effectiveness of Dupilumab in EoE 🔸The influence of SLD and subtypes on pregnancy and neonatal outcomes. 🔗: https://ow.ly/wvpe5100xeO

Microscopic Colitis is on the rise in 🇸🇪. Prevalence: 170/100k (2021). Lifetime risk: 1/54 women, 1/133 men. MC incidence outpaced normal mucosa, suggesting more biopsies alone don’t explain the increase. 🔗: https://ow.ly/VirJ50ZXL1q

💊Long-term data from 6 UC & Crohn’s disease trials show upadacitinib was generally well tolerated, with findings supporting its favorable safety profile and treatment decisions for patients with IBD. 🔗: https://ow.ly/VPKU50ZVruv

⏱️ Could earlier treatment make a difference in ulcerative colitis? Starting biologic therapy within 1 year of diagnosis was associated with a lower risk of structural disease progression, supporting earlier treatment. 🩺🔬 🔗: https://ow.ly/ERx850ZVrfc

📣The THCC-RI accurately stratifies patients with #cirrhosis by their future risk of HCC, offering a powerful tool to guide precision surveillance and early detection. 🔗: https://ow.ly/jYcm50ZTctp

#MASLD patients with high cardiovascular risk have more severe #liverfibrosis and higher risk of liver complications, highlighting the need for integrated cardiometabolic and hepatic care. 🔗: https://ow.ly/13B050ZTbXX

💫 #MetALD affects women differently. From greater alcohol sensitivity to menopause-related risk and transplant disparities, this review synthesizes evidence on sex-specific biology, outcomes, and care gaps in women with MetALD. 🔗: https://ow.ly/3OKR50ZTbQL

📖 The October issue of CGH is now online! It features: 🟢A Narrative review on metabolic dysfunction and alcohol-associated steatotic liver disease in women. 🟢Risk Stratification of a Novel Noninvasive Fibrosis Score in MASLD 🟢And much more! 🔗: https://ow.ly/vqnF50ZQznw

⏰Not too late to explore the September issue! If you haven't checked it out yet, don't miss: 🟧Research on IBD and functional dyspepsia in night shift workers 🟧 A systematic review of steroid therapies for eosinophilic esophagitis 🟧 And much more! 🔗: https://ow.ly/YgmU50ZOlMx

This #PeerReviewWeek 💫 CGH recognizes Dr. Joan Genescà as one of our top reviewers! His dedication to peer review has helped ensure scientific quality while advancing clinical practice and medical knowledge. Thank you Dr. Genescà!

🩺📈 In a large #MASLD cohort, 1-year changes in liver stiffness predicted long-term liver-related events and decompensation, while CAP, ALT, and FIB-4 changes did not. Early LSM changes may be a strong marker of long-term prognosis. 🔗 https://ow.ly/pgTe50ZLeJw

📣Maintaining or improving healthy behaviors during early adulthood was associated with a reduction risk of midlife steatotic liver disease, regardless of genetic background. 🔗: https://ow.ly/AmGh50ZLezJ

🧪🌍 In 18,759 MASLD patients across 41 countries, noninvasive tests showed good accuracy but varied by age, T2D, and obesity. Agile-3+ remained consistently reliable, supporting more personalized risk stratification and testing strategies. 📊 🔗: https://ow.ly/BbPw50ZLept

💫 In a Veterans cohort, alcohol use disorder increased HCC risk primarily through active hepatitis C infection. Direct-acting antivirals reduced, but did not eliminate, this risk, underscoring the need for multidisciplinary AUD care. 🔗: https://ow.ly/lYHA50ZJ017

📖 In this study on EUS-PPG, we established expert agreement on best practices, technique and future research practices using the modified Delphi process, with total 53 consensus statements after 2 rounds of voting. 🔗: https://ow.ly/WZHS50ZGej7 @ThomasJWangMD

INTELCAPE: a deep learning system that automates Crohn’s disease diagnosis via capsule endoscopy. It boosts clinician accuracy by 18.2 percentage points and cuts reading time by 65.7%, especially aiding less-experienced doctors. Read more here: https://ow.ly/qSOj50ZGeeT

📖 The September issue is now online! It features: 🔷 Research on IBD and functional dyspepsia in night shift workers 🔷 A systematic review of steroid therapies for eosinophilic esophagitis 🔷 A noninvasive AI technique for diagnosing Crohn’s disease 🔗 https://ow.ly/eTI850ZEOki

🩺 Should all elderly patients with uncomplicated bile duct stones undergo ERCP? This study found early ERCP was not associated with better outcomes and may increase adverse events. Findings support a selective, “as-needed” approach. 📊 🔗:https://ow.ly/xAvE50ZAZJ8

✨Less sugar early in life may have lasting benefits. This study found a 30% lower risk of adult #MASLD and related liver complications 🩺, with over 60% of the protective effect mediated by improved metabolic traits 🔗: https://ow.ly/hCto50ZAWHg

🩺 JAK inhibitors are effective and safe rescue therapies for ASUC across short-, intermediate-, and long-term follow-up. Tofacitinib and Upadacitinib showed similar outcomes. 📊💊 @DrAnuraagJ @ibdseb @drvishal82 🔗: https://ow.ly/EVMe50ZyWya

💫 The newest issue of CGH is here! Check out this featured article ➡️ "Artificial Intelligence Tools for Gastrointestinal Research: A Practical Guide" 🔗: https://ow.ly/Jfzt50ZtRRh

🩺 New research shows that integrating the aMAP score with liver stiffness measurements significantly improves prediction of hepatocellular carcinoma (HCC) risk in patients with chronic hepatitis B receiving antiviral therapy. 🔗: https://ow.ly/MVtN50ZojoG

🧠 New in CGH! Diary-based data reveal fecal incontinence is more than urge vs passive. 💩📊 Four distinct phenotypes link stool patterns, anorectal function, and quality of life—supporting a more personalized approach to care. 🔗: https://ow.ly/a5Qt50ZlFvU

"Among patients with #cirrhosis, discrimination and mistrust are common, especially for Black patients. Tackling these barriers is essential for equitable liver care." X: @nicole_rich8; @docamitgs; @kanwalfasiha" 🔗: https://ow.ly/GoQf50ZlETG

🔬🩺 Sessile serrated lesions are key #CRC precursors but are often missed. In a multicenter randomized tandem trial, NBI significantly lowered miss rates for SSLs, proximal serrated lesions, and adenomas. 🎯 🔗: https://ow.ly/ZLP250ZlEIL

🌍🩺 #IBD is a global disease. In a systematic review of population-based studies including 1+ million patients, researchers found largely similar IBD phenotypes across ethnicities and regions, with notable differences observed in #Crohnsdisease. 🔬 🔗:https://ow.ly/l61V50ZlEv8

🩺 Early #livertransplant referral can be life-saving. This expert guidance helps providers recognize when patients with decompensated cirrhosis may benefit from transplant evaluation and specialized care. 🫀#CGH 🔗: https://ow.ly/ynrG50ZlCUo

🚨 ICYMI: The July issue of #CGH is now online! 🟧 Research on narrow-band imaging and sessile serrated lesion miss rates 🟧 A review offering guidance for timely liver transplantation referral 🟧 A systematic review of IBD phenotypes across race, ethnicity, and geography 🔗: https://ow.ly/EJ0350ZjJ2I

Can liver stiffness changes predict outcomes? 📊 This meta-analysis shows dynamic LSM shifts matter—↑ risk in progressors, ↓ risk in regressors ✅ Serial LSM could help monitor chronic liver disease & guide trials. 🧬 #LiverDisease #Hepatology 🔗: https://ow.ly/6UUl50ZepbB