The Age of Aging

@ageofaging.bsky.social

A podcast about living well with an aging brain, released every other Tuesday. Hear a wide range of stories from aging experts to patients and caregivers. Listen to The Age of Aging on Spotify, Apple Podcasts, or wherever you get your podcasts.

Dogs are more than companions. For many older adults, they are motivators to keep moving, steady sources of comfort, and even partners in dementia care. Our latest episode celebrates this bond, with stories from caregivers and expert insights into why humans and dogs just get each other.

Canine Care: Can A Dog Help You Live Well Longer?

At the Penn Memory Center, we often recommend exercise, social engagement, and a solid support system to help people age well. Owning a dog is not on that list, but maybe it should be. For many older adults, dogs are more than companions. They’re motivators to stay active, reasons to connect with neighbors, and steady sources of comfort through life’s challenges. Emerging research suggests that that this age-old bond between humans and dogs may be one of our healthiest friendships. On this episode of The Age of Aging, we celebrate dogs, and how they might help us live long, healthy lives.   First, we hear from caregivers and dog owners about how their dogs help them care for their loved ones with dementia. Then, Professor Philip Tedeschi explains how humans’ co-evolution with dogs has made us perfect support system for one another. Lynn Cronomiz recounts how a powerful moment between a therapy dog and her mother with Alzheimer’s helped her process her mother’s passing. Finally, we explore humans’ inseparable connection with nature through the biophilia hypothesis.  Resources  • Dog ownership (https://ebusiness.avma.org/files/ProductDownloads/eco-pet-demographic-report-22-low-res.pdf) in the U.S. statistics – American Veterinary Medical Association  • “2025 Alzheimer’s Facts and Figures” (https://www.alz.org/getmedia/ef8f48f9-ad36-48ea-87f9-b74034635c1e/alzheimers-facts-and-figures.pdf) –  Alzheimer’s Association  • Listen to Season 1 Episode 4, “Diagnosing Dementia,” (https://podcasts.apple.com/us/podcast/diagnosing-dementia/id1757439424?i=1000668135282) featuring Lynn Cronomiz  • Learn more about the Insitute for Human-Animal Connection (https://socialwork.du.edu/humananimalconnection)   • Visit KPETS, (https://kpets.org/) which Lynn Cronomiz does her therapy dog work with  • Learn more about the “biophilia hypothesis” (https://www.britannica.com/science/biophilia-hypothesis)   • Petfinder (https://www.petfinder.com/) to adopt a pet near you  • Visit the American Kennel Club website (https://www.akc.org/) for more information on dog breeds  Special thanks to Tom Casey, Miguel Centeno, Kathy Oldfield, Philip Tedeschi LCSW, MSSW, Lynn Cronomiz, and Carlo Siracusa DVM, PhD, DACVB, DECAWBM  The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and Penn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharpe.  The Age of Aging is made possible by generous support from the Michael Naidoff Communications Hub fund and our sponsor, the TIAA Institute. The TIAA Institute is a think tank committed to building knowledge that advances lifelong financial security and well-being while considering the intersections of health and wealth. Their cutting-edge research provides actionable financial and longevity insights that help individuals and employers navigate the complex journey of aging.

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“The POINTER study shows lifestyle choices like exercise, diet, and social connection can boost brain health.” – Dr. Jason Karlawish Hear more takeaways from AAIC 2025 in our bonus Age of Aging episode. ▶️ Watch the full episode ✅ Subscribe today so you don’t miss Season 4 coming soon

This Moment in Alzheimer's: Taking Stock and Look Forward

Welcome to a mid-year bonus episode of The Age of Aging! While the podcast takes a short break between seasons, we wanted to bring you a special update on the state of Alzheimer’s today. Penn Memory Center Co-Directors Dr. Jason Karlawish and Dr. David Wolk sat down with Terrence Casey to share their reflections from this year’s Alzheimer’s Association International Conference (AAIC), which they attended earlier this summer. They discuss their biggest takeaways, including the impact of NIH funding cuts, the rapid innovations that continue to shape the field, and what they’re keeping their eye on for next year’s conference in London.   We hope you enjoy and stay tuned for season 4 of The Age of Aging this fall! If you enjoy the show, leave us a review and share this episode with a friend. If you have any story suggestions for Season 4 and beyond, contact us at ageofaging@pennmedicine.upenn.edu (mailto:ageofaging@pennmedicine.upenn.edu) .   Resources  • Learn more about the Alzheimer’s Association and AAIC (https://aaic.alz.org/overview.asp)   Special thanks to Jason Karlawish, MD and David Wolk, MD.  The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.

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What will shape Alzheimer’s research in the year ahead? In a bonus episode of The Age of Aging, Penn Memory Center’s Dr. Jason Karlawish & Dr. David Wolk share insights from AAIC 2025 on funding, biomarkers, & breakthroughs already changing care.

This Moment in Alzheimer's: Taking Stock and Look Forward

Welcome to a mid-year bonus episode of The Age of Aging! While the podcast takes a short break between seasons, we wanted to bring you a special update on the state of Alzheimer’s today. Penn Memory Center Co-Directors Dr. Jason Karlawish and Dr. David Wolk sat down with Terrence Casey to share their reflections from this year’s Alzheimer’s Association International Conference (AAIC), which they attended earlier this summer. They discuss their biggest takeaways, including the impact of NIH funding cuts, the rapid innovations that continue to shape the field, and what they’re keeping their eye on for next year’s conference in London.   We hope you enjoy and stay tuned for season 4 of The Age of Aging this fall! If you enjoy the show, leave us a review and share this episode with a friend. If you have any story suggestions for Season 4 and beyond, contact us at ageofaging@pennmedicine.upenn.edu (mailto:ageofaging@pennmedicine.upenn.edu) .   Resources  • Learn more about the Alzheimer’s Association and AAIC (https://aaic.alz.org/overview.asp)   Special thanks to Jason Karlawish, MD and David Wolk, MD.  The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.

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Season 3 of The Age of Aging was our most personal season yet. We talked about caregiving at every age, memory and meaning, creativity and connection, and the future of dementia care. Take a look back in this short video recap and get ready for a brand new season this fall.

“I tried to be strong. I thought I could do it alone. I broke.” In the season finale of the Age of Aging, caregiver Linda Szypula reflects on the emotional toll of caring for a loved one with Lewy Body Dementia, and the power of letting others in. 🎧 Listen now: bit.ly/4eY8L8K

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Lewy Body Disease is the second most common cause of dementia, yet it’s often misdiagnosed and misunderstood. In our Season 3 finale, we spotlight this complex condition through film, caregiving stories, and expert insights from Penn Memory Center Co-Director Dr. Jason Karlawish. 🎧 bit.ly/4eY8L8K

Season 3 Finale: Neither Superheroes, Nor Angels

When we talk about dementia on this podcast, we are often talking about its most common cause: Alzheimer's disease. However, dementia has many causes, and among the most prevalent after Alzheimer’s is Lewy Body Disease. Though it can share similarities with Alzheimer’s, Lewy Body Dementia (LBD) has distinct symptoms and challenges that can complicate diagnosis, treatment, and caregiving.   On the season 3 finale of the Age of Aging, we explore Lewy Body Disease and its impact on caregivers and families.   We begin with a clip from the documentary Facing the Wind, which follows two caregivers as they navigate caring for their husbands with Lewy Body Disease. Then, Co-Host Terrence Casey shares his reflections on a live Q&A following a screening of the film in Philadelphia. Finally, Dr. Jason Karlawish provides a deeper insight into Lewy Body Disease, its significance in the world of aging research, and what it reveals about caregiving today.  Resources  • Find an upcoming screening (https://facingthewindfilm.com/screenings/) of Facing the Wind  • Learn more about Lewy Body Dementia (https://pennmemorycenter.org/education-and-support-resources/understanding-my-diagnosis/ed-lewy-body-dementia-parkinsons-dementia/)   • National Institute of Health booklet (https://www.lbda.org/wp-content/uploads/2021/03/lewy-body-dementia-booklet.pdf) on Lewy Body Dementia  • More resources on Lewy Body Dementia Association (https://www.lbda.org/) website  Special thanks to Tony Heriza, Deirdra Fishel, and Linda Szypula for sharing their film with us and being a part of this episode. Special thanks as well to ARTZ Philidelphia for presenting the screening and Q&A. The Age of Aging is a Penn Memory Center production hosted by Editorial Director Terrence Casey and Producer Jake Johnson, in partnership with the Penn FTD Center, the Penn Institute on Aging, and UPenn’s Alzheimer’s Disease Research Center. Contributors include Nicolette Calcavecchia, Dalia Elsaid, Jason Karlawish, Emily Largent, and Meaghan Sharp.

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What happens to intimacy when dementia enters a relationship? In the latest Age of Aging episode, Penn Memory Center Director of Social Work Alison Lynn opens up a quiet but common part of caregiving—and gives families permission to talk about it. 🎧 Listen now: bit.ly/3IlJ1Hb

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💬 “I felt like his wife again—not his caregiver.” In our most vulnerable episode yet, caregiver and author Lisa Marshall opens up about love, grief, and the moment she chose to say goodbye to physical intimacy—with tenderness and intention. Listen now: bit.ly/3IlJ1Hb

“We need to move in the direction of oncology. Early detection matters.” Dr. Kyra O’Brien joined The Age of Aging to talk anti-amyloid therapies, new blood tests for Alzheimer’s, and why the GUIDE program could transform care for both patients and caregivers. 🎧 Listen now: bit.ly/408tb9d

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As Chief Medical Officer at Penn Medicine, Dr. PJ Brennan helped lead the health system through the COVID-19 crisis. In our latest episode, he reflects on what the pandemic revealed about how we care for older adults—and where we go from here. 🎧 Listen to the full episode: bit.ly/408tb9d

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“The story started with love.” After early-onset dementia changed their families, Diana Cose and Patty LaFleur built Lorenzo's House—a lifeline for young caregivers. From peer matches to youth support groups, they’re reshaping dementia care. 🎧 Listen now: bit.ly/3Zr2VGC

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At 8, Sierra’s dad was diagnosed with dementia. At 16, she’s stepping into caregiving—and advocacy. In the latest Age of Aging episode, Sierra shares what it’s like to grow up while helping a parent forget less and live more. 🎧 Hear her story on the latest Age of Aging episode: bit.ly/3Zr2VGC

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What is something in your home that you treasure? In our latest episode, hosts Jake and Terrence reflect on objects that hold deep meaning, from a champagne cork to a mother’s handwritten diaries. 💬 What’s your answer? 📞 Call 571-449-6474 and leave a voicemail to be featured in a future episode.

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“I had to choose—stay home and care for my mom, or take a scholarship to Brown.” Paige’s story is one of grief, courage, and caregiving at 21. Hear how early-onset dementia changed everything—and how support from Lorenzo's House helped her find purpose. Listen here: bit.ly/3Zr2VGC

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“Mindset doesn’t just live in the brain—it shapes the brain.” – Dr. Jason Karlawish, Penn Memory Cente Co-Director In our latest episode, Dr. Karlawish and AARP’s Debra Whitman explore how changing the way we think about aging can change everything. Listen now: bit.ly/3Z29HlU

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“Change your mindset about aging—and you could gain 7 years of life.”– Debra Whitman, Chief Public Policy Officer, AARP In our newest episode, Debra joins PMC Co-Director Dr. Jason Karlawish to talk about longevity and rethinking what it means to grow older. 🎧 Tune in now: bit.ly/3Z29HlU

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What’s something that makes you laugh? We’re collecting real answers to a Beautiful Question from our latest episode. 📞 Call (571) 449-6474 Tell us your name, where you’re calling from, and what cracks you up. Your answer might be featured in a future episode!

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