I am looking for PhD students and postdocs to join my lab at the University of Pittsburgh in Fall 2027. Anyone excited about urban evolution, hummingbirds, & community engagement, please reach out! And/or find me at #AOS2026 this week! More info here: www.valentina-alaasam.com

Full-length single-cell spatial transcriptomics reveals spatial and cell-type-specific transcript isoforms in the primate brain www.nature.com/articles/s41...

Full-length single-cell spatial transcriptomics reveals spatial and cell-type-specific transcript isoforms in the primate brain - Nature Methods

Fullscope-seq combines a spatial transcriptomics approach (Stereo-seq) with long-read sequencing. The approach provides isoform information at single-cell resolution across a large field of view, as d...

nature.com

Amazing to see this online today! A very fun project over the past couple of years (made all the better by a great team of people to work with!)

Yulin Zhang@yulinzhang.bsky.social · 6d ago

Good news! Our paper (with @aabiddanda.github.io @sarahaj34.bsky.social @codushlaine.bsky.social and Priya Moorjani) is now officially online! www.science.org/doi/10.1126/...

Happy to see this project from the twilight months of my PhD out: authors.elsevier.com/c/1nWChgeXHnOF

Rajiv McCoy@rajivmccoy.bsky.social · last wk.

In this collaboration with the Gokcumen lab, @alberaqil.bsky.social developed a method based on interchromosomal linkage disequilibrium to detect false positive trans-eQTLs, showcased on GTEx and MAGE. The approach could be used to filter other trans molecular QTLs, which may be similarly impacted.

🧬 New from Aqil et al! 📄 Mismapping of sequencing reads from polymorphic duplications generates spurious trans-eQTLs

Mismapping of sequencing reads from polymorphic duplications generates spurious trans-eQTLs

Polymorphic gene duplications absent from the reference genome can generate spurious trans-eQTLs. Specifically, variants tagging the polymorphic duplicate may masquerade as trans-eQTLs regulating the ...

cell.com