Albert Vilella, PhD.
@albertvilella.bsky.social
Bioinformatics Scientist / Next Generation Sequencing, Single Cell and Spatial Biology, Next Generation Proteomics, Liquid Biopsy, SynBio, AI/ML in biotech // http://albertvilella.substack.com
Elon Musk is yet again giving wild predictions of what his companies are going to be achieving in a few years time, but this time isn't affecting what brand the robotaxi will be, Waymo or Tesla, but rather predicting the future of medicine, or to be more precise, surgery.
This is truly a reshuffle... They must have lots of ideas they want to pursue outside the Deepmind remit
*have ?
This is truly a reshuffle... They must hate lots of ideas they want to pursue outside the Deepmind remit
Via @aixbiobot.bsky.social A Structural Antibody Benchmark of AlphaFold3 reveals Hallucinated Epitopes and a Bias for Orderness www.biorxiv.org/content/10.6...
A Structural Antibody Benchmark of AlphaFold3 reveals Hallucinated Epitopes and a Bias for Orderness
AlphaFold3 has shown promise as a tool for predicting antibody-antigen binding, yet its performance across large datasets has not been fully characterized. In this study, 3401 experimentally validated...
biorxiv.org
Illumina $ILMN Q2 2026 results: 83% of the Gigabases for 59% of the Dollars, and the Axelios threat open.substack.com/pub/albertvi...
Illumina Q2 2026 results: 83% of the Gigabases for 59% of the Dollars, and the Axelios threat
This is the best reported quarter Illumina has printed in three years, and almost none of it came from the line that is supposed to carry the story.
open.substack.com
I did not have this in my bingo card this year: "DeepMind dismantles AlphaFold team in strategy shift" #Alphafold #AI #Biotech #DeepMind
One of the companies I track in my Substack will begin trading in the stock market today: Freenome $FRNM
Are we there yet? Biotech stock and VC funds recovering from a long desert crossing period. What would happen if the AI bubble were to burst tomorrow? open.substack.com/pub/albertvi...
Are we there yet? Biotech stock and VC funds recovering from a long desert crossing period
What would happen if the AI bubble were to burst tomorrow?
open.substack.com
Tempus AI $TEM agrees to acquire Personalis $PSNL for $1.5B And what it means for Cancer Diagnostics, Liquid Biopsy and Early Cancer Screening open.substack.com/pub/albertvi...
Tempus AI agrees to acquire Personalis for $1.5B
And what it means for Cancer Diagnostics, Liquid Biopsy and Early Cancer Screening
open.substack.com
UniFlow: Unifying protein conformational ensemble generation and machine-learned force fields with a scalable normalizing Flow www.biorxiv.org/content/10.6...
UniFlow: Unifying protein conformational ensemble generation and machine-learned force fields with a scalable normalizing Flow
Molecular dynamics (MD) provides a principled method for modeling equilibrium protein conformational energy landscapes, but its computational cost limits access to long timescales and larger protein s...
biorxiv.org
About 14.6% of #Bioinformatics #Scientists and #Computational #Biologists now have a @bsky.app account. My estimates is that there are about: 13,000 Bioinformatics Scientists with an active social media profile, and round 2,300 Computational Biologists, out of which around 14.6-14.7% have Bluesky.
Albert Vilella, PhD.@albertvilella.bsky.social · 3w agoI ran it again searching with a limit of 100,000 and got: AccountType frequency ------------- --------- Personal 1886 Institutional 473
Element Bio @elembio.bsky.social wins a court battle against @illumina in Germany, and what it means for the #NGS and #Multiomics fields moving forward open.substack.com/pub/albertvi...
Element Bio succeeds in German court battle against Illumina over MiSeq and MiSeqDx instruments
And what it means for the NGS and Multiomics segment moving forward
open.substack.com
I am doing more investigating on the uptake of @bsky.app by the #Bioinformatics and #ComputationalBiology community. I found 2114 accounts where the Bio contains the words "Bioinformatics" or "Computational Biology", out of which the large majority are personal but there are some institutional ones.
Are we moving into a new world where #Multiomics and #AI can help develop diagnostic tests in a fraction of the time than before? open.substack.com/pub/albertvi...
Sera Prognostics Company Profile
Are we moving into a new world where Multiomics and AI can help develop diagnostics tests at a fraction of the time than before?
open.substack.com
Remarkable progress in cardiovascular disease
Freenome has updated the performance metrics for the v2 of their SimpleScreen #CRC assay. But what does it mean for the field of #LiquidBiopsy #NGS #CancerDx ? open.substack.com/pub/albertvi...
Freenome's updated sensitivity values for their SimpleScreen CRC assay
Updated test version achieved significant performance improvement in detecting advanced precancerous lesions, including those with high-grade dysplasia
open.substack.com
Concentration of the Nifty Fifty over the different decades
#NGS and #Multiomics news 9th July 2026 including @alignedbio new nanowire-based sequencing system to turn Illumina SBS into a single-molecule method. open.substack.com/pub/albertvi...
NGSX News 9th of July 2026
Aligned Bio new Nanowire Sequencing Technology, and other pieces of NGS and Multiomics news around the world
open.substack.com
Moleculent, Stellaromics, and others enter the Spatial and Cell Biology #biotech segment open.substack.com/pub/albertvi...
More companies enter the Spatial Biology and Cell Biology Biotech segment
The landscape of the Spatial Biology and Cell Biology Biotechnology sectors is undergoing a paradigm shift, moving from early-stage, standalone hardware platforms to an ecosystem of platforms offering...
open.substack.com
An assortment of #NGS and #Multiomics news, both basic and #Applied in #CancerDx and other fields albertvilella.substack.com/p/ngsx-news-...
Caris Detect enters the MCED space What does it mean for the other players in Early Cancer Detection, like Grail, Guardant Health, Exact/Abbott, Freenome and others open.substack.com/pub/albertvi...
Caris Detect enters the MCED space
What does it mean for the other players in Early Cancer Detection, like Grail, Guardant Health, Exact/Abbott, Freenome and others
open.substack.com
On July 1, Bloomberg reported Meta’s plans for a cloud business. The plan involves standing up a new division to sell surplus AI compute capacity externally, with monetization coming through two routes: selling access to Meta’s Muse Spark models (a structure similar to AWS Bedrock),
