And that's a wrap on the #GermanConferenceonBioinformatics 2026! We were happy to gather the international bioinformatics community at SIC on the 40th anniversary of GCB and the 25th anniversary of the Center for Bioinformatics at @uni-saarland.de. See you next year at @unituebingen.bsky.social! 👋

I am delighted to share with you the newest update for our webserver: tools.helmholtz-hips.de/structman - Inclusion of the AlphaFold DB predicted complexes - PDB IDs support - We added some new residue-level features - and more (check out the link)

🧬🖥️ Call for Posters! Join us in celebrating 40 years of the German Conference on #Bioinformatics (#GCB2026) 🎉 📍 Saarbrücken | 🗓 22–25 Sep 2026 Submit your research & shape the future of Bioinformatics! Deadline Poster: 6 Aug 2026 👉 gcb2026.de

We are excited to announce the Call for Abstracts for the first "Structure of Biological Molecules" Workshop taking place at the 40th German Conference for Bioinformatics (GCB) on September 22, 2026 in Saarbruecken. We depend on your contributions! old-shatterhand.github.io/workshop_sbm...

Bioinformatiker Andreas Keller der Saar-Universität erhält neun Millionen Dollar für die internationale Parkinsonforschung. Ziel seiner Forschung ist es, Wirkstoffe zu finden, die bei der Behandlung der Parkinson-Krankheit helfen können. 👉 www.uni-saarland.de/aktuell/bioi... © Oliver Dietze/HIPS

Bioinformatiker Andreas Keller erhält neun Millionen Dollar für internationale Parkinsonforschung

Professor Andreas Keller und sein Team von der Universität des Saarlandes wurden ausgewählt, dem Kooperationsnetzwerk (CRN) beizutreten. Damit verbunden ist eine Förderung durch die Initiative „Aligni...

uni-saarland.de

In the first few days after the update, our users unwillingly uncovered some bugs that slipped through our internal testing schemes. Everything that led to crashes in the last week is fixed now.

Alexander Gress@alexandergress.bsky.social · 5mo ago

I am delighted to announce our newest update of our tools.helmholtz-hips.de/structman/ webserver. Highlights of the newest update: - Inclusion of the AlphaFold DB collaboration datasets - Addition of MSAs to StructMAn outputs - Addition of predicted complex structures

I am delighted to announce our newest update of our tools.helmholtz-hips.de/structman/ webserver. Highlights of the newest update: - Inclusion of the AlphaFold DB collaboration datasets - Addition of MSAs to StructMAn outputs - Addition of predicted complex structures

Information Leakage in Enzyme Substrate Prediction https://www.biorxiv.org/content/10.64898/2026.02.26.708291v1

We are happy to present a piece of analysis that I consider to have a major impact on our understanding of how good variant effect prediction (VEP) tools really are: www.biorxiv.org/content/10.6....

🧬🖥️ Call for Abstracts OPEN! Join us in celebrating 40 years of the German Conference on #Bioinformatics (#GCB2026) 🎉 📍 Saarbrücken | 🗓 22–25 Sep 2026 Submit your research & shape the future of Bioinformatics! Deadlines Workshops: 31 Mar 26 Talks: 3 May 26 Poster: 6 Aug 26 👉 GCB2026.DE

StructGuy: Data leakage free prediction of functional effects of genetic variants. https://www.biorxiv.org/content/10.64898/2025.12.01.691563v1

We are excited that our paper "Cleanifier: Contamination removal from microbial sequences using spaced seeds of a human pangenome index" is now published at Bioinformatics (doi.org/10.1093/bioi...). You can find it at gitlab (gitlab.com/rahmannlab/c...) or install it via PyPI or Bioconda.

Cleanifier: Contamination removal from microbial sequences using spaced seeds of a human pangenome index

AbstractMotivation. The first step when working with DNA data of human-derived microbiomes is to remove human contamination for two reasons. First, many co

doi.org

Detection of alternative splicing: deep sequencing or deep learning? https://www.biorxiv.org/content/10.1101/2025.08.23.671909v1

SingleRust: A High-Performance Toolkit for Single-Cell Data Analysis at Scale https://www.biorxiv.org/content/10.1101/2025.08.04.668429v1

Our preprint is finally out for SingleRust: doi.org/10.1101/2025... Stay tuned: @singlerust.bsky.social, @ianfd.bsky.social github.com/SingleRust

SingleRust: A High-Performance Toolkit for Single-Cell Data Analysis at Scale

Single-cell RNA sequencing studies increasingly generate datasets exceeding 10 million cells, surpassing the memory capacity of standard analytical tools on typical institutional infrastructure. Here ...

doi.org

Matthias Flotho@mflot.bsky.social · last yr.

Check out today at #ISMBECCB2025 A92 Ians (@ianfd.bsky.social) awesome poster about #SingleRust. Scalable and memory efficient single cell processing! Stay tuned: @singlerust.bsky.social github.com/SingleRust

What an exciting week it's been at the #ISMBECCB2025 conference! The Drug Bioinformatics group had a fantastic presence, with six members presenting their latest work across various COSIs. www.linkedin.com/feed/update/...

What an exciting week it's been at the #ISMBECCB2025 conference in Liverpool! | Roman Joeres

What an exciting week it's been at the #ISMBECCB2025 conference in Liverpool! The Drug Bioinformatics group, led by Olga Kalinina, had a fantastic presence, with six members presenting their latest wo...

linkedin.com

This week I presented DataSAIL at the #ISMBECCB2025 conference in #Liverpool It has been an amazing chance and experience to meet many people working on information leakage. And getting great ideas to extend it Nicely supervised by & colaborated with @dbblumenthal.bsky.social @ok55991.bsky.social

I am very excited to share the publication of our tool StructMAn 2.0 in the NAR webserver issue (10.1093/nar/gkaf381). If you want to annotate protein structures to protein sequences or if you are looking for structural evidence for PPIs, consider using: tools.helmholtz-hips.de/structman/

DataSAIL is out in @naturecomms.bsky.social Since the preprint, we have improved the work a lot, thanks to countless reviewers and feedback. You can find it here: nature.com/articles/s41... Thanks, @dbblumenthal.bsky.social and @ok55991.bsky.social, for helping and supervising me on this journey.