Amanda Melin

@amelinlab.bsky.social

Professor of Biological Anthropology at University of Calgary. Co-director Santa Rosa Primate Project. Primate sensory ecology, molecular genetics and omics, foraging, behaviour, ecology and evolution. She/Her. www.amandamelin.com

It’s out! We show that fecal cellular DNA methylation profiles provide accurate molecular clock for age estimation in wild capuchins; age-associated differences in DNAm are relevant to development, membrane excitability, and control of cell cycle. New opportunities for epigenetic study in the wild!

Baptiste Sadoughi@bsadoughi.bsky.social · 3w ago

🚨New Study Out🚨 In #MolecularEcology we used a new method to measure #DNAmethylation NON-INVASIVELY in wild capuchin monkeys 🐒🧬 We show that epithelial gut cells from feces encode species, age and sex, and can be used to build #aging clocks, run EWAS, and more onlinelibrary.wiley.com/doi/10.1111/...

A microbiome gut-brain pathway influenced by intestinal metabolites, innate immune responses, vagal nerve signaling and hippocampal memory encoding, impacts the rate of cognitive decline. Many potential points of intervention are described. #Science 🧪

Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature

Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...

nature.com

Todd with a Santa Rosa delicacy, squirrel tartare. Capuchins primarily eat fruit/seeds/insects but they are true omnivores. When the opportunity arises they will absolutely hunt bigger prey such as birds, lizards and mammals like this variegated squirrel

BildBildBild

It’s an RNA world. RNA is posited to be the first genetic material, arising 4 billion years ago. It can store information and act as an enzyme. Eventually, it duplicated its information into a more stable form, DNA.

A four panel comic, from left to right:

1960s
LIFE IS BASED ON DNA, WHICH USES RNA TO MAKE PROTEINS THAT DO STUFF.

1980s
ALSO, THE RNA DOES SOME STUFF ITSELF, WHICH IS WEIRD.

2000s
THERE ARE 50
MANY KINDS OF RNA. IT'S DOING SO MUCH STUFF!

2020s
LIFE IS A SEETHING MASS OF RNA THAT SOMETIMES USES DNA TO TAKE NOTES.

WHAT DO THE PROTEINS DO?
ERRANDS FOR RNA.

“Male Andrea cuttlefish (Doratosepion andreanum) – quite drab to human eyes – use their birefringent arms to literally twist light, creating a highly conspicuous signal precisely tuned to cuttlefish vision.” #scicomm www.sciencealert.com/cuttlefish-l... 🧪 🐙 🦑

Cuttlefish Literally Twist Light to Attract a Mate, Study Finds

Every critter on this planet that relies on a sexual means of reproduction has its own way of luring in a mate – but cuttlefish can do something really special.

sciencealert.com

Our new paper is online! We found that 1) today's shark & ray diversity was already reached ~100Ma; 2) that the K/Pg extinction was not catastrophic; 3) that the max diversity was reached ~50Ma; and 4) that today's diversity is depleted compared to the past. www.cell.com/current-biol...

Revealing the hidden patterns of shark and ray diversity over the past 145 million years

Gardiner et al. reconstruct the diversity of sharks and rays across the past 145 million years using deep learning and an extensive dataset. Their results unveil previously hidden patterns, including ...

cell.com