Very excited to share this collaborative work led by Kyriaki Neophytou. An extracellular Argonaute from a nematode parasite is transmitted to host cells and the non-vesicular form is functionally important (and now a vaccine candidate). An Argonaute vaccine... who would have thought.
A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival https://www.biorxiv.org/content/10.1101/2025.04.01.646544v1